% pubman genre = article
@article{item_3257212,
title = {{Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes}},
author = {Spyrou, Maria A. and Keller, Marcel and Tukhbatova, Rezeda I. and Scheib, Christiana L. and Nelson, Elizabeth A. and Andrades Valtue{\~n}a, Aida and Neumann, Gunnar and Walker, Don and Alterauge, Amelie and Carty, Niamh and Cessford, Craig and Fetz, Hermann and Gourvennec, Micha{\"e}l and Hartle, Robert and Henderson, Michael and von Heyking, Kristin and Inskip, Sarah A. and Kacki, Sacha and Key, Felix M. and Knox, Elizabeth L. and Later, Christian and Maheshwari-Aplin, Prishita and Peters, Joris and Robb, John E. and Schreiber, J{\"u}rgen and Kivisild, Toomas and Castex, Dominique and L{\"o}sch, Sandra and Harbeck, Michaela and Herbig, Alexander and Bos, Kirsten I. and Krause, Johannes},
language = {eng},
issn = {2041-1723},
doi = {10.1038/s41467-019-12154-0},
publisher = {Nature Publishing Group},
address = {London},
year = {2019},
abstract = {{The second plague pandemic, caused by Yersinia pestis, devastated Europe and the nearby regions between the 14th and 18th centuries AD. Here we analyse human remains from ten European archaeological sites spanning this period and reconstruct 34 ancient Y. pestis genomes. Our data support an initial entry of the bacterium through eastern Europe, the absence of genetic diversity during the Black Death, and low within-outbreak diversity thereafter. Analysis of post-Black Death genomes shows the diversification of a Y. pestis lineage into multiple genetically distinct clades that may have given rise to more than one disease reservoir in, or close to, Europe. In addition, we show the loss of a genomic region that includes virulence-related genes in strains associated with late stages of the pandemic. The deletion was also identified in genomes connected with the first plague pandemic (541-750 AD), suggesting a comparable evolutionary trajectory of Y. pestis during both events.}},
journal = {{Nature Communications}},
volume = {10},
number = {1},
eid = {4470},
}