%0 Journal Article %A Sümer, Arev P. * %A Rougier, Hélène %A Villalba-Mouco, Vanessa %A Huang, Yilei %A Iasi, Leonardo N.M. %A Essel, Elena %A Bossoms Mesa, Alba %A Furtwaengler, Anja %A Peyrégne, Stéphane %A de Filippo, Cesare %A Rohrlach, Adam B. %A Pierini, Federica %A Mafessoni, Fabrizio %A Fewlass, Helen %A Zavala, Elena I. %A Mylopotamitaki, Dorothea %A Bianco, Raffaela A. %A Schmidt, Anna %A Zorn, Julia %A Nickel, Birgit %A Patova, Anna %A Posth, Cosimo %A Smith, Geoff M. %A Ruebens, Karen %A Sinet-Mathiot, Virginie %A Stoessel, Alexander %A Dietl, Holger %A Orschiedt, Jörg %A Kelso, Janet %A Zeberg, Hugo %A Bos, Kirsten I. %A Welker, Frido %A Weiss, Marcel %A McPherron, Shannon %A Schüler, Tim %A Hublin, Jean-Jacques %A Velemínský, Petr %A Brůžek, Jaroslav %A Peter, Benjamin M. %A Meyer, Matthias %A Meller, Harald %A Ringbauer, Harald %A Hajdinjak, Mateja %A Prüfer, Kay * %A Krause, Johannes * %+ Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Origins, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society %T Earliest modern human genomes constrain timing of Neanderthal admixture (advance online) : %G eng %U https://hdl.handle.net/21.11116/0000-0010-5432-7 %R 10.1038/s41586-024-08420-x %7 2024-12-12 %D 2024 %8 12.12.2024 %* Review method: peer-reviewed %X Modern humans arrived in Europe more than 45,000 years ago, overlapping at least 5,000 years with Neanderthals1–4. Limited genomic data from these early modern humans have shown that at least two genetically distinct groups inhabited Europe, represented by Zlatý kůň, Czechia3 and Bacho Kiro, Bulgaria2. Here we deepen our understanding of early modern humans by analyzing one high-coverage genome and five low-coverage genomes from ~45,000 year-old remains from Ilsenhöhle in Ranis, Germany4, and a further high-coverage genome from Zlatý kůň. We show that distant familial relationships link the Ranis and Zlatý kůň individuals and that they were part of the same small, isolated population that represents the deepest known split from the Out-of-Africa lineage. Ranis genomes harbor Neanderthal segments that originate from a single admixture event shared with all non-Africans that we date to ~45,000-49,000 years ago. This implies that ancestors of all non-Africans sequenced to-date resided in a common population at this time, and further suggests that modern human remains older than 50,000 years from outside Africa represent different non-African populations. %K Archaeology, Genomics, Population genetics %J Nature %I Nature Publishing Group %C London %@ 0028-0836