% pubman genre = article
@article{item_3366884,
title = {{Genomic basis for skin phenotype and cold adaptation in the extinct Steller{\textquoteright}s sea cow}},
author = {Le Duc, Diana and Velluva, Akhil and Cassatt-Johnstone, Molly and Olsen, Remi-Andre and Baleka, Sina and Lin, Chen-Ching and Lemke, Johannes R. and Southon, John R. and Burdin, Alexander and Wang, Ming-Shan and Grunewald, Sonja and Rosendahl, Wilfried and Joger, Ulrich and Rutschmann, Sereina and Hildebrandt, Thomas B. and Fritsch, Guido and Estes, James A. and Kelso, Janet and Dal{\'e}n, Love and Hofreiter, Michael and Shapiro, Beth and Sch{\"o}neberg, Torsten},
language = {eng},
issn = {2375-2548},
doi = {10.1126/sciadv.abl6496},
publisher = {American Association for the Advancement of Science (AAAS)},
year = {2022},
abstract = {{Steller{\textquoteright}s sea cow, an extinct sirenian and one of the largest Quaternary mammals, was described by Georg Steller in 1741 and eradicated by humans within 27 years. Here, we complement Steller{\textquoteright}s descriptions with paleogenomic data from 12 individuals. We identified convergent evolution between Steller{\textquoteright}s sea cow and cetaceans but not extant sirenians, suggesting a role of several genes in adaptation to cold aquatic (or marine) environments. Among these are inactivations of lipoxygenase genes, which in humans and mouse models cause ichthyosis, a skin disease characterized by a thick, hyperkeratotic epidermis that recapitulates Steller{\textquoteright}s sea cows{\textquoteright} reportedly bark-like skin. We also found that Steller{\textquoteright}s sea cows{\textquoteright} abundance was continuously declining for tens of thousands of years before their description, implying that environmental changes also contributed to their extinction.}},
journal = {{Science Advances}},
volume = {8},
number = {5},
}