Program
Wednesday, 25th February 2015
Time | Description |
---|---|
15:00 | Registration opens |
17:30 | Welcome remarks |
17:40 | Michael Lynch: Evolution of the mutation rate |
18:10 | Jean-Jacques Hublin: Timing Human Evolution |
18:40 | Reception |
20:30 | Pub crawl (Optional – Please sign up on-site) |
Thursday, 26th February 2015
Time | Description |
---|---|
9:00 | Discussion |
9:30 | Agnar Helgason: The Y chromosome point mutation rate in humans |
10:00 | Mikkel Schierup: Somatic and germline de novo SNVs and short indels in high coverage Danish trios |
10:30 | Break |
10:50 | David Reich: Genetic evidence for complex speciation of humans and chimpanzees: Has the evidence stood up? |
11:20 | Guy Amster: A sex and age-dependent neutral model for X and autosomes explains polymorphism and divergence patterns in great apes |
11:40 | Mark Stoneking: An overview of mutation rate estimates for human mtDNA |
12:00 | Kateryna Makova: Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA |
12:30 | Lunch |
13:30 | Michael Stratton: Signatures of mutational processes |
14:00 | Sebastian Zöllner: Genomewide patterns of human germline mutation and signatures of mutational processes |
14:20 | Raheleh Rahbari: Timing, rates and spectra of human germline mutation |
14:40 | Kelley Harris: Recent evolution of the mutation rate and spectrum in Europeans |
15:10 | Poster Session I |
15:40 | Priya Moorjani: The generation time effect on mutation rates in primates |
16:00 | Sarah Lindsay: Modelling the effects of age and mutagen exposure in the mammalian genome |
16:20 | Molly Przeworski: Evaluating the impact of changing generation times on mutation rates |
16:50 | Anne Goriely: The selfish effect of paternal age on mutation rate |
17:10 | Poster Session II |
17:40 | Aylwyn Scally: Evidence for the hominoid slowdown and its potential causes |
18:10 | David Begun: Molecular divergence estimates and the Miocene fossil record |
18:30 | Qiaomei Fu: Calibrating the human mutation rate using an ancient genome |
18:50 | Ilan Gronau: Improving the dates of ancient DNA samples using population-level sequence comparisons |
19:10 | Sessions End |
19:30 | Transport to Restaurant Thüringer Hof by Bus |
20:00 | Dinner at Thüringer Hof |
Friday, 27th February 2015
Time | Description |
---|---|
9:00 | Richard Durbin: Estimation of the ratio of mutation to recombination rate from four population sequences |
9:30 | Pier Francesco Palamara: Inference of human mutation rates using cryptic relatedness in a European population |
9:50 | Mark Lipson: Calibrating the human mutation rate via ancestral recombination density in diploid genomes |
10:10 | Poster Session I + II |
11:00 | Shamil Sunyaev: Genome-wide patterns and properties of de novo mutations in humans |
11:30 | Tobias Warnecke: Germline epigenetics and evolution at hydroxymethylated cytosines |
11:50 | Vladimir Seplyarskiy: Polymerase ζ activity is linked to replication timing in humans: evidence from mutational signatures |
12:10 | Irene Tiemann-Boege: Mutagenesis at recombination hotspots |
12:30 | Lunch |
13:30 | Discussion and closing remarks |
15:00 | End |
Poster Sessions
Poster Number | Poster Session | Title |
---|---|---|
1 | I | Arslan et al.: Paternal age effects on offspring mortality and fertility as indicators of the strength of purifying selection in ancient Québec and Krummhörn populations |
2 | II | Cartwright et al.: DeNovoGear: New methods for estimate mutation rates using related individuals and cells |
3 | I | Posth et al.: Interdisciplinary investigation of an archaic hominin femur from the Swabian Jura (South-West Germany) |
4 | II | Mathieson et al. Calibrating demographic models with ancient DNA |
5 | I | Barbieri et al.: Estimating the TMRCA of the Y chromosome phylogeny with new sequence data from southern Africa |
6 | II | De Maio et al.: Estimating mutation rates and selection coefficients from great ape genomes using polymorphism-aware phylogenetic models |
7 | I | Kloosterman et al.: Origin, frequency and functional impact of de novo structural changes in the human genome |
8 | II | Skoglund et al.: Mutation rate-based dating of ancient genomes |
9 | I | Lipatov et al.: Detection of missing variants in 2nd generation DNA sequencing data |
10 | II | Jalilian et al.: Analysis of functional variation in 11 cytochrome P450 (CYP) genes: mutation rate is dependent among CYP genes |
11 | I | Schiffels et al.: Inferring population sizes and separation times from a large number of samples using rare variants |
12 | II | Xue et al.: Constraints on the human Y-chromosomal base substitution mutation rate from ancient DNA sequences |
13 | I | Saag et al.: Y-chromosomal mutation rate estimate from ancient DNA sequences |
14 | II | Gao et al.: A model for how somatic mutations accrue over time |