% pubman genre = article @article{item_2424212, title = {{Functional implications of Neandertal introgression in modern humans}}, author = {Dannemann, Michael and Pr{\"u}fer, Kay and Kelso, Janet}, language = {eng}, issn = {1465-6906; 1474-760X}, doi = {10.1186/s13059-017-1181-7}, publisher = {BioMed Central Ltd.}, address = {London}, year = {2017}, abstract = {{Admixture between early modern humans and Neandertals approximately 50,000{\textendash}60,000 years ago has resulted in 1.5{\textendash}4{\textpercent} Neandertal ancestry in the genomes of present-day non-Africans. Evidence is accumulating that some of these archaic alleles are advantageous for modern humans, while others are deleterious; however, the major mechanism by which these archaic alleles act has not been fully explored.}}, journal = {{Genome Biology}}, volume = {18}, eid = {61}, }