%0 Journal Article
%A Barquera, Rodrigo
%A Martínez-Álvarez, Julio César
%A Trejo-Ordoz, Alondra Victoria
%A de Pavón-Vargas, María los Ángeles
%A Vega-Martínez, María del Rosario
%A Arrieta-Bolaños, Esteban
%A Clayton, Stephen
%A Ortega-Yáñez, Andrea
%A Juárez-Cortés, Eva Dolores
%A Juárez-Nicolás, Francisco
%A López-Gil, Concepción
%A Immel, Alexander
%A Arrazola-García, María Araceli
%A Juárez-Barreto, Vicencio
%A Benítez-Arvizu, Gamaliel
%A Arriaga-Perea, Agustín Jericó
%A Martínez-Bezies, Virginia
%A Macías-Medrano, Rosa María
%A la Cruz, Flor del Rocío Ramos-de
%A Hernández-Zaragoza, Diana Iraíz
%A Bravo-Acevedo, Alicia
%A Méndez-Mani, Patricia
%A Escutia-González, Ariadna Berenice
%A Montiel-Hernández, Gustavo Daniel
%A García-Álvarez, Raquel
%A Salgado-Galicia, Norma
%A Novelo-Garza, Bárbara
%A Zúñiga, Joaquín
%A Yunis, Edmond J.
%A Bekker-Méndez, Carolina
%A Granados, Julio
%+ Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
%T Genetic diversity of HLA system in two populations from Hidalgo, Mexico: Pachuca and rural Hidalgo : 
%G eng
%U https://hdl.handle.net/21.11116/0000-0007-2F43-A
%R 10.1016/j.humimm.2019.07.293
%F OTHER: shh2306
%7 2019-07-22
%D 2020
%* Review method: peer-reviewed
%X We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 122 Mexicans from the state of Hidalgo living in the city of Pachuca (N = 41) and rural communities (N = 81), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in Hidalgo include eight Native American and one European haplotypes. Admixture estimates revealed that the main genetic components in Hidalgo are Native American (58.93 ± 2.16 by ML; 54.51 of Native American haplotypes) and European (32.49 ± 2.88 by ML; 28.69 of European haplotypes), and a relatively high African genetic component (8.58 ± 0.93 by ML; 6.97 of African haplotypes).
%K HLA, Immunogenetics, Population genetics, Hidalgo, Admixture
%J Human Immunology
%V 81
%N 9
%& 535
%P 535 - 538
%I Elsevier
%C New York, N.Y.
%@ 0198-8859