%0 Journal Article
%A Pfrengle, Saskia
%A Neukamm, Judith
%A Guellil, Meriam
%A Keller, Marcel
%A Molak, Martyna
%A Avanzi, Charlotte
%A Kushniarevich, Alena
%A Montes, Núria
%A Neumann, Gunnar U.
%A Reiter, Ella
%A Tukhbatova, Rezeda I.
%A Berezina, Nataliya Y.
%A Buzhilova, Alexandra P.
%A Korobov, Dmitry S.
%A Suppersberger Hamre, Stian
%A Matos, Vitor M. J.
%A Ferreira, Maria T.
%A González-Garrido, Laura
%A Wasterlain, Sofia N.
%A Lopes, Célia
%A Santos, Ana Luisa
%A Antunes-Ferreira, Nathalie
%A Duarte, Vitória
%A Silva, Ana Maria
%A Melo, Linda
%A Sarkic, Natasa
%A Saag, Lehti
%A Tambets, Kristiina
%A Busso, Philippe
%A Cole, Stewart T.
%A Avlasovich, Alexei
%A Roberts, Charlotte A.
%A Sheridan, Alison
%A Cessford, Craig
%A Robb, John
%A Krause, Johannes
%A Scheib, Christiana L.
%A Inskip, Sarah A.
%A Schuenemann, Verena J.
%+ Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society
MHAAM, Max Planck Institute for the Science of Human History, Max Planck Society
%T Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes : 
%G eng
%U https://hdl.handle.net/21.11116/0000-0009-5CFC-5
%R 10.1186/s12915-021-01120-2
%7 2021-10-05
%D 2021
%8 05.10.2021
%* Review method: peer-reviewed
%X Hansen’s disease (leprosy), widespread in medieval Europe, is today mainly prevalent in tropical and subtropical regions with around 200,000 new cases reported annually. Despite its long history and appearance in historical records, its origins and past dissemination patterns are still widely unknown. Applying ancient DNA approaches to its major causative agent, Mycobacterium leprae, can significantly improve our understanding of the disease’s complex history. Previous studies have identified a high genetic continuity of the pathogen over the last 1500 years and the existence of at least four M. leprae lineages in some parts of Europe since the Early Medieval period.
%J BMC Biology
%V 19
%] 220
%@ 1741-7007