%0 Journal Article
%A Hernández-Hernández, Ofelia
%A Hernández-Zaragoza, Diana Iraíz
%A Barquera, Rodrigo
%A Warinner, Christina G.
%A López-Gil, Concepción
%A Arrieta-Bolaños, Esteban
%A Clayton, Stephen
%A Bravo-Acevedo, Alicia
%A la Cruz, Flor del Rocío Ramos-de
%A Méndez-Mani, Patricia
%A de Pavón-Vargas, María los Ángeles
%A Zúñiga, Joaquín
%A Yunis, Edmond J.
%A Bekker-Méndez, Carolina
%A Granados, Julio
%+ Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Kostbare Kulturen, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
%T Genetic diversity of HLA system in two populations from Oaxaca, Mexico: Oaxaca city and rural Oaxaca : 
%G eng
%U https://hdl.handle.net/21.11116/0000-0007-2F9B-7
%R 10.1016/j.humimm.2019.07.278
%F OTHER: shh2315
%7 2019-07-22
%D 2020
%* Review method: peer-reviewed
%X We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 636 Mexicans from the state of Oaxaca living in the city of Oaxaca (N = 151) and rural communities (N = 485), to obtain information regarding allelic and haplotypic frequencies. We found that the 13 most frequent haplotypes in Oaxaca are all of putative Native American origin. Admixture estimates revealed that the main genetic components in the state of Oaxaca are Native American (73.12 ± 2.77 by ML; 61.52 of Native American haplotypes) and European (17.36 ± 2.07 by ML; 20.69 of European haplotypes), and a relatively high African genetic component (9.52 ± 0.88 by ML; 8.94 of African haplotypes).
%K HLA, Immunogenetics, Population genetics, Oaxaca, Admixture
%J Human Immunology
%V 81
%N 9
%& 553
%P 553 - 556
%I Elsevier
%C New York, N.Y.
%@ 0198-8859