% pubman genre = article @article{item_3257235, title = {{Genetic diversity of HLA system in two populations from Chiapas, Mexico: Tuxtla Guti{\'e}rrez and rural Chiapas}}, author = {Barquera, Rodrigo and Ju{\'a}rez-Nicol{\'a}s, Francisco and Mart{\'\i}nez-{\'A}lvarez, Julio C{\'e}sar and Ponnendai-Shanmugavel, Komathi Sree and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and V{\'a}zquez-Castillo, Tannya Ver{\'o}nica and Arrieta-Bola{\~n}os, Esteban and Clayton, Stephen and Sol{\'\i}s-Mart{\'\i}nez, Ra{\'u}l and Ortega-Y{\'a}{\~n}ez, Andrea and Arrazola-Garc{\'\i}a, Mar{\'\i}a Araceli and Immel, Alexander and Bravo-Acevedo, Alicia and Vega-Mart{\'\i}nez, Mar{\'\i}a del Rosario and Ben{\'\i}tez-Arvizu, Gamaliel and Garc{\'\i}a-{\'A}lvarez, Raquel and Mart{\'\i}nez-Bezies, Virginia and Escutia-Gonz{\'a}lez, Ariadna and Ju{\'a}rez-Barreto, Vicencio and Salgado-Galicia, Norma and Novelo-Garza, B{\'a}rbara and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.07.285}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 173 Mexicans from the state of Chiapas living in the city of Tuxtla Guti{\'e}rrez (N {\textequals} 52) and rural communities (N {\textequals} 121), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in Chiapas include 12 Native American and one European haplotype. Admixture estimates revealed that the main genetic components in Chiapas are Native American (71.61 $\pm$ 0.58 by ML; 53.16 of Native American haplotypes) and European (26.39 $\pm$ 5.05 by ML; 25.86 of European haplotypes), and a less prominent African genetic component (2.00 $\pm$ 5.20 by ML; 9.77 of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, number = {9}, pages = {563--565}, }