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Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series. Yuan Y, Chen YP, Ni S, Xu AG, Tang L, Vingron M, Somel M, Khaitovich P (2011) BMC Bioinformatics 12(1):347 [link].
Rapid metabolic evolution in human prefrontal cortex. Fu X, Giavalisco P, Liu X, Catchpole G, Fu N, Ning ZB, Guo S, Yan Z, Somel M, Pääbo S, Zeng R, Willmitzer L, Khaitovich P (2011) Proc Natl Acad Sci U S A 108(15):6181-6 [link].
MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain.
Somel M*, Guo S*, Fu N*, Yan Z, Hu HY, Fu X, Yuan Y, Ning Z, Hu Y, Menzel C, Hu H, Lachmann M, Zeng R, Chen W, Khaitovich P (2010) Genome Research 20: 1207-1218 (*contributed equally) [link].
Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq.
Xu AG, He L, Li Z, Xu Y, Li M, Fu X, Yan Z, Yuan Y, Menzel C, Li N, Somel M, Hu H, Chen W, Pääbo S, Khaitovich P. (2010) PLoS Computational Biology 6(7):e1000843 [link].
Evolution of neuronal and endothelial transcriptomes in primates.
Giger T, Khaitovich P, Somel M, Lorenc A, Lizano E, Harris L, Ryan M, Lan M, Wayland M, Bahn S, Pääbo S. (2010) Genome Biology and Evolution 2:284-92 [link].
A humanized version of FoxP2 affects cortico-basal ganglia circuits in mice.
Enard W, Gehre S, Hammerschmidt K, Hölter SM, Blass T, Somel M, Bruckner MK, Schreiweis C, et al. (2009) Cell 137(5):961-71 [link].
Transcriptional Neoteny in the Human Brain.
Somel M, Franz H, Yan Z, Lorenc A, Guo S, Giger T, Kelso J, Nickel B, Dannemann M, Bahn S, Webster MJ, Weickert CS, Lachmann M, Pääbo S, Khaitovich P (2008) Proc Natl Acad Sci U S A 106(14):5743-8 [link].
Evolution of primate gene expression: drift and corrective sweeps?
Chaix R, Somel M, Kreil DP, Khaitovich P, Lunter GA. (2008) Genetics 180(3):1379-89 [link].
Metabolic changes in schizophrenia and human brain evolution. Khaitovich P, Lockstone HE, Wayland MT, Tsang TM, Jayatilaka SD, Guo AJ, Zhou J, Somel M, Harris LW, Holmes E, Pääbo S, Bahn S. (2008) Genome Biology 9(8):R124 [link].
Identification and analysis of genomic regions with large between-population differentiation in humans.
Myles S, Tang K, Somel M, Kelso J, Stoneking, M. (2008) Annals of Human Genetics 72(Pt 1):99-110 [pdf]
Human and chimpanzee gene expression differences replicated in mice fed different diets.
Somel M*, Creely H*, Franz H, Mueller U, Lachmann M, Khaitovich P, Pääbo S. (2008) PLoS ONE 30;3(1):e1504. (*contributed equally) [link]
Identifying genes underlying skin pigmentation differences among human populations.
Myles S, Somel M, Tang K, Kelso J, Stoneking, M. (2007) Human Genetics 120:613-621 [pdf]
Gene expression becomes heterogeneous with age.
Somel M, Khaitovich P, Bahn S, Pääbo S, Lachmann M. (2006) Current Biology 16(10):R359-60 [pdf]
Supplementary online material:
Somel et al. (2006) Gene expression becomes heterogeneous with age. -
Detailed procedures and discussion. [pdf]
Misc:
Genetic Footprints of Natural Selection and Drift in Human Evolution.
Somel M & Sezgin E (2010) Hacettepe Journal of Biology and Chemistry 38(3):193-220. [link]
Turks fighting back against anti-evolution forces.
Somel M, Somel RN, Kence A (2007) Nature 445(7124):147. [pdf]
Türkiye'de evrim kuramı eğitimine kısa bakış [An overview on the teaching of evolution in Turkey.].
Somel RN, Somel M, Tan MG, Kence A (2006) Cumhuriyet Bilim Teknik Sep 22, 2006. [doc]
Turkish science needs more than membership of the EU.
Somel M (2005) Nature 438:738. [pdf]
Characterisation of DNA from archaeological wheat (Triticum L.) seeds from Anatolia.
Somel M (2002) MSc thesis, METU, Ankara. [pdf]
Presentations:
Somel M et al. (2011) "MicroRNA-driven ontogenetic patterns show accelerated evolution in the human brain" SMBE, Kyoto, Japan.
Somel M (2010) "Testing mechanisms of aging using lifelong gene expression patterns in the primate brain" SMBE, Lyon, France.
Somel M, Hu HY, Yuan Y, Guo S, Yan Z, Xu Y, Lachmann M, Chen W, Pääbo S, Khaitovich P (2009) "Role of miRNAs in human brain evolution" ESEB, Torino, Italy.
Somel M, Franz H, Lorenc A, Giger T, Kelso J, Nickel B, Dannemann M, Bahn S, Webster MJ, Weickert CS, Lachmann M, Pääbo S, Khaitovich P (2008) "Brain development and ageing in primate brains." Ageing Symposium, Friburg, Switzerland.
Somel M, Lachmann M, Pääbo S, Khaitovich P (2007) “Gene expression patterns in primate brain development.”SMBE, Halifax, Canada.
Somel M, Creely HE, Khaitovich P, Lachmann M, Pääbo S (2006) “What can mouse models tell us about human-chimpanzee phenotypic differences?” SMBE, Tempe, AZ, USA
Somel M, Lachmann M, Khaitovich P, Lorenc A, Enard W, Pääbo S (2005) “Variation and parallelism within the ageing transcriptome.” ESEB, Krakow, Poland.
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