% pubman genre = article @article{item_3375973, title = {{Non{-}invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capture}}, author = {Patrono, Livia V. and R{\"o}themeier, Caroline and Kouadio, Leonce and Couacy{-}Hymann, Emmanuel and Wittig, Roman M. and Calvignac{-}Spencer, S{\'e}bastien and Leendertz, Fabian H.}, language = {eng}, issn = {1750-2640; 1750-2659}, doi = {10.1111/irv.12984}, publisher = {Wiley}, year = {2022}, date = {2022-09}, abstract = {{Human respiratory pathogens have repeatedly caused lethal outbreaks in wild great {\textless}br{\textgreater}{\textless}br{\textgreater}apes across Africa, leading to population declines. Nonetheless, our knowledge of {\textless}br{\textgreater}{\textless}br{\textgreater}potential genomic changes associated with pathogen introduction and spread at the {\textless}br{\textgreater}{\textless}br{\textgreater}human-great ape interface remains sparse. Here, we made use of target enrichment {\textless}br{\textgreater}{\textless}br{\textgreater}coupled with next generation sequencing to non-invasively investigate five outbreaks {\textless}br{\textgreater}{\textless}br{\textgreater}of human-introduced respiratory disease in wild chimpanzees living in Ta{\"\i} National {\textless}br{\textgreater}{\textless}br{\textgreater}Park, Ivory Coast. By retrieving 34 complete viral genomes and three distinct {\textless}br{\textgreater}{\textless}br{\textgreater}constellations of pneumococcal virulence factors, we provide genomic insights into {\textless}br{\textgreater}{\textless}br{\textgreater}these spillover events and describe a framework for non-invasive genomic {\textless}br{\textgreater}{\textless}br{\textgreater}surveillance in wildlife.}}, journal = {{Influenza and Other Respiratory Viruses}}, volume = {16}, number = {5}, pages = {858--861}, eid = {12984}, }