% pubman genre = article @article{item_3257233, title = {{Genetic diversity of HLA system in seven populations from Veracruz, Mexico: Veracruz city, Coatzacoalcos, C{\'o}rdoba, Orizaba, Poza Rica, Xalapa and rural Veracruz}}, author = {Barquera, Rodrigo and L{\'o}pez-Gil, Concepci{\'o}n and Acu{\~n}a-Alonzo, V{\'\i}ctor and Vega-Mart{\'\i}nez, Mar{\'\i}a del Rosario and Rodr{\'\i}guez-Mungu{\'\i}a, Tirzo Jes{\'u}s and Mart{\'\i}nez-{\'A}lvarez, Julio C{\'e}sar and Arrieta-Bola{\~n}os, Esteban and Clayton, Stephen and la Cruz, Flor del Roc{\'\i}o Ramos-de and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and Bravo-Acevedo, Alicia and Ben{\'\i}tez-Arvizu, Gamaliel and Arrazola-Garc{\'\i}a, Mar{\'\i}a Araceli and Aquino-Rubio, Guadalupe and Ju{\'a}rez-Barreto, Vicencio and M{\'e}ndez-Mani, Patricia and V{\'a}zquez-Castillo, Tannya Ver{\'o}nica and Salgado-Galicia, Norma and Sol{\'\i}s-Mart{\'\i}nez, Ra{\'u}l and de Pav{\'o}n-Vargas, Mar{\'\i}a los {\'A}ngeles and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.07.292}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1113 Mexicans from the state of Veracruz living in the cities of Coatzacoalcos (N {\textequals} 55), Orizaba (N {\textequals} 60), C{\'o}rdoba (N {\textequals} 56), Poza Rica (N {\textequals} 45), Veracruz (N {\textequals} 171), Xalapa (N {\textequals} 187) and rural communities (N {\textequals} 539) to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes include 12 Native American haplotypes. Admixture estimates revealed that the main genetic components are Native American (64.93 $\pm$ 1.27 by ML; 55.10 of Native American haplotypes) and European (26.56 $\pm$ 0.89 by ML; 28.38 of European haplotypes), and a relatively high African genetic component (8.52 $\pm$ 1.82 by ML; 8.78 of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {531--534}, }