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A “novel” developmental mechanism and its consequences on our views on brain evolution
July 01, 2016 14:00
Speaker: Alain Prochiantz, Collège de France, Paris, France
The Institute Seminar Series

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MPI-EVA, Deutscher Platz 6, Lecture hall, 2nd floor

- 14:00 Alain Prochiantz: A “novel” developmental mechanism and its consequences on our views on brain evolution

- 15:30 Discussion and soft drinks just outside the lecture hall

Abstract: Minor modifications during development can have important effects on the overall brain structure and physiology. Thus mutations in “developmental genes” or in their regulatory elements are of interest to understand how the brain has evolved, the human brain in particular. Our laboratory has discovered a novel property of homeoprotein transcription factors, namely their ability to be transported between cells and to behave not only as cell autonomous developmental regulators but also as non-cell autonomous morphogens. We shall expose and discuss how this non-cell autonomous activity is involved in progenitor division/migration/differentiation, the formation of boundaries at early stages of brain development, axon guidance and the biological activity of inhibitory interneurons in the cerebral cortex.

Some information on the speaker and a list of his publications can be found at http://www.college-de-france.fr/site/en-alain-prochiantz/index.htm

The series featuring internal and external speakers takes place roughly every 1-2 months on Friday early afternoons. The committee organizing the seminar series consists of: Aida Andrés, Catherine Crockford, Jan Engelmann, Alexander Stoessel, Sandra Jacob and Jörg Noack. Please contact any of them with comments or suggestions.

Sandra Jacob, -122 or -156

E-mail: jacob[>>> Please replace the brackets with an AT sign! <<<]eva.mpg.de