%0 Journal Article %A Juárez-Nicolás, Francisco %A Barquera, Rodrigo %A Martínez-Álvarez, Julio César %A Hernández-Zaragoza, Diana Iraíz %A Ortega-Yáñez, Andrea %A Arrieta-Bolaños, Esteban %A Clayton, Stephen %A Bravo-Acevedo, Alicia %A Arrazola-García, María Araceli %A Immel, Alexander %A Juárez-Barreto, Vicencio %A Benítez-Arvizu, Gamaliel %A Vega-Martínez, María del Rosario %A García-Álvarez, Raquel %A Martínez-Bezies, Virginia %A Escutia-González, Ariadna Berenice %A Díaz-López, Rosario %A Guizar-López, Gregorio Ulises %A Salgado-Galicia, Norma %A Zúñiga, Joaquín %A Yunis, Edmond J. %A Bekker-Méndez, Carolina %A Granados, Julio %+ Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society %T Genetic diversity of HLA system in a population from Guerrero, Mexico : %G eng %U https://hdl.handle.net/21.11116/0000-0007-2FB5-9 %R 10.1016/j.humimm.2019.05.015 %F OTHER: 2241 %7 2019-06-04 %D 2020 %* Review method: peer-reviewed %X We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 144 Mexicans from the state of Guerrero to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in the state of Guerrero include eight Native American and two European haplotypes. Admixture estimates revealed that the main genetic components in the state of Guerrero are Native American (61.36 ± 2.69 by ML; 54.17 of Native American haplotypes) and European (35.01 ± 4.59 by ML; 32.29 of European haplotypes), and a relatively low African genetic component (3.63 ± 2.38 by ML; 5.90 of African haplotypes). %K HLA, Immunogenetics, Population genetics, Guerrero, Admixture %J Human Immunology %V 81 %N 9 %& 550 %P 550 - 552 %I Elsevier %C New York, N.Y. %@ 0198-8859