% pubman genre = article @article{item_3257227, title = {{Genetic diversity of HLA system in two populations from Quer{\'e}taro, Mexico: Quer{\'e}taro city and rural Quer{\'e}taro}}, author = {Mart{\'\i}nez-{\'A}lvarez, Julio C{\'e}sar and Barquera Lozano, Rodrigo Jos{\'e} and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and Bravo-Acevedo, Alicia and Clayton, Stephen and Arrieta-Bola{\~n}os, Esteban and Immel, Alexander and Ben{\'\i}tez-Arvizu, Gamaliel and Arrazola-Garc{\'\i}a, Mar{\'\i}a Araceli and Ju{\'a}rez-Barreto, Vicencio and Vega-Mart{\'\i}nez, Mar{\'\i}a del Rosario and Ju{\'a}rez-Nicol{\'a}s, Francisco and Escutia-Gonz{\'a}lez, Ariadna Berenice and Mart{\'\i}nez-Bezies, Virginia and Garc{\'\i}a-{\'A}lvarez, Raquel and Salgado-Galicia, Norma and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.07.296}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 88 Mexicans from the state of Quer{\'e}taro living in the city of Quer{\'e}taro (N {\textequals} 45) and rural communities (N {\textequals} 43), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Quer{\'e}taro include seven Native American, two European and one Asian haplotype. Admixture estimates revealed that the main genetic components in the state of Quer{\'e}taro are Native American (51.82 $\pm$ 4.42 by ML; 42.61 of Native American haplotypes) and European (48.18 $\pm$ 3.55 by ML; 46.02 of European haplotypes), with a virtually absent African genetic component (0.00 $\pm$ 4.25 by ML; 4.55 of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {522--524}, }