%0 Journal Article
%A Patrono, Livia V.
%A Röthemeier, Caroline
%A Kouadio, Leonce
%A Couacy‐Hymann, Emmanuel
%A Wittig, Roman M.
%A Calvignac‐Spencer, Sébastien
%A Leendertz, Fabian H.
%+ Chimpanzees, Department of Primatology, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Human Behavior Ecology and Culture, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
%T Non‐invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capture (advance online)  : 
%G eng
%U http://hdl.handle.net/21.11116/0000-000A-377B-F
%R 10.1111/irv.12984
%7 2022-04-06
%D 2022
%8 06.04.2022
%* Review method: peer-reviewed
%X Human respiratory pathogens have repeatedly caused lethal outbreaks in wild great
apes across Africa, leading to population declines. Nonetheless, our knowledge of
potential genomic changes associated with pathogen introduction and spread at the
human-great ape interface remains sparse. Here, we made use of target enrichment
coupled with next generation sequencing to non-invasively investigate five outbreaks
of human-introduced respiratory disease in wild chimpanzees living in Taï National
Park, Ivory Coast. By retrieving 34 complete viral genomes and three distinct
constellations of pneumococcal virulence factors, we provide genomic insights into
these spillover events and describe a framework for non-invasive genomic
surveillance in wildlife.
%K non-invasive health monitoring, pathogen genomics, respiratory disease, wild great apes
%J Influenza and Other Respiratory Viruses
%] 12984
%I Wiley
%@ 1750-26401750-2659