% pubman genre = article @article{item_3324033, title = {{The long lives of primates and the {\textquoteleft}invariant rate of ageing{\textquoteright} hypothesis}}, author = {Colchero, Fernando and Aburto, Jos{\'e} and Archie, Elizabeth and Boesch, Christophe and Breuer, Thomas and Campos, Fernando and Collins, Anthony and Conde, Dalia and Cords, Marina and Crockford, Catherine and Thompson, Melissa Emery and Fedigan, Linda and Fichtel, Claudia and Groenenberg, Milou and Hobaiter, Catherine and Kappeler, Peter and Lawler, Richard and Lewis, Rebecca and Machanda, Zarin and Manguette, Marie and Muller, Martin and Packer, Craig and Parnell, Richard and Perry, Susan and Pusey, Anne and Robbins, Martha M. and Seyfarth, Robert and Silk, Joan and Staerk, Johanna and Stoinski, Tara and Stokes, Emma and Strier, Karen and Strum, Shirley and Tung, Jenny and Villavicencio, Francisco and Wittig, Roman M. and Wrangham, Richard and Zuberb{\"u}hler, Klaus and Vaupel, James and Alberts, Susan}, language = {eng}, doi = {10.1038/s41467-021-23894-3}, publisher = {Nature}, year = {2021}, abstract = {{Is it possible to slow the rate of ageing, or do biological constraints limit its plasticity? We test the {\textquoteleft}invariant rate of ageing{\textquoteright} hypothesis, which posits that the rate of ageing is relatively fixed within species, with a collection of 39 human and nonhuman primate datasets across seven genera. We first recapitulate, in nonhuman primates, the highly regular relationship between life expectancy and lifespan equality seen in humans. We next demonstrate that variation in the rate of ageing within genera is orders of magnitude smaller than variation in pre-adult and age-independent mortality. Finally, we demonstrate that changes in the rate of ageing, but not other mortality parameters, produce striking, species-atypical changes in mortality patterns. Our results support the invariant rate of ageing hypothesis, implying biological constraints on how much the human rate of ageing can be slowed.}}, journal = {{Nature Communications}}, volume = {12}, eid = {3666}, }