% pubman genre = article
@article{item_3669544,
title = {{Bone adhered sediments as a source of target and environmental DNA and proteins}},
author = {de-Dios, Toni and Bonucci, Biancamaria and Barbieri, R{\'e}mi and Kushniarevich, Alena and D{\textquoteright}Atanasio, Eugenia and Dittmar, Jenna and Cessford, Craig and Solnik, Anu and Robb, John E and Warinner, Christina and Oras, Ester and Scheib, Christiana L},
language = {eng},
issn = {0737-4038},
doi = {10.1093/molbev/msaf202},
publisher = {Oxford University Press},
address = {Oxford},
year = {2025},
date = {2025-09},
abstract = {{In recent years, sediments from cave environments have provided invaluable insights into ancient hominids, as well as past fauna and flora. Unfortunately, however, sediments are not always collected during excavation. In this study, we analyzed an overlooked but abundant resource in archaeological collections - sediments adhered to bone. We performed metagenomics and metaproteomics analysis on sediment from several human skeletal elements, originating from Neolithic to Medieval sites in England. We were able to reconstruct a partial human genome, the genetic profile of which matches that recovered from the original skeletal element. Additionally, aDNA sequences matching the genomes of endogenous gut microbiome bacteria were identified. We also found the presence of genetic sequences corresponding to animals and plants. In particular, we managed to retrieve the partial genome and proteome of a Black Rat (Rattus rattus), sharing close genetic affinities to other medieval Rattus rattus. Our results demonstrate that material that is usually ignored or discarded, can be used to reveal information about the individual and the environmental conditions at the time of their death.}},
journal = {{Molecular Biology and Evolution}},
volume = {42},
number = {9},
eid = {msaf202},
}