% pubman genre = preprint @misc{item_3256929, title = {{Characterizing the genetic history of admixture across inner Eurasia}}, author = {Jeong, Choongwon and Balanovsky, Oleg and Lukianova, Elena and Kahbatkyzy, Nurzhibek and Flegontov, Pavel and Zaporozhchenko, Valery and Immel, Alexander and Wang, Chuan-Chao and Ixan, Olzhas and Khussainova, Elmira and Bekmanov, Bakhytzhan and Zaibert, Victor and Lavryashina, Maria and Pocheshkhova, Elvira and Yusupov, Yuldash and Agdzhoyan, Anastasiya and Sergey, Koshel and Bukin, Andrei and Nymadawa, Pagbajabyn and Churnosov, Michail and Skhalyakho, Roza and Daragan, Denis and Bogunov, Yuri and Bogunova, Anna and Shtrunov, Alexandr and Dubova, Nadezda and Zhabagin, Maxat and Yepiskoposyan, Levon and Churakov, Vladimir and Pislegin, Nikolay and Damba, Larissa and Saroyants, Ludmila and Dibirova, Khadizhat and Artamentova, Lubov and Utevska, Olga and Idrisov, Eldar and Kamenshchikova, Evgeniya and Evseeva, Irina and Metspalu, Mait and Robbeets, Martine and Djansugurova, Leyla and Balanovska, Elena and Schiffels, Stephan and Haak, Wolfgang and Reich, David and Krause, Johannes}, language = {eng}, url = {https://www.biorxiv.org/}, doi = {10.1101/327122}, year = {2018}, abstract = {{The indigenous populations of inner Eurasia, a huge geographic region covering the central Eurasian steppe and the northern Eurasian taiga and tundra, harbor tremendous diversity in their genes, cultures and languages. In this study, we report novel genome-wide data for 763 individuals from Armenia, Georgia, Kazakhstan, Moldova, Mongolia, Russia, Tajikistan, Ukraine, and Uzbekistan. We furthermore report genome-wide data of two Eneolithic individuals ({\textasciitilde}5,400 years before present) associated with the Botai culture in northern Kazakhstan. We find that inner Eurasian populations are structured into three distinct admixture clines stretching between various western and eastern Eurasian ancestries. This genetic separation is well mirrored by geography. The ancient Botai genomes suggest yet another layer of admixture in inner Eurasia that involves Mesolithic hunter-gatherers in Europe, the Upper Paleolithic southern Siberians and East Asians. Admixture modeling of ancient and modern populations suggests an overwriting of this ancient structure in the Altai-Sayan region by migrations of western steppe herders, but partial retaining of this ancient North Eurasian-related cline further to the North. Finally, the genetic structure of Caucasus populations highlights a role of the Caucasus Mountains as a barrier to gene flow and suggests a post-Neolithic gene flow into North Caucasus populations from the steppe.}}, journal = {{bioRxiv}}, eid = {327122}, }