We develop methods for the retrieval of DNA sequences from archaeological and paleontological remains. In particular, we continuously try to improve the amount and quality of DNA sequences retrieved from ancient specimens.
We apply these techniques to elucidate the history of hominins. For example, we have sequenced the Neandertal genome to high quality. We have also described a hominin group related to Neandertals in Asia, Denisovans, and sequenced a Denisovan genome to high coverage. In addition, we are attempting to retrieve DNA also from older hominin remains.
Website of the Neandertal Genome project
TEDGlobal Talk by Svante Pääbo
New York Times Video: "The Neanderthal Inside Us"
NatGeo TV Sverige (on Youtube): Breakthrough Prize - Svante Pääbo