% pubman genre = article @article{item_3257238, title = {{Genetic diversity of HLA system in two populations from Yucat{\'a}n, Mexico: M{\'e}rida and rural Yucat{\'a}n}}, author = {Lara-Riegos, Julio and Barquera, Rodrigo and Castillo-Ch{\'a}vez, Oana del and Medina-Escobedo, Carolina Elizabeth and Hern{\'a}ndez-Zaragoza, Diana Ira{\'\i}z and Arrieta-Bola{\~n}os, Esteban and Clayton, Stephen and Ponnandai-Shanmugavel, Komathi Sree and Bravo-Acevedo, Alicia and Z{\'u}{\~n}iga, Joaqu{\'\i}n and Yunis, Edmond J. and Bekker-M{\'e}ndez, Carolina and Granados, Julio}, language = {eng}, issn = {0198-8859}, doi = {10.1016/j.humimm.2019.07.280}, publisher = {Elsevier}, address = {New York, N.Y.}, year = {2020}, date = {2020-09}, abstract = {{We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 324 Mexicans from the state of Yucat{\'a}n living in the city of M{\'e}rida (N {\textequals} 192) and rural communities (N {\textequals} 132), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in the state of Yucat{\'a}n include 16 Native American and one European haplotype. Admixture estimates revealed that the main genetic components in Yucat{\'a}n are Native American (81.54 $\pm$ 4.99{\textpercent} by ML; 62.92{\textpercent} of Native American haplotypes) and European (11.50 $\pm$ 15.43{\textpercent} by ML; 23.26{\textpercent} of European haplotypes), and a less prominent African genetic component (6.96 $\pm$ 10.47{\textpercent} by ML; 5.93{\textpercent} of African haplotypes).}}, journal = {{Human Immunology}}, volume = {81}, pages = {569--572}, }