% pubman genre = article @article{item_3257180, title = {{Genetic diversity of HLA system in two populations from Sinaloa, Mexico: Culiac{\'a}n and rural Sinaloa}}, author = {Clayton, Stephen and Barquera, Rodrigo and Uribe-Duarte, Mar{\'\i}a Guadalupe and V{\'a}zquez, Isis Gon{\'e} and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Arrieta-Bola{\~n}os, Esteban and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and de Ru{\'\i}z-Corral, Mar{\'\i}a Jes{\'u}s and Escobedo-Ru{\'\i}z, Araceli and Arellano-Prado, Francia Paulina and Garc{\'\i}a-Arias, V{\'\i}ctor Eduardo and Rodr{\'\i}guez-L{\'o}pez, Marla Estefan{\'\i}a and Bravo-Acevedo, Alicia and de S{\'a}nchez-Fern{\'a}ndez, Mar{\'\i}a Guadalupe Jes{\'u}s and Aguilar-Campos, Jes{\'u}s Abraham and Serrano-Osuna, Ricardo and G{\'o}mez-Navarro, Benjam{\'\i}n and Sandoval-Sandoval, Mario J. and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.06.006}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 286 Mexicans from the state of Sinaloa living in Culiac{\'a}n (N {\textequals} 103) and rural communities (N {\textequals} 183) to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes for the state of Sinaloa include ten Native American most probable ancestry and five European most probable ancestry haplotypes. The admixture estimates revealed that the main genetic components in the state of Sinaloa are European (62.39 $\pm$ 3.47) and Native American (37.61 $\pm$ 2.85), while the African genetic component was estimated as virtually absent (0.00 $\pm$ 1.86).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {482--484}, }