% pubman genre = article
@article{item_3339789,
title = {{Leprosy in wild chimpanzees}},
author = {Hockings, K.J. and Mubemba, B. and Avanzi, C. and Pleh, K. and D{\"u}x, A. and Bersacola, E. and Bessa, J. and Ramon, M. and Metzger, S. and Patrono, L.V. and Jaffe, J.E. and Benjak, A. and Bonneaud, C. and Busso, P. and Couacy-Hymann, E. and Gado, M. and Gagneux, S. and Johnson, R.C. and Kodio, M. and Lynton-Jenkins, J. and Morozova, I. and M{\"a}tz-Rensing, K. and Regalla, A. and Said, A.R. and Schuenemann, V.J. and Sow, S.O. and Spencer, J.S. and Ulrich, M. and Zoubi, H. and Cole, S.T. and Wittig, Roman M. and Calvignac-Spencer, S. and Leendertz, Fabian H.},
language = {eng},
issn = {0028-0836},
doi = {10.1038/s41586-021-03968-4},
publisher = {Nature Publishing Group},
address = {London},
year = {2021},
date = {2021},
abstract = {{Humans are considered as the main host for Mycobacterium leprae1, the aetiological agent of leprosy, but spillover has occurred to other mammals that are now maintenance hosts, such as nine-banded armadillos and red squirrels2,3. Although naturally acquired leprosy has also been described in captive nonhuman primates4,5,6,7, the exact origins of infection remain unclear. Here we describe leprosy-like lesions in two wild populations of western chimpanzees (Pan troglodytes verus) in Cantanhez National Park, Guinea-Bissau and Ta{\"\i} National Park, C{\^o}te d{\textquoteright}Ivoire, West Africa. Longitudinal monitoring of both populations revealed the progression of disease symptoms compatible with advanced leprosy. Screening of faecal and necropsy samples confirmed the presence of M. leprae as the causative agent at each site and phylogenomic comparisons with other strains from humans and other animals show that the chimpanzee strains belong to different and rare genotypes (4N/O and 2F). These findings suggest that M. leprae may be circulating in more wild animals than suspected, either as a result of exposure to humans or other unknown environmental sources.}},
journal = {{Nature}},
volume = {598},
pages = {652--656},
}