%0 Thesis %A Feldman, Michal %+ Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society %T Tracing past human mobility and disease in western Eurasia by the genetic analysis of ancient human remains : %G eng %U https://hdl.handle.net/21.11116/0000-0007-3103-E %R 10.22032/dbt.41330 %F OTHER: shh2628 %I Friedrich-Schiller-Universität Jena, Fakultät für Biowissenschaften %C Jena %D 2020 %8 27.01.2020 %P 258 %V phd %9 phd %X The emerging field of Archaeogenetics has been claiming a pivotal role in ongoing efforts to reconstruct the human past. In this thesis, Archaeogenetic approaches are used to reconstruct genomic data from historical and archaeological human remains. These molecular fossils are than used to trace and characterize past human mobility and disease. The papers comprising this thesis are centered around three noteworthy events in human history over the last 15,000 years: the Neolithic transition in central Anatolia; the Bronze Age collapse in the southern Levant; and the Justinianic Plague. The demographic processes that have led to these events are investigated as well as their long term genetic impact. %K Life sciences; biology - 570 %K Archaeogenetics, ancient DNA, Neolithic transition, Anatolia, southern Levant, Philistines, Justinianic Plague, Bubonic Plague, Yersinia Pestis %Z 1. Introduction 1.1. Looking back by moving forward – a short history of Archaeogenetics 1.2. Human mobility in ancient west Eurasia 1.2.1. Pots versus peoples – testing historical questions using aDNA 1.2.2. Genetic perspectives on the Neolithic transition in the Near East 1.2.3. The eastern Mediterranean Bronze Age collapse and the origins of the Philistines 1.3. Archaeogenetic perspectives on the Justinianic Plague 1.3.1. Y. pestis and the historic Plague pandemics 1.3.2. An historical overview on the Justinianic Plague 1.3.3. The natural history of Y. pestis 2. Aim of the thesis 3. Overview of Manuscripts and author’s Contribution 4. Manuscript A 5. Manuscript B 6. Manuscript C 7. Discussion 7.1. The role of aDNA in recording history 7.2. Challenges in DNA retrieval and interpretation 8. References 9. Summary 10. Zusammenfassung