%0 Journal Article %A Patrono, Livia V. %A Röthemeier, Caroline %A Kouadio, Leonce %A Couacy‐Hymann, Emmanuel %A Wittig, Roman M. %A Calvignac‐Spencer, Sébastien %A Leendertz, Fabian H. %+ Chimpanzees, Department of Primatology, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Behavior Ecology and Culture, Max Planck Institute for Evolutionary Anthropology, Max Planck Society %T Non‐invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capture : %G eng %U https://hdl.handle.net/21.11116/0000-000A-377B-F %R 10.1111/irv.12984 %7 2022-04-06 %D 2022 %* Review method: peer-reviewed %X Human respiratory pathogens have repeatedly caused lethal outbreaks in wild great

apes across Africa, leading to population declines. Nonetheless, our knowledge of

potential genomic changes associated with pathogen introduction and spread at the

human-great ape interface remains sparse. Here, we made use of target enrichment

coupled with next generation sequencing to non-invasively investigate five outbreaks

of human-introduced respiratory disease in wild chimpanzees living in Taï National

Park, Ivory Coast. By retrieving 34 complete viral genomes and three distinct

constellations of pneumococcal virulence factors, we provide genomic insights into

these spillover events and describe a framework for non-invasive genomic

surveillance in wildlife. %K non-invasive health monitoring, pathogen genomics, respiratory disease, wild great apes %J Influenza and Other Respiratory Viruses %V 16 %N 5 %& 858 %P 858 - 861 %] 12984 %I Wiley %@ 1750-26401750-2659