% pubman genre = article
@article{item_3641640,
title = {{Convergent evolution of complex adaptive traits modulates angiogenesis in high-altitude Andean and Himalayan human populations}},
author = {Ferraretti, Giulia and Rill, Aina and Abondio, Paolo and Smith, Kyra and Ojeda-Granados, Claudia and De Fanti, Sara and Alberti, Marta and Izzi, Massimo and Sherpa, Phurba T. and Cocco, Paolo and Tiriticco, Massimiliano and Di Marcello, Marco and Dezi, Agnese and Gnecchi-Ruscone, Guido Alberto and Natali, Luca and Corcelli, Angela and Marinelli, Giorgio and Garagnani, Paolo and Peluzzi, Davide and Luiselli, Donata and Pettener, Davide and Sarno, Stefania and Sazzini, Marco},
language = {eng},
issn = {2399-3642},
doi = {10.1038/s42003-025-07813-6},
publisher = {Springer Nature},
address = {London},
year = {2025},
date = {2025},
abstract = {{Convergent adaptations represent paradigmatic examples of the capacity of natural selection to influence organisms{\textquoteright} biology. However, the possibility to investigate the genetic determinants underpinning convergent complex adaptive traits has been offered only recently by methods for inferring polygenic adaptations from genomic data. Relying on this approach, we demonstrate how high-altitude Andean human groups experienced pervasive selective events at angiogenic pathways, which resemble those previously attested for Himalayan populations despite partial convergence at the single-gene level was observed. This provides additional evidence for the drivers of convergent evolution of enhanced blood perfusion in populations exposed to hypobaric hypoxia for thousands of years.}},
journal = {{Communications Biology}},
volume = {8},
eid = {377},
}