% pubman genre = article @article{item_3257228, title = {{Genetic diversity of HLA system in two populations from San Luis Potos{\'\i}, Mexico: San Luis Potos{\'\i} City and rural San Luis Potos{\'\i}}}, author = {Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and Rodr{\'\i}guez-Mungu{\'\i}a, Tirzo Jes{\'u}s and Barquera, Rodrigo and Adalid-S{\'a}inz, Carmen and Arrieta-Bola{\~n}os, Esteban and Clayton, Stephen and Pacheco-Ubaldo, Hanna and Gonz{\'a}lez-Medina, Liliana and Lona-S{\'a}nchez, Abraham and Bravo-Acevedo, Alicia and Aquino-Rubio, Guadalupe and Gonz{\'a}lez-Mart{\'\i}nez, Marisela del Roc{\'\i}o and Delgado-Aguirre, H{\'e}ctor and Escare{\~n}o-Montiel, N{\'e}stor and Jaramillo-Rodr{\'\i}guez, Yolanda and Salgado-Adame, Antonio and la Cruz, Federico Ju{\'a}rez-de and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.07.291}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 117 Mexicans from the state of San Luis Potos{\'\i} living in the city of San Luis Potos{\'\i} (N {\textequals} 30) and rural communities (N {\textequals} 87), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state include 13 Native American, six European, two African and two Asian haplotypes. Admixture estimates revealed that the main genetic components are Native American (52.72 $\pm$ 0.66 by ML; 48.29 of Native American haplotypes) and European (34.62 $\pm$ 4.28 by ML; 32.48 of European haplotypes), and a relatively high African genetic component (12.66 $\pm$ 4.61 by ML; 10.26 of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {528--530}, }