%0 Journal Article
%A Barquera, Rodrigo
%A Martínez-Álvarez, Julio César
%A Hernández-Zaragoza, Diana Iraíz
%A Bravo-Acevedo, Alicia
%A Juárez-Nicolás, Francisco
%A Arriaga-Perea, Agustín Jericó
%A Vega-Martínez, María del Rosario
%A Ortega-Yáñez, Andrea
%A Benítez-Arvizu, Gamaliel
%A Arrieta-Bolaños, Esteban
%A Clayton, Stephen
%A Juárez-Cortés, Eva Dolores
%A López-Gil, Concepción
%A García-Álvarez, Raquel
%A Arrazola-García, María Araceli
%A Martínez-Bezies, Virginia
%A Juárez-Barreto, Vicencio
%A la Cruz, Flor del Rocío Ramos-de
%A Macías-Medrano, Rosa María
%A Méndez-Mani, Patricia
%A Escutia-González, Ariadna
%A Montiel-Hernández, Gustavo Daniel
%A Immel, Alexander
%A de Pavón-Vargas, María los Ángeles
%A Salgado-Galicia, Norma
%A Novelo-Garza, Bárbara
%A Zúñiga, Joaquín
%A Yunis, Edmond J.
%A Bekker-Méndez, Carolina
%A Granados, Julio
%+ Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
%T Genetic diversity of HLA system in six populations from Mexico City Metropolitan Area, Mexico: Mexico City North, Mexico City South, Mexico City East, Mexico City West, Mexico City Center and rural Mexico City : 
%G eng
%U https://hdl.handle.net/21.11116/0000-0007-2F3E-1
%R 10.1016/j.humimm.2019.07.297
%F OTHER: shh2299
%7 2019-07-25
%D 2020
%* Review method: peer-reviewed
%X We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1217 Mexicans from the Mexico City Metropolitan Area living in the northern (N = 751), southern (N = 52), eastern (N = 79), western (N = 33), and central (N = 152) Mexico City, and rural communities (N = 150), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes include 11 Native American haplotypes. Admixture estimates revealed that the main genetic components are Native American (63.85 ± 1.55 by ML; 57.19 of Native American haplotypes) and European (28.53 ± 3.13 by ML; 28.40 of European haplotypes), and a less apparent African genetic component (7.61 ± 1.96 by ML; 7.17 of African haplotypes).
%K HLA, Immunogenetics, Population genetics, Mexico City, Mexico City Metropolitan Area, Admixture
%J Human Immunology
%V 81
%N 9
%& 539
%P 539 - 543
%I Elsevier
%C New York, N.Y.
%@ 0198-8859