% pubman genre = article
@article{item_3371846,
title = {{Geographically dispersed zoonotic tuberculosis in pre-contact South American human populations}},
author = {Vagene, Ashild J and Honap, Tanvi P. and Harkins, Kelly M. and Rosenberg, Michael S. and Giffin, Karen and C{\'a}rdenas-Arroyo, Felipe and Leguizam{\'o}n, Laura Paloma and Arnett, Judith and Buikstra, Jane E. and Herbig, Alexander and Krause, Johannes and Stone, Anne C. and Bos, Kirsten I.},
language = {eng},
issn = {2041-1723},
doi = {10.1038/s41467-022-28562-8},
year = {2022},
abstract = {{Previous ancient DNA research has shown that Mycobacterium pinnipedii, which today causes{\textless}br{\textgreater}tuberculosis (TB) primarily in pinnipeds, infected human populations living in the coastal{\textless}br{\textgreater}areas of Peru prior to European colonization. Skeletal evidence indicates the presence of TB in{\textless}br{\textgreater}several pre-colonial South and North American populations with minimal access to marine{\textless}br{\textgreater}resources{\textemdash} a scenario incompatible with TB transmission directly from infected pinnipeds or{\textless}br{\textgreater}their tissues. In this study, we investigate the causative agent of TB in ten pre-colonial, non-{\textless}br{\textgreater}coastal individuals from South America. We reconstruct M. pinnipedii genomes (10- to 15-fold{\textless}br{\textgreater}mean coverage) from three contemporaneous individuals from inland Peru and Colombia,{\textless}br{\textgreater}demonstrating the widespread dissemination of M. pinnipedii beyond the coast, either through{\textless}br{\textgreater}human-to-human and/or animal-mediated routes. Overall, our study suggests that TB{\textless}br{\textgreater}transmission in the pre-colonial era Americas involved a more complex transmission pathway{\textless}br{\textgreater}than simple pinniped-to-human transfer.}},
journal = {{Nature Communications}},
volume = {13},
eid = {1195},
}