Max-Planck-InstitutDepartment of Evolutionary Genetics
Max Planck Institute for Evolutionary Anthropology
Deutscher Platz 6
04103 Leipzig
phone: +49 341 3550 - 500
e-mail: mittag@[>>> Please remove the brackets! <<<]eva.mpg.de
Publications
2019
Giner-Delgado, C., Villatoro, S., Lerga-Jaso, J., Gayà-Vidal, M., Oliva, M., Castellano, D., Pantano, L., Bitarello, B. D., Izquierdo, D., Noguera, I., Olalde, I., Delprat, A., Blancher, A., Lalueza-Fox, C., Esko, T., O’Reilly, P. F., Andrés, A. M., Ferretti, L., Puig, M., & Cáceres, M. (2019). Evolutionary and functional impact of common polymorphic inversions in the human genome. Nature Communications,10(4222).  Open Access DOI BibTeX Endnote | |
| Bokelmann, L., Hajdinjak, M., Peyrégne, S., Brace, S., Essel, E., de Filippo, C., Glocke, I., Grote, S., Mafessoni, F., Nagel, S., Kelso, J., Prüfer, K., Vernot, B., Barnes, I., Pääbo, S., Meyer, M., & Stringer, C. (2019). A genetic analysis of the Gibraltar Neanderthals. Proceedings of the National Academy of Sciences,116(31), 15610-15615. DOI BibTeX Endnote | |
| Peyrégne, S., Slon, V., Mafessoni, F., de Filippo, C., Hajdinjak, M., Nagel, S., Nickel, B., Essel, E., Le Cabec, A., Wehrberger, K., Conard, N. J., Kind, C. J., Posth, C., Krause, J., Abrams, G., Bonjean, D., Di Modica, K., Toussaint, M., Kelso, J., Meyer, M., Pääbo, S., & Prüfer, K. (2019). Nuclear DNA from two early Neandertals reveals 80,000 years of genetic continuity in Europe. Science Advances,5(6): eaaw5873. Open Access DOI BibTeX Endnote |
2018
| Key, F. M., Abdul-Aziz, M. A., Mundry, R., Peter, B. M., Sekar, A., D'Amato, M., Dennis, M. Y., Schmidt, J. M., & Andrés, A. M. (2018). Human local adaptation of the TRPM8 cold receptor along a latitudinal cline. PLoS Genetics,14(5): e1007298. Open Access DOI BibTeX Endnote | |
| Bitarello, B. D., de Filippo, C.,Teixeira, J. C., Schmidt, J. M., Kleinert, P., Meyer, D., & Andrés, A. M. (2018). Signatures of long-term balancing selection in human genomes. Genome Biology and Evolution,10(3), 939-955. Open Access DOI BibTeX Endnote |
2017
| Prüfer, K., Filippo, C. d., Grote, S., Mafessoni, F., Korlevic, P., Hajdinjak, M., Vernot, B., Skov, L., Hsieh, P., Peyrégne, S.,Reher, D., Hopfe, C., Nagel, S., Maricic, T., Fu, Q., Theunert, C., Rogers, R., Skoglund, P., Chintalapati, M., Dannemann, M., Nelson, B. J., Key, F. M., Rudan, P., Kucan, Ž., Gušic, I., Golovanova, L. V., Doronichev, V. B., Patterson, N., Reich, D., Eichler, E. E., Slatkin, M., Schierup, M. H., Andrés, A. M., Kelso, J., Meyer, M., & Pääbo, S. (2017). A high-coverage Neandertal genome from Vindija Cave in Croatia. Science,358(6363), 655-658. DOI BibTeX Endnote | |
| Reher, D., Klink, B., Deutsch, A., & Voss-Böhme, A. (2017). Cell adhesion heterogeneity reinforces tumour cell dissemination: Novel insights from a mathematical model. Biology Direct,12: 18. Open Access DOI BibTeX Endnote |
2016
| de Manuel, M., Kuhlwilm, M., Frandsen, P., Sousa, V. C., Desai, T., Prado-Martinez, J., Hernandez-Rodriguez, J., Dupanloup, I., Lao, O., Hallast, P., Schmidt, J. M., Heredia-Genestar, J. M., Benazzo, A., Barbujani, G., Peter, B. M., Kuderna, L. F. K., Casals, F., Angedakin, S., Arandjelovic, M., Boesch, C., Kühl, H. S., Vigilant, L., Langergraber, K., Novembre, J., Gut, M., Gut, I., Navarro, A., Carlsen, F., Andrés, A. M., Siegismund, H. R., Scally, A., Excoffier, L., Tyler-Smith, C., Castellano, S., Xue, Y., Hvilsom, C., & Marques-Bonet, T. (2016). Chimpanzee genomic diversity reveals ancient admixture with bonobos. Science,354(6311), 477-481. DOI BibTeX Endnote | |
| Lobon, I., Tucci, S., de Manuel, M., Ghirotto, S., Benazzo, A., Prado-Martinez, J., Lorente-Galdos, B., Nam, K., Dabad, M., Hernandez-Rodriguez, J., Comas, D., Navarro, A., Schierup, M. H., Andrés, A. M., Barbujani, G., Hvilsom, C., & Marques-Bonet, T. (2016). Demographic history of the genus Pan inferred from whole mitochondrial genome reconstructions. Genome Biology and Evolution,8(10), 2020-2030. Open Access DOI BibTeX Endnote | |
| de Filippo, C.,Key, F. M., Ghirotto, S., Benazzo, A., Meneu, J. R., Weihmann, A., NISC Comparative Sequence Program, Parra, G., Green, E. D., & Andrés, A. M. (2016). Recent selection changes in human genes under long-term balancing selection. Molecular Biology and Evolution,33(6), 1435-1447. DOI BibTeX Endnote | |
| Meyer, M., Arsuaga, J.-L., de Filippo, C., Nagel, S., Aximu-Petri, A., Nickel, B., Martínez, I., Gracia, A., Bermúdez de Castro, J. M., Carbonell, E., Viola, B., Kelso, J., Prüfer, K., & Pääbo, S. (2016). Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins. Nature,531(7595), 504-507. DOI BibTeX Endnote | |
| Key, F. M., Fu, Q., Romagné, F., Lachmann, M., & Andrés, A. M. (2016). Human adaptation and population differentiation in the light of ancient genomes. Nature Communications,7: 10775. Open Access DOI BibTeX Endnote | |
| Andrés, A. M., Dannemann, M., Teixeira, J. C., & Kelso, J. (2016). Balancing selection and adaptive introgression as sources of advantageous genetic diversity in populations. American Journal of Physical Anthropology,159(S62), 80-81. DOI BibTeX Endnote | |
| Kuhlwilm, M., Gronau, I., Hubisz, M. J., de Filippo, C., Prado-Martinez, J., Kircher, M., Fu, Q., Burbano, H. A., Lalueza-Fox, C., de la Rasilla, M., Rosas, A., Rudan, P., Brajkovic, D., Kucan, Ž., Gušic, I., Marques-Bonet, T., Andrés, A. M., Viola, B., Pääbo, S., Meyer, M., Siepel, A., & Castellano, S. (2016). Ancient gene flow from early modern humans into Eastern Neanderthals. Nature,530(7591), 429-433. DOI BibTeX Endnote | |
| Dannemann, M., Andrés, A. M., & Kelso, J. (2016). Introgression of Neandertal- and Denisovan-like haplotypes contributes to adaptive variation in human toll-like receptors. The American Journal of Human Genetics,98(1), 22-33. Open Access DOI BibTeX Endnote | |
| Cagan, A., Theunert, C., Laayouni, H., Santpere, G., Pybus, M., Casals, F., Prüfer, K., Navarro, A., Marques-Bonet, T., Bertranpetit, J., & Andrés, A. M. (2016). Natural selection in the great apes. Molecular Biology and Evolution,33(12), 3268-3283. Open Access DOI BibTeX Endnote | |
| Key, F. M. (2016). Human adaptation in the light of ancient and modern genomes. PhD Thesis, Univ., Leipzig. BibTeX Endnote |
2015
| Teixeira, J. C.,de Filippo, C., Weihmann, A., Meneu, J. R., Racimo, F., Dannemann, M., Nickel, B., Fischer, A., Halbwax, M., Andre, C., Atencia, R., Meyer, M., Parra, G., Pääbo, S., & Andrés, A. M. (2015). Long-term balancing selection in LAD1 maintains a missense trans-species polymorphism in humans, chimpanzees and bonobos. Molecular Biology and Evolution,32(5), 1186-1196. DOI BibTeX Endnote | |
| White, L., Romagné, F., Müller, E., Erlebach, E., Weihmann, A., Parra, G.,Andrés, A. M., & Castellano, S. (2015). Genetic adaptation to levels of dietary selenium in recent human history. Molecular Biology and Evolution,32(6), 1507-1518. DOI PubMed BibTeX Endnote |
2014
| Andrés, A. M., & Nowick, K. ( BibTeX Endnote | |
| Andrés, A. M., & Nowick, K. (2014). Editorial overview: Genetics of human evolution: The genetics of human origins. Current Opinion in Genetics & Development,29, v-vii. DOI BibTeX Endnote | |
| Key, F. M.,Teixeira, J. C.,de Filippo, C., & Andrés, A. M. (2014). Advantageous diversity maintained by balancing selection in humans. Current Opinion in Genetics & Development,29, 45-51. DOI PubMed BibTeX Endnote | |
| Key, F. M., Peter, B., Dennis, M. Y., Huerta-Sanchez, E., Tang, W., Prokunina-Olsson, L., Nielsen, R., & Andrés, A. M. (2014). Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of Interferon Lambda 4 (IFNL 4). PLoS Genetics,10(10): e1004681. Open Access DOI PubMed BibTeX Endnote | |
| Prüfer, K., Racimo, F., Patterson, N., Jay, F., Sankararaman, S., Sawyer, S., Heinze, A., Renaud, G., Sudmant, P. H., de Filippo, C., Li, H., Mallick, S., Dannemann, M., Fu, Q., Kircher, M., Kuhlwilm, M., Lachmann, M., Meyer, M., Ongyerth, M., Siebauer, M. F., Theunert, C., Tandon, A., Moorjani, P., Pickrell, J., Mullikin, J. C., Vohr, S. H., Green, R. E., Hellmann, I., Johnson, P. L. F., Blanche, H., Cann, H., Kitzman, J. O., Shendure, J., Eichler, E. E., Lein, E. S., Bakken, T. E., Golovanova, L. V., Doronichev, V. B., Shunkov, M. V., Derevianko, A. P., Viola, B., Slatkin, M., Reich, D., Kelso, J., & Pääbo, S. (2014). The complete genome sequence of a Neanderthal from the Altai Mountains. Nature,505(7481), 43-49. DOI BibTeX Endnote | |
| Castellano, S., Parra, G., Sánchez-Quinto, F. A., Racimo, F., Kuhlwilm, M., Kircher, M., Sawyer, S., Fu, Q., Heinze, A., Nickel, B., Dabney, J., Siebauer, M. F., White, L., Burbano, H. A., Renaud, G., Stenzel, U., Lalueza-Fox, C., de la Rasilla, M., Rosas, A., Rudan, P., Brajkovic, D., Kucan, Ž., Gušic, I., Shunkov, M. V., Derevianko, A. P., Viola, B., Meyer, M., Kelso, J., Andrés, A. M., & Pääbo, S. (2014). Patterns of coding variation in the complete exomes of three Neandertals. Proceedings of the National Academy of Sciences of the United States of America,111(18), 6666-6671. DOI PubMed BibTeX Endnote | |
| Hajdinjak, M., Korlević, P., Gansauge, M.-T., Dabney, J., Slon, V., Glocke, I., Sawyer, S., Nickel, B., Nagel, S., Gerber, T., Hopfe, C., Stenzel, U., Renaud, G., Andrés, A. M., Castellano, S., Kelso, J., Prüfer, K., Meyer, M., & Pääbo, S. (2014).Neandertal genetic diversity. Poster presented at XVII World UISPP Congress, Burgos, Spain. BibTeX Endnote |
2013
| Prado-Martinez, J., Sudmant, P. H., Kidd, J. M., Li, H., Kelley, J. L., Lorente-Galdos, B., Veeramah, K. R., Woerner, A. E., O’Connor, T. D., Santpere, G., Cagan, A., Theunert, C., Casals, F., Laayouni, H., Munch, K., Hobolth, A., Halager, A. E., Malig, M., Hernandez-Rodriguez, J., Hernando-Herraez, I., Prüfer, K., Pybus, M., Johnstone, L., Lachmann, M., Alkan, C., Twigg, D., Petit, N., Baker, C., Hormozdiari, F., Fernandez-Callejo, M., Dabad, M., Wilson, M. L., Stevison, L., Camprubí, C., Carvalho, T., Ruiz-Herrera, A., Vives, L., Mele, M., Abello, T., Kondova, I., Bontrop, R. E., Pusey, A., Lankester, F., Kiyang, J. A., Bergl, R. A., Lonsdorf, E., Myers, S., Ventura, M., Gagneux, P., Comas, D., Siegismund, H., Blanc, J., Agueda-Calpena, L., Gut, M., Fulton, L., Tishkoff, S. A., Mullikin, J. C., Wilson, R. K., Gut, I. G., Gonder, M. K., Ryder, O. A., Hahn, B. H., Navarro, A., Akey, J. M., Bertranpetit, J., Reich, D., Mailund, T., Schierup, M. H., Hvilsom, C., Andrés, A. M., Wall, J. D., Bustamante, C. D., Hammer, M. F., Eichler, E. E., & Marques-Bonet, T. (2013). Great ape genetic diversity and population history. Nature,499, 471-475. Open Access DOI PubMed BibTeX Endnote | |
| Ferreira, Z., Seixas, S., Andrés, A. M., Kretzschmar, W. W., Mullikin, J. C., Cherukuri, P. F., Cruz, P., Swanson, W. J., Clark, A. G., Green, E. D., & Hurle, B. (2013). Reproduction and immunity-driven natural selection in the human WFDC locus. Molecular Biology and Evolution,30(4), 938-950. DOI PubMed BibTeX Endnote | |
| Ferreira, Z., Hurle, B., Andrés, A. M., Kretzschmar, W. W., Mullikin, J. C., Cherukuri, P. F., Cruz, P., Gonder, M. K., Stone, A. C., Tishkoff, S., Swanson, W. J., NISC Comparative Sequencing Program, Green, E. D., Clark, A. G., & Seixas, S. (2013). Sequence diversity of Pan troglodytes subspecies and the impact of WFDC6 selective constraints in reproductive immunity. Genome Biology and Evolution,5(12), 2512-2523. Open Access DOI PubMed BibTeX Endnote |
2012
| Meyer, M., Kircher, M., Gansauge, M.-T., Li, H., Racimo, F., Mallick, S., Schraiber, J. G., Jay, F., Prüfer, K., Filippo, C. d., Sudmant, P. H., Alkan, C., Fu, Q., Do, R., Rohland, N., Tandon, A., Siebauer, M., Green, R. E., Bryc, K., Briggs, A. W., Stenzel, U., Dabney, J., Shendure, J., Kitzman, J., Hammer, M. F., Shunkov, M. V., Derevianko, A. P., Patterson, N., Andrés, A. M., Eichler, E. E., Slatkin, M., Reich, D., Kelso, J., & Pääbo, S. (2012). A high-coverage genome sequence from an archaic Denisovan individual. Science,338(6104), 222-226. DOI PubMed BibTeX Endnote | |
| Prüfer, K., Munch, K., Hellmann, I., Akagi, K., Miller, J. R., Walenz, B., Koren, S., Sutton, G., Kodira, C., Winer, R., Knight, J. R., Mullikin, J. C., Meader, S. J., Ponting, C. P., Lunter, G., Higashino, S., Hobolth, A., Dutheil, J., Karakoç, E., Alkan, C., Sajjadian, S., Catacchio, C. R., Ventura, M., Marques-Bonet, T., Eichler, E. E., André, C., Atencia, R., Mugisha, L., Junhold, J., Patterson, N., Siebauer, M., Good, J. M., Fischer, A., Ptak, S. E., Lachmann, M., Symer, D. E., Mailund, T., Schierup, M. H., Andrés, A. M., Kelso, J., & Pääbo, S. (2012). The bonobo genome compared with the chimpanzee and human genomes. Nature,486(7404), 527-531. Open Access DOI PubMed BibTeX Endnote |
2011
| Andrés, A. M. (2011). Balancing selection in the human genome. In Encyclopedia of Life Sciences. Chichester [u.a.]: Wiley. DOI BibTeX Endnote |
2010
| Andrés, A. M., Dennis, M. Y., Kretzschmar, W. W., Cannons, J. L., Lee-Lin, S.-Q., Hurle, B., NISC Comparative Sequencing Program, Schwartzberg, P. L., Williamson, S. H., Bustamante, C. D., Nielsen, R., Clark, A. G., & Green, E. D. (2010). Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation. PLoS Genetics,6(10): e1001157. Open Access DOI PubMed BibTeX Endnote |
Selected publications before 2010
Andrés AM, Hubisz MJ, Indap A, Torgerson DG, Degenhardt JD, Boyko AR, Gutenkunst RN, White TJ, Green ED, Bustamante CD, Clark AG, Nielsen R. (2009). Targets of balancing selection in the human genome. Molecular Biology and Evolution, 26:2755-64.
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Castellano S*, Andrés AM*, Bosch E, Bayes M, Guigó R, Clark AG. (2009). Low exchangeability of selenocysteine, the 21st amino acid, in vertebrate proteins. Molecular Biology and Evolution, 26:2031-40.
PubMed Full Text PDF Supplementary Material
* Denotes equal contribution.
Nielsen R, Hubisz MJ, Hellmann I, Torgerson D, Andrés AM, Albrechtsen A, Gutenkunst R, Adams MD, Cargill M, Boyko A, Indap A, Bustamante CD, and Clark AG. (2009). Darwinian and demographic forces affecting human protein coding genes. Genome Research, 19:838-49.
PubMed Full Text PDF Supplementary Material
Andrés AM, Clark AG, Shimmin L, Boerwinkle E, Sing CF and Hixson JE. (2007). Understanding the accuracy of statistical haplotype inference with sequence data of known phase. Genetic Epidemiology, 31:659-71.
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Andrés AM, de Hemptinne C and Bertranpetit J. (2007). Heterogenetous rate of protein evolution in serotonin genes. Molecular Biology and Evolution, 24:2707-15.
PubMed Full text PDF Supplementary Material
Soldevila M, Andrés AM, Helgason A, Ramírez-Soriano A, Marquès-Bonet T, Sigurdadóttir S, Calafell F, Navarro A, Stefánsson K and Bertranpetit J. (2006). The prion protein gene in humans revisited: lessons from a worldwide resequencing study. Genome Research, 16:231-9.
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Andrés AM, Soldevila M, Navarro A, Kidd KK, Oliva B and Bertranpetit J. (2004). Positive selection in MAOA gene is human exclusive: determination of the putative amino acid change selected in the human lineage. Human Genetics 115:377-86.
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Andrés AM, Soldevila M, Lao O, Volpini V, Saitou N, Jacobs HT, Hayasaka I, Calafell F and Bertranpetit J. (2004). Comparative genetics of functional trinucleotide tandem repeats in humans and apes. Journal of Molecular Evolution 59:329-39.
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Clarimón J, Andrés AM, Bertranpetit J and Comas D. (2004). Comparative analysis of Alu insertion sequences in the APP 5’flanking region in humans and other primates. Journal of Molecular Evolution 58:722-731 (2004).
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Soldevila M, Andrés AM, Blancher A, Calafell F, Ordoñez M, Pumarola M, Oliva B, Aramburu J and Bertranpetit J. (2004). Variation of the prion gene in chimpanzees and its implication for prion diseases. Neuroscience Letters 355:157-60.
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Andrés AM, Soldevila M, Saitou N, Volpini V, Calafell F and Bertranpetit J. (2003). Understanding the dynamics of Spinocerebellar Ataxia 8 (SCA8) locus through a comparative genetic approach in humans and apes. Neuroscience Letters 336:143-146.
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Andrés AM, Lao O, Soldevila M, Calafell F and Bertranpetit J. (2003). Dynamics of CAG repeat loci revealed by the analysis of their variability. Human Mutation 21:61-70.
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Martínez-Arias R, Calafell R, Mateu E, Comas D, Andrés A and Bertranpetit J. (2002). Sequence variability of a human pseudogene. Genome Research 11:1071-1085.
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