% pubman genre = article
@article{item_3257253,
title = {{Dissecting the Pre-Columbian genomic ancestry of Native Americans along the Andes-Amazonia divide}},
author = {Gnecchi Ruscone, Guido Alberto and Sarno, Stefania and Fanti De, Sara and Gianvincenzo, Laura and Giuliani, Cristina and Boattini, Alessio and Bortolini, Eugenio and Corcia Di, Tullia and Mellado, Cesar Sanchez and Jesus, Taylor and Francia, D{\`a}vila and Gentilini, Davide and Blasio Di, Anna Maria and Cosimo Di, Patrizia and Cilli, Elisabetta and Gonzalez-Martin, Antonio and Franceschi, Claudio and Franceschi, Zelda Alice and Rickards, Olga and Sazzini, Marco and Luiselli, Donata and Pettener, Davide},
language = {eng},
issn = {0737-4038},
doi = {10.1093/molbev/msz066},
publisher = {Oxford University Press},
address = {Oxford},
year = {2019},
date = {2019-06},
abstract = {{Extensive European and African admixture coupled with loss of Amerindian lineages makes the reconstruction of pre-Columbian history of Native Americans based on present-day genomes extremely challenging. Still open questions remain about the dispersals that occurred throughout the continent after the initial peopling from the Beringia, especially concerning the number and dynamics of diffusions into South America. Indeed, if environmental and historical factors contributed to shape distinct gene pools in the Andes and Amazonia, the origins of this East-West genetic structure and the extension of further interactions between populations residing along this divide are still not well understood.To this end, we generated new high-resolution genome-wide data for 229 individuals representative of one Central and 10 South Amerindian ethnic groups from Mexico, Peru, Bolivia and Argentina. Low levels of European and African admixture in the sampled individuals allowed the application of fine-scale haplotype-based methods and demographic modeling approaches. These analyses revealed highly specific Native American genetic ancestries and great intra-group homogeneity, along with limited traces of gene flow mainly from the Andes into Peruvian Amazonians. Substantial amount of genetic drift differentially experienced by the considered populations underlined distinct patterns of recent inbreeding or prolonged isolation. Overall, our results support the hypothesis that all non-Andean South Americans are compatible with descending from a common lineage, while we found low support for common Mesoamerican ancestors of both Andeans and other South American groups. These findings suggest extensive back-migrations into Central America from non-Andean sources or conceals distinct peopling events into the Southern Continent.}},
journal = {{Molecular Biology and Evolution}},
volume = {36},
number = {6},
pages = {1254--1269},
eid = {msz066},
}