%0 Journal Article
%A Vernot, Benjamin
%A Zavala, Elena I.
%A Gómez-Olivencia, Asier
%A Jacobs, Zenobia
%A Slon, Viviane
%A Mafessoni, Fabrizio
%A Romagné, Frédéric
%A Pearson, Alice
%A Petr, Martin
%A Sala, Nohemi
%A Pablos, Adrián
%A Aranburu, Arantza
%A de Castro, José María Bermúdez
%A Carbonell, Eudald
%A Li, Bo
%A Krajcarz, Maciej T.
%A Krivoshapkin, Andrey I.
%A Kolobova, Kseniya A.
%A Kozlikin, Maxim B.
%A Shunkov, Michael V.
%A Derevianko, Anatoly P.
%A Viola, Bence
%A Grote, Steffi
%A Essel, Elena
%A López Herráez, David
%A Nagel, Sarah
%A Nickel, Birgit
%A Richter, Julia
%A Schmidt, Anna
%A Peter, Benjamin
%A Kelso, Janet
%A Roberts, Richard G.
%A Arsuaga, Juan-Luis
%A Meyer, Matthias
%+ Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Genomes, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
The Minerva Research Group for Bioinformatics, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
The Minerva Research Group for Bioinformatics, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Human Population History, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Genetic Diversity through Space and Time, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
The Minerva Research Group for Bioinformatics, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
%T Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments : 
%G eng
%U https://hdl.handle.net/21.11116/0000-0008-513C-A
%R 10.1126/science.abf1667
%D 2021
%8 15.04.2021
%* Review method: peer-reviewed
%X Bones and teeth are important sources of Pleistocene hominin DNA, but are rarely recovered at archaeological sites. Mitochondrial DNA has been retrieved from cave sediments, but provides limited value for studying population relationships. We therefore developed methods for the enrichment and analysis of nuclear DNA from sediments, and applied them to cave deposits in western Europe and southern Siberia dated to between approximately 200,000 and 50,000 years ago. We detect a population replacement in northern Spain approximately 100,000 years ago, accompanied by a turnover of mitochondrial DNA. We also identify two radiation events in Neanderthal history during the early part of the Late Pleistocene. Our work lays the ground for studying the population history of ancient hominins from trace amounts of nuclear DNA in sediments.
%J Science
%] eabf1667
%I American Association for the Advancement of Science
%@ 0036-8075