%0 Book Section %A Stoneking, Mark %+ Human Population History, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society %T Mitochondrial DNA : %G eng %U https://hdl.handle.net/21.11116/0000-0003-16A0-F %R 10.1002/9781118584538.ieba0322 %D 2018 %* Review method: internal %X Mitochondrial DNA (mtDNA) is the only DNA found outside the nucleus of the cell. It has a number of useful properties for anthropological studies, including a rapid rate of evolution, maternal mode of inheritance, and being present in hundreds to thousands of copies per cell. Despite being a single genetic locus, mtDNA has contributed enormously to anthropology: it provided the first compelling genetic evidence that favored a recent African origin of our species; when combined with studies of the paternally inherited Y-chromosome, it provides insights into sex-specific features of human populations; and it is particularly useful in studies of ancient DNA. %K Human origins; migration; sex-biased admixture; ancient DNA %B The International Encyclopedia of Biological Anthropology %E Trevathan, Wenda %V 2 %P 1020 - 1023 %I Wiley %C Hoboken, New Jersey %@ 9781118584538