%0 Journal Article %A Slon, Viviane %A Hopfe, Charlotte %A Weiß, Clemens L. %A Mafessoni, Fabrizio %A de la Rasilla, Marco %A Lalueza-Fox, Carles %A Rosas, Antonio %A Soressi, Marie %A Knul, Monika V. %A Miller, Rebecca %A Stewart, John R. %A Derevianko, Anatoly P. %A Jacobs, Zenobia %A Li, Bo %A Roberts, Richard G. %A Shunkov, Michael V. %A de Lumley, Henry %A Perrenoud, Christian %A Gušic, Ivan %A Kucan, Željko %A Rudan, Pavao %A Ayinuer-Petri, Aximu %A Essel, Elena %A Nagel, Sarah %A Nickel, Birgit %A Schmidt, Anna %A Prüfer, Kay %A Kelso, Janet %A Burbano, Hernán A. %A Pääbo, Svante %A Meyer, Matthias %+ Neandertals and more, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Genomes, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society The Minerva Research Group for Bioinformatics, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Neandertals and more, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society %T Neandertal and Denisovan DNA from Pleistocene sediments : %G eng %U https://hdl.handle.net/11858/00-001M-0000-002D-26B8-A %R 10.1126/science.aam9695 %7 2017-04-27 %D 2017 %8 12.05.2017 %* Review method: peer-reviewed %X Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples we detect Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility to detect the presence of hominin groups at sites and in areas where no skeletal remains are found. %J Science %V 356 %N 6338 %& 605 %P 605 - 608 %I American Association for the Advancement of Science %C Washington, D.C. %@ 0036-8075