% pubman genre = article
@article{item_3385591,
title = {{Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century}},
author = {Waldman, Shamam and Backenroth, Daniel and Harney, {\'E}adaoin and Flohr, Stefan and Neff, Nadia C. and Buckley, Gina M. and Fridman, Hila and Akbari, Ali and Rohland, Nadin and Mallick, Swapan and Nistal, Jorge Cano and Yu, Jin and Barzilai, Nir and Peter, Inge and Atzmon, Gil and Ostrer, Harry and Lencz, Todd and Maruvka, Yosef E. and L{\"a}mmerhirt, Maike and Rutgers, Leonard V. and Renson, Virginie and Prufer, Keith M. and Schiffels, Stephan and Ringbauer, Harald and Sczech, Karin and Carmi, Shai and Reich, David},
language = {eng},
issn = {0092-8674},
doi = {10.1016/j.cell.2022.11.002},
publisher = {Cell Press},
address = {Cambridge, Mass.},
year = {2022},
date = {2022-12},
abstract = {{We report genome-wide data for 33 Ashkenazi Jews (AJ), dated to the 14th century, following a salvage{\textless}br{\textgreater}excavation at the medieval Jewish cemetery of Erfurt, Germany. The Erfurt individuals are genetically{\textless}br{\textgreater}similar to modern AJ and have substantial Southern European ancestry, but they show more variability{\textless}br{\textgreater}in Eastern European-related ancestry than modern AJ. A third of the Erfurt individuals carried the same{\textless}br{\textgreater}nearly-AJ-specific mitochondrial haplogroup and eight carried pathogenic variants known to affect AJ{\textless}br{\textgreater}today. These observations, together with high levels of runs of homozygosity, suggest that the Erfurt{\textless}br{\textgreater}community had already experienced the major reduction in size that affected modern AJ. However, the{\textless}br{\textgreater}Erfurt bottleneck was more severe, implying substructure in medieval AJ. Together, our results suggest{\textless}br{\textgreater}that the AJ founder event and the acquisition of the main sources of ancestry pre-dated the 14th century{\textless}br{\textgreater}and highlight late medieval genetic heterogeneity no longer present in modern AJ.}},
journal = {{Cell}},
volume = {185},
number = {25},
pages = {4703--4716.e16},
}