Contemporary Europeans have as many as three times more Neanderthal variants in genes involved in lipid catabolism than Asians and Africans

Although Neanderthals are extinct, fragments of their genomes persist in modern humans. These shared regions are unevenly distributed across the genome and some regions are particularly enriched with Neanderthal variants. An international team of researchers led by Philipp Khaitovich of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, and the CAS-MPG Partner Institute for Computational Biology in Shanghai, China, show that DNA sequences shared between modern humans and Neanderthals are specifically enriched in genes involved in the metabolic breakdown of lipids. This sharing of genes is seen mainly in contemporary humans of European descent and may have given a selective advantage to the individuals with the Neanderthal variants.