% pubman genre = article
@article{item_3525092,
title = {{High-coverage genome of the Tyrolean Iceman reveals unusually high Anatolian farmer ancestry}},
author = {Wang, Ke and Pr{\"u}fer, Kay and Krause-Kyora, Ben and Childebayeva, Ainash and Schuenemann, Verena J. and Coia, Valentina and Maixner, Frank and Zink, Albert and Schiffels, Stephan and Krause, Johannes},
language = {eng},
issn = {2666979X},
doi = {10.1016/j.xgen.2023.100377},
year = {2023},
date = {2023-09-13},
abstract = {{The Tyrolean Iceman is known as one of the oldest human glacier mummies, directly dated to 3350{\textendash}3120 calibrated BCE. A previously published low-coverage genome provided novel insights into European prehistory, despite high present-day DNA contamination. Here, we generate a high-coverage genome with low contamination (15.3$\times$) to gain further insights into the genetic history and phenotype of this individual. Contrary to previous studies, we found no detectable Steppe-related ancestry in the Iceman. Instead, he retained the highest Anatolian-farmer-related ancestry among contemporaneous European populations, indicating a rather isolated Alpine population with limited gene flow from hunter-gatherer-ancestry-related populations. Phenotypic analysis revealed that the Iceman likely had darker skin than present-day Europeans and carried risk alleles associated with male-pattern baldness, type 2 diabetes, and obesity-related metabolic syndrome. These results corroborate phenotypic observations of the preserved mummified body, such as high pigmentation of his skin and the absence of hair on his head.}},
journal = {{Cell Genomics}},
volume = {3},
number = {9},
eid = {100377},
}