% pubman genre = article @article{item_3263719, title = {{The Genomic impact of European colonization of the Americas}}, author = {Ongaro, Linda and Scliar, Marilia O. and Flores, Rodrigo and Raveane, Alessandro and Marnetto, Davide and Sarno, Stefania and Gnecchi-Ruscone, Guido Alberto and Alarc{\'o}n-Riquelme, Marta E. and Patin, Etienne and Wangkumhang, Pongsakorn and Hellenthal, Garrett and Gonzalez-Santos, Miguel and King, Roy J. and Kouvatsi, Anastasia and Balanovsky, Oleg and Balanovska, Elena and Atramentova, Lubov and Turdikulova, Shahlo and Mastana, Sarabjit and Marjanovic, Damir and Mulahasanovic, Lejla and Leskovac, Andreja and Lima-Costa, Maria F. and Pereira, Alexandre C. and Barreto, Mauricio L. and Horta, Bernardo L. and Mabunda, N{\'e}dio and May, Celia A. and Moreno-Estrada, Andr{\'e}s and Achilli, Alessandro and Olivieri, Anna and Semino, Ornella and Tambets, Kristiina and Kivisild, Toomas and Luiselli, Donata and Torroni, Antonio and Capelli, Cristian and Tarazona-Santos, Eduardo and Metspalu, Mait and Pagani, Luca and Montinaro, Francesco}, language = {eng}, isbn = {0960-9822}, doi = {10.1016/j.cub.2019.09.076}, year = {2019}, date = {2019-12}, abstract = {{Summary{\textless}br{\textgreater}The human genetic diversity of the Americas has been affected by several events of gene flow that have continued since the colonial era and the Atlantic slave trade. Moreover, multiple waves of migration followed by local admixture occurred in the last two centuries, the impact of which has been largely unexplored. Here, we compiled a genome-wide dataset of $\sim$12,000 individuals from twelve American countries and $\sim$6,000 individuals from worldwide populations and applied haplotype-based methods to investigate how historical movements from outside the New World affected (1) the genetic structure, (2) the admixture profile, (3) the demographic history, and (4) sex-biased gene-flow dynamics of the Americas. We revealed a high degree of complexity underlying the genetic contribution of European and African populations in North and South America, from both geographic and temporal perspectives, identifying previously unreported sources related to Italy, the Middle East, and to specific regions of Africa.}}, journal = {{Current Biology}}, volume = {29}, number = {23}, pages = {3974--3986.e4}, }