% pubman genre = article @article{item_3346696, title = {{Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes}}, author = {Pfrengle, Saskia and Neukamm, Judith and Guellil, Meriam and Keller, Marcel and Molak, Martyna and Avanzi, Charlotte and Kushniarevich, Alena and Montes, N{\'u}ria and Neumann, Gunnar U. and Reiter, Ella and Tukhbatova, Rezeda I. and Berezina, Nataliya Y. and Buzhilova, Alexandra P. and Korobov, Dmitry S. and Suppersberger Hamre, Stian and Matos, Vitor M. J. and Ferreira, Maria T. and Gonz{\'a}lez-Garrido, Laura and Wasterlain, Sofia N. and Lopes, C{\'e}lia and Santos, Ana Luisa and Antunes-Ferreira, Nathalie and Duarte, Vit{\'o}ria and Silva, Ana Maria and Melo, Linda and Sarkic, Natasa and Saag, Lehti and Tambets, Kristiina and Busso, Philippe and Cole, Stewart T. and Avlasovich, Alexei and Roberts, Charlotte A. and Sheridan, Alison and Cessford, Craig and Robb, John and Krause, Johannes and Scheib, Christiana L. and Inskip, Sarah A. and Schuenemann, Verena J.}, language = {eng}, isbn = {1741-7007}, doi = {10.1186/s12915-021-01120-2}, year = {2021}, abstract = {{Hansen{\textquoteright}s disease (leprosy), widespread in medieval Europe, is today mainly prevalent in tropical and subtropical regions with around 200,000 new cases reported annually. Despite its long history and appearance in historical records, its origins and past dissemination patterns are still widely unknown. Applying ancient DNA approaches to its major causative agent, Mycobacterium leprae, can significantly improve our understanding of the disease{\textquoteright}s complex history. Previous studies have identified a high genetic continuity of the pathogen over the last 1500 years and the existence of at least four M. leprae lineages in some parts of Europe since the Early Medieval period.}}, journal = {{BMC Biology}}, volume = {19}, eid = {220}, }