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Publications

S Castellano and SR Eddy
A probabilistic interpretation of the Smith-Waterman algorithm
In preparation

A Merlos-Suarez, M Buchholz, A Heidenblut, J Luttges, S Castellano, T Gress, S Hahn and FX Real
A global analysis of the human pancreatic transcriptome defines a distinct gene expression profile in ductal cells
Submitted

JF Abril, S Castellano and R Guigó
Comparative gene prediction
M.D. Adams (Ed.). Humana Press. In press   [Invited chapter in A Guide to the Analysis of Eukaryotic Genomes book]

Fu, Q., A. Mittnik, P.L.F. Johnson, K. Bos, M. Lari, R. Bollongino, C. Sun, L. Giemsch, R. Schmitz, J. Burger, A.M. Ronchitelli, F. Martini, R.G. Cremonesi, J. Svoboda, P. Bauer, D. Caramelli, S. Castellano, D. Reich, S. Pääbo and J. Krause
A revised timescale for human evolution based on ancient mitochondrial genomes
Current Biology 23, 553-559 (2013) 

Romagné, F., D. Santesmasses, L. White, G.K. Sarangi, M. Mariotti, R. Hübler, A. Weihmann, G. Parra, V.N. Gladyshev, R. Guigo and S. Castellano
SelenoDB 2.0: high-quality annotation of selenoprotein genes in animals and their genetic diversity in humans 
Nucleic Acids Research
Accepted

White, L. and S. Castellano
Evolutionary basis for the use of selenocysteine
(Invited book chapter). In: Selenium: Its molecular biology and role in human health. (Eds.) D.L. Hatfield et al., Springer Science+Business Media, LLC, doi: 10.1007/978-1-4614-1025-6_7, 85-93 (2012) 

S Castellano
On the unique function of selenocysteine - insights from the evolution of selenoproteins
Biochimica et Biophysica Acta, 1790, 1463-1470 (2009) [Invited review in Selenoprotein expression and function special issue]

S Castellano*, AM Andrés*, E Bosch, M Bayes, R Guigó and AG Clark
Low exchangeability of selenocysteine, the 21st amino acid, in vertebrate proteins
Molecular Biology and Evolution, 26, 2031-2040 (2009)

S Castellano, VN Gladyshev, R Guigó and MJ Berry
SelenoDB 1.0: a database of selenoprotein genes, proteins and SECIS elements
Nucleic Acids Research, 36, D339-D343 (2008)   [Database]

S Castellano
Little biological and statistical support for hundreds of selenoproteins in mouse pseudo-messenger RNAs
PLoS Genetics, eLetters (2006)   [A critical assessment of computational experiments in PLoS Genetics, 2, e3 (2006)]

S Castellano, AV Lobanov, C Chapple, S Novoselov, M Albrecht, D Hua, A Lescure, T Lengauer, A Krol, VN Gladyshev and R Guigó
Diversity and functional plasticity of eukaryotic selenoproteins: identification and characterization of the SelJ family
Proceedings of the National Academy of Sciences USA, 102, 16188-16193 (2005)   [Commentary in PNAS]

K Taskov, C Chapple, GV Kryukov, S Castellano, AV Lobanov, KV Korotkov, R Guigó and VN Gladyshev
Nematode selenoproteome: the use of selenocysteine insertion system to decode one codon in an animal genome?
Nucleic Acids Research, 33, 2227-2238 (2005)

International Chicken Genome Sequencing Consortium
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
Nature, 432, 695-716 (2004)   [Commentary in Nature]

International Tetraodon Genome Sequencing Consortium
Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype
Nature, 431, 946-957 (2004)   [Commentary in Nature]   [F1000 evaluation]

S Castellano
Towards the characterization of the eukaryotic selenoproteome: a computational approach
PhD thesis, July 2004   [Cover PDF file]   [LaTeX template Tar file]

S Castellano, SV Novoselov, GV Kryukov, A Lescure, E Blanco, A Krol, VN Gladyshev and R Guigó
Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution
EMBO reports, 5, 71-77 (2004)   [Datasets]   [Commentary in EMBO]   [F1000 evaluation]

GV Kryukov, S Castellano, SV Novoselov, AV Lobanov, O Zehtab, R Guigó and VN Gladyshev
Characterization of mammalian selenoproteomes
Science, 300, 1439-1443 (2003)   [Datasets]

S Castellano, N Morozova, M Morey, MJ Berry, F Serras, M Corominas and R Guigó
in silico identification of novel selenoproteins in the Drosophila melanogaster genome
EMBO reports, 2, 697-702 (2001)   [Datasets]

*Equal contribution