% pubman genre = article @article{item_3266570, title = {{BEAST 2.5: An advanced software platform for Bayesian evolutionary analysis}}, author = {Bouckaert, Remco and Vaughan, Timothy G. and Barido-Sottani, Joelle and Duch{\^e}ne, Sebasti{\'a}n and Fourment, Mathieu and Gavryushkina, Alexandra and Heled, Joseph and Jones, Graham and K{\"u}hnert, Denise and De Maio, Nicola and Matschiner, Michael and Mendes, F{\'a}bio K. and M{\"u}ller, Nicola F. and Ogilvie, Huw A. and du Plessis, Louis and Popinga, Alex and Rambaut, Andrew and Rasmussen, David and Siveroni, Igor and Suchard, Marc A. and Wu, Chieh-Hsi and Xie, Dong and Zhang, Chi and Stadler, Tanja and Drummond, Alexei J.}, language = {eng}, issn = {1553-734X}, doi = {10.1371/journal.pcbi.1006650}, publisher = {Public Library of Science}, address = {San Francisco, CA}, year = {2019}, abstract = {{Elaboration of Bayesian phylogenetic inference methods has continued at pace in recent years with major new advances in nearly all aspects of the joint modelling of evolutionary data. It is increasingly appreciated that some evolutionary questions can only be adequately answered by combining evidence from multiple independent sources of data, including genome sequences, sampling dates, phenotypic data, radiocarbon dates, fossil occurrences, and biogeographic range information among others. Including all relevant data into a single joint model is very challenging both conceptually and computationally. Advanced computational software packages that allow robust development of compatible (sub-)models which can be composed into a full model hierarchy have played a key role in these developments. Developing such software frameworks is increasingly a major scientific activity in its own right, and comes with specific challenges, from practical software design, development and engineering challenges to statistical and conceptual modelling challenges. BEAST 2 is one such computational software platform, and was first announced over 4 years ago. Here we describe a series of major new developments in the BEAST 2 core platform and model hierarchy that have occurred since the first release of the software, culminating in the recent 2.5 release.}}, journal = {{PLoS Computational Biology}}, volume = {15}, number = {4}, eid = {e1006650}, }