% pubman genre = article @article{item_3257184, title = {{Genetic diversity of HLA system in a population from Guerrero, Mexico}}, author = {Ju{\'a}rez-Nicol{\'a}s, Francisco and Barquera, Rodrigo and Mart{\'\i}nez-{\'A}lvarez, Julio C{\'e}sar and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and Ortega-Y{\'a}{\~n}ez, Andrea and Arrieta-Bola{\~n}os, Esteban and Clayton, Stephen and Bravo-Acevedo, Alicia and Arrazola-Garc{\'\i}a, Mar{\'\i}a Araceli and Immel, Alexander and Ju{\'a}rez-Barreto, Vicencio and Ben{\'\i}tez-Arvizu, Gamaliel and Vega-Mart{\'\i}nez, Mar{\'\i}a del Rosario and Garc{\'\i}a-{\'A}lvarez, Raquel and Mart{\'\i}nez-Bezies, Virginia and Escutia-Gonz{\'a}lez, Ariadna Berenice and D{\'\i}az-L{\'o}pez, Rosario and Guizar-L{\'o}pez, Gregorio Ulises and Salgado-Galicia, Norma and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.05.015}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 144 Mexicans from the state of Guerrero to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in the state of Guerrero include eight Native American and two European haplotypes. Admixture estimates revealed that the main genetic components in the state of Guerrero are Native American (61.36 $\pm$ 2.69 by ML; 54.17 of Native American haplotypes) and European (35.01 $\pm$ 4.59 by ML; 32.29 of European haplotypes), and a relatively low African genetic component (3.63 $\pm$ 2.38 by ML; 5.90 of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {550--552}, }