% pubman genre = article @article{item_2638935, title = {{Ontogeny and variability of trabecular bone in the chimpanzee humerus, femur and tibia}}, author = {Tsegai, Zewdi J. and Skinner, Matthew M. and Pahr, Dieter H. and Hublin, Jean-Jacques and Kivell, Tracy L.}, language = {eng}, issn = {0002-9483; 1096-8644}, doi = {10.1002/ajpa.23696}, publisher = {Wiley Periodicals, Inc.}, address = {Hoboken, New Jersey}, year = {2018}, date = {2018-12}, abstract = {{Objectives: Trabecular bone structure is known to be influenced by joint loading during life.{\textless}br{\textgreater}However, many additional variables have the potential to contribute to trabecular bone struc-{\textless}br{\textgreater}ture of an adult individual, including age, sex, body size, genetics, and overall activity level. There{\textless}br{\textgreater}is little research into intraspecific variability in trabecular bone and ontogeny of trabecular bone{\textless}br{\textgreater}structure, especially in nonhuman primates.{\textless}br{\textgreater}Materials and methods: This study investigates trabecular structure in adult and immature chim-{\textless}br{\textgreater}panzees from a single population using high-resolution microcomputed tomographic scans of{\textless}br{\textgreater}the proximal humerus, proximal femur, and distal tibia. Trabecular bone volume fraction{\textless}br{\textgreater}(BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular spacing (Tb.Sp), and{\textless}br{\textgreater}degree of anisotropy (DA) were quantified in specific regions of adult and immature chimpan-{\textless}br{\textgreater}zees, and color maps were generated to visualize the distribution of BV/TV throughout the joint{\textless}br{\textgreater}in the metaphysis of immature specimens.{\textless}br{\textgreater}Results: The results demonstrate that variability in adult trabecular structure cannot be{\textless}br{\textgreater}explained by sex or body size. During ontogeny, there is a general increase in trabecular BV/TV{\textless}br{\textgreater}and Tb.Th with age, and ratios of trabecular parameters between the fore- and hindlimb may be{\textless}br{\textgreater}consistent with locomotor transitions during ontogeny.{\textless}br{\textgreater}Discussion: Variation in trabecular morphology among adult individuals is not related to sex or{\textless}br{\textgreater}body size, and the factors contributing to intraspecific variability, such as overall activity levels{\textless}br{\textgreater}and genetic differences, require further investigation. Trabecular ontogeny in chimpanzees dif-{\textless}br{\textgreater}fers from humans in some respects, most notably the absence of a high BV/TV at birth.}}, journal = {{American Journal of Physical Anthropology}}, volume = {167}, number = {4}, pages = {713--736}, }