% pubman genre = article @article{item_3257201, title = {{Genetic diversity of HLA system in two populations from Morelos, Mexico: Cuernavaca and rural Morelos}}, author = {Ortega-Y{\'a}{\~n}ez, Andrea and Barquera, Rodrigo and Curiel-Giles, Laura and Mart{\'\i}nez-{\'A}lvarez, Julio C{\'e}sar and Mac{\'\i}as-Medrano, Rosa Mar{\'\i}a and Arrieta-Bola{\~n}os, Esteban and Clayton, Stephen and Bravo-Acevedo, Alicia and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and Immel, Alexander and Vega-Mart{\'\i}nez, Mar{\'\i}a del Rosario and Ben{\'\i}tez-Arvizu, Gamaliel and Arrazola-Garc{\'\i}a, Mar{\'\i}a Araceli and Arriaga-Perea, Agust{\'\i}n Jeric{\'o} and Ju{\'a}rez-Cort{\'e}s, Eva Dolores and Ju{\'a}rez-Barreto, Vicencio and Salgado-Galicia, Norma and Novelo-Garza, B{\'a}rbara and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.07.289}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 112 Mexicans from the state of Morelos living in the city of Cuernavaca (N {\textequals} 82) and rural communities (N {\textequals} 30), to obtain information regarding allelic and haplotypic frequencies. The most frequent haplotypes in Morelos include seven Native American, one European, one African and one Asian haplotype. Admixture estimates revealed that the main genetic components in Morelos are Native American (60.43 $\pm$ 2.22 by ML; 53.57 of Native American haplotypes) and European (39.58 $\pm$ 3.70 by ML; 27.68 of European haplotypes), and a virtually absent African genetic component (0.00 $\pm$ 4.93 by ML; but 11.16 of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {557--559}, }