% pubman genre = article @article{item_3257234, title = {{Genetic diversity of HLA system in two populations from Campeche, Mexico: Campeche city and rural Campeche}}, author = {Barquera, Rodrigo and Lara-Riegos, Julio and Ponnendai-Shanmugavel, Komathi Sree and Immel, Alexander and Arrieta-Bola{\~n}os, Esteban and Clayton, Stephen and Sol{\'\i}s-Mart{\'\i}nez, Ra{\'u}l and Bravo-Acevedo, Alicia and V{\'a}zquez-Castillo, Tannya Ver{\'o}nica and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and Vega-Mart{\'\i}nez, Mar{\'\i}a del Rosario and Salgado-Galicia, Norma and Medina-Escobedo, Carolina Elizabeth and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.07.281}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 81 Mexicans from the state of Campeche living in the city of Campeche (N {\textequals} 34) and rural communities (N {\textequals} 47), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Campeche include ten Native American, three European, one African and one Asian haplotype. Admixture estimates revealed that the main genetic components in the state of Campeche are Native American (65.56 $\pm$ 0.96 by ML; 51.24 of Native American haplotypes), European (34.44 $\pm$ 10.94 by ML; 30.25 of European haplotypes), and a virtually absent African genetic component (0.00 $\pm$ 10.31 by ML; 9.26 of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {566--568}, }