%0 Journal Article %A Shinde, Vasant %A Narasimhan, Vagheesh M. %A Rohland, Nadin %A Mallick, Swapan %A Mah, Matthew %A Lipson, Mark %A Nakatsuka, Nathan %A Adamski, Nicole %A Broomandkhoshbacht, Nasreen %A Ferry, Matthew %A Lawson, Ann Marie %A Michel, Megan %A Oppenheimer, Jonas %A Stewardson, Kristin %A Jadhav, Nilesh %A Kim, Yong Jun %A Chatterjee, Malavika %A Munshi, Avradeep %A Panyam, Amrithavalli %A Waghmare, Pranjali %A Yadav, Yogesh %A Patel, Himani %A Kaushik, Amit %A Thangaraj, Kumarasamy %A Meyer, Matthias %A Patterson, Nick %A Rai, Niraj %A Reich, David %+ Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society %T An ancient Harappan genome lacks ancestry from Steppe pastoralists or Iranian farmers : %G eng %U https://hdl.handle.net/21.11116/0000-0004-F535-C %R 10.1016/j.cell.2019.08.048 %D 2019 %8 17.10.2019 %* Review method: peer-reviewed %X Summary
We report an ancient genome from the Indus Valley Civilization (IVC). The individual we sequenced fits as a mixture of people related to ancient Iranians (the largest component) and Southeast Asian hunter-gatherers, a unique profile that matches ancient DNA from 11 genetic outliers from sites in Iran and Turkmenistan in cultural communication with the IVC. These individualsĀ had little if any Steppe pastoralist-derived ancestry, showing that it was not ubiquitous in northwest South Asia during the IVC as it is today. The Iranian-related ancestry in the IVC derives from a lineage leading to early Iranian farmers, herders, and hunter-gatherers before their ancestors separated, contradicting the hypothesis that the shared ancestry between early Iranians and South Asians reflects a large-scale spread of western Iranian farmers east. Instead, sampled ancient genomes from the Iranian plateau and IVC descend from different groups of hunter-gatherers who began farming without being connected by substantial movement of people. %K population genetics, archaeology, anthropology, South Asia, Indus Valley Civilization, Harappan Civilization, ancient DNA %J Cell %V 179 %N 3 %& 729 %P 729 - 735.e10 %@ 0092-8674