% pubman genre = article @article{item_3430131, title = {{The Anglo-Saxon migration and the formation of the early English gene pool}}, author = {Gretzinger, Joscha and Sayer, Duncan and Justeau, Pierre and Altena, Eveline and Pala, Maria and Dulias, Katharina and Edwards, Ceiridwen J. and Jodoin, Susanne and Lacher, Laura and Sabin, Susanna and V{\aa}gene, {\AA}shild J. and Haak, Wolfgang and Ebenesersd{\'o}ttir, S. Sunna and Moore, Kristjan H. S. and Radzeviciute, Rita and Schmidt, Kara and Brace, Selina and Bager, Martina Abenhus and Patterson, Nick and Papac, Luka and Broomandkhoshbacht, Nasreen and Callan, Kimberly and Harney, {\'E}adaoin and Iliev, Lora and Lawson, Ann Marie and Michel, Megan and Stewardson, Kristin and Zalzala, Fatma and Rohland, Nadin and Kappelhoff-Beckmann, Stefanie and Both, Frank and Winger, Daniel and Neumann, Daniel and Saalow, Lars and Krabath, Stefan and Beckett, Sophie and Van Twest, Melanie and Faulkner, Neil and Read, Chris and Barton, Tabatha and Caruth, Joanna and Hines, John and Krause-Kyora, Ben and Warnke, Ursula and Schuenemann, Verena J. and Barnes, Ian and Dahlstr{\"o}m, Hanna and Clausen, Jane Jark and Richardson, Andrew and Popescu, Elizabeth and Dodwell, Natasha and Ladd, Stuart and Phillips, Tom and Mortimer, Richard and Sayer, Faye and Swales, Diana and Stewart, Allison and Powlesland, Dominic and Kenyon, Robert and Ladle, Lilian and Peek, Christina and Grefen-Peters, Silke and Ponce, Paola and Daniels, Robin and Spall, Cecily and Woolcock, Jennifer and Jones, Andy M. and Roberts, Amy V. and Symmons, Robert and Rawden, Anooshka C. and Cooper, Alan and Bos, Kirsten I. and Booth, Tom and Schroeder, Hannes and Thomas, Mark G. and Helgason, Agnar and Richards, Martin B. and Reich, David and Krause, Johannes and Schiffels, Stephan}, language = {eng}, issn = {0028-0836; 1476-4687}, doi = {10.1038/s41586-022-05247-2}, year = {2022}, date = {2022}, abstract = {{The history of the British Isles and Ireland is characterized by multiple periods of {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}major cultural change, including the influential transformation after the end of {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}Roman rule, which precipitated shifts in language, settlement patterns and material {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}culture1. The extent to which migration from continental Europe mediated these {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}transitions is a matter of long-standing debate2{\textendash}4. Here we study genome-wide ancient {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}DNA from 460 medieval northwestern Europeans{\textemdash}including 278 individuals from {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}England{\textemdash}alongside archaeological data, to infer contemporary population dynamics. {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}We identify a substantial increase of continental northern European ancestry in early {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}medieval England, which is closely related to the early medieval and present-day {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}inhabitants of Germany and Denmark, implying large-scale substantial migration {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}across the North Sea into Britain during the Early Middle Ages. As a result, the {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}individuals who we analysed from eastern England derived up to 76{\textpercent} of their ancestry {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}from the continental North Sea zone, albeit with substantial regional variation and {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}heterogeneity within sites. We show that women with immigrant ancestry were more {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}often furnished with grave goods than women with local ancestry, whereas men with {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}weapons were as likely not to be of immigrant ancestry. A comparison with present-{\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}day Britain indicates that subsequent demographic events reduced the fraction of {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}continental northern European ancestry while introducing further ancestry {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}components into the English gene pool, including substantial southwestern {\textless}br{\textgreater}{\textless}br{\textgreater}{\textless}br{\textgreater}European ancestry most closely related to that seen in Iron Age France}}, journal = {{Nature}}, volume = {610}, pages = {112--119}, }