%0 Journal Article
%A Patrono, Livia V.
%A Röthemeier, Caroline
%A Kouadio, Leonce
%A Couacy‐Hymann, Emmanuel
%A Wittig, Roman M.
%A Calvignac‐Spencer, Sébastien
%A Leendertz, Fabian H.
%+ Chimpanzees, Department of Primatology, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
Department of Human Behavior Ecology and Culture, Max Planck Institute for Evolutionary Anthropology, Max Planck Society
%T Non‐invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capture  : 
%G eng
%U https://hdl.handle.net/21.11116/0000-000A-377B-F
%R 10.1111/irv.12984
%7 2022-04-06
%D 2022
%* Review method: peer-reviewed
%X Human respiratory pathogens have repeatedly caused lethal outbreaks in wild great
<br><br>apes across Africa, leading to population declines. Nonetheless, our knowledge of
<br><br>potential genomic changes associated with pathogen introduction and spread at the
<br><br>human-great ape interface remains sparse. Here, we made use of target enrichment
<br><br>coupled with next generation sequencing to non-invasively investigate five outbreaks
<br><br>of human-introduced respiratory disease in wild chimpanzees living in Taï National
<br><br>Park, Ivory Coast. By retrieving 34 complete viral genomes and three distinct
<br><br>constellations of pneumococcal virulence factors, we provide genomic insights into
<br><br>these spillover events and describe a framework for non-invasive genomic
<br><br>surveillance in wildlife.
%K non-invasive health monitoring, pathogen genomics, respiratory disease, wild great apes
%J Influenza and Other Respiratory Viruses
%V 16
%N 5
%& 858
%P 858 - 861
%] 12984
%I Wiley
%@ 1750-26401750-2659