%0 Journal Article
%A Traversari, Mirko
%A Da Via, Silvia
%A Petrella, Enrico
%A Feeney, Robin N.M.
%A Benazzi, Stefano
%+ Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
%T A case of dwarfism in 6th century Italy: Bioarchaeological assessment of a hereditary disorder : 
%G eng
%U https://hdl.handle.net/21.11116/0000-0006-FAC7-0
%R 10.1016/j.ijpp.2020.03.003
%D 2020
%* Review method: peer-reviewed
%X Objective<br>The skeletal remains of a short-statured individual (T17) are described and a differential diagnosis performed to determine the etiology of the condition.<br>Materials<br>An individual considered pathologically short in stature was discovered in the burial site of Piazza XX Settembre, Modena (northern Italy).<br>Methods<br>Morphological and morphometric analyses were performed, and T17 was compared to dwarfs from other localities and periods and to the adult female population from the same site. A paleopathological survey was undertaken to assess the degree of the skeletal elements of T17 were affected.<br>Results<br>T17 was a female, 20–30 years of age at death, with a stature of 128 cm and disproportionate dwarfism associated with congenital skeletal dysplasia.<br>Conclusions<br>T17 likely affected by a form of hypochondroplasia.<br>Significance<br>Anatomical consequences of hypochondroplasia are presented, and the timeframe and associated burial goods suggest a 6th-century Lombard short stature belonging to one of the earliest Lombard settlements in Italy.<br>Suggestions for further research<br>Future genetic analysis would resolve if the mutation in the type 3 fibroblast growth factor receptor (FGFR3) is present in the remains of T17; however, it is not exclusivly linked to hypochondroplasia.
%K Dwarfism; Hypochondroplasia;  Achondroplasia; Skeletal dysplasia
%J International Journal of Paleopathology
%V 30
%& 110
%P 110 - 117
%I Elsevier
%@ 1879-9817