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Divyaratan Popli

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Abteilung für Evolutionäre Genetik
Max-Planck-Institut für evolutionäre Anthropologie
Deutscher Platz 6
04103 Leipzig

Telefon: +49 (0) 341 3550 525
E-Mail: divyaratan_popli@[>>> Please remove the text! <<<]eva.mpg.de

Research Interests

I am interested in developing statistical models and bioinformatic tools to answer questions about the relationships of our ancestors using ancient DNA. In the last few decades, extensive genomic data have been collected from thousands of archaeological remains, and the pool of ancient organic materials suitable for genome sequencing is continuously expanding. Familial relatedness of ancient individuals can provide insights into their culture and social hierarchy, and is relevant for downstream genetic analyses. Similarly, genetic relatedness between populations is informative about structure and past admixtures. However, estimating relatedness on either family or population level from ancient DNA is difficult due to low-coverage, ascertainment bias, or contamination from various sources. My PhD thesis under the supervision of Peter F. Stadler and Benjamin M. Peter therefore focuses on developing new methods to study relatedness taking these issues into account.

Curriculum Vitae

Current Position

10/2018 -PresentPhD student at the Department of Evolutionary Genetics,
Max Planck Institute for Evolutionary Anthropology, Leipzig
Title: ”Estimating relatedness with ancient DNA”.
Supervisors: Peter Stadler, Benjamin M. Peter

    
Education

07/2014 - 02/2017 Master of Science in Biological Sciences,
Specialization in Molecular Biophysics
Indian Institute of Science, Bangalore
Title: “Effect of Ultrasound on Neuronal Network Communication”  
Supervisor:  Sujit K. Sikdar, Bharadwaj Amrutur
07/2010 - 05/2014  Bachelor of Technology in Biological Sciences and Bioengineering
Indian Institute of Technology, Kanpur

   
Additional Research Experience

05/2013 - 07/2013Research project in Cognitive Neuroscience Center,
University of Amsterdam
Title: “Relationship between Task-Unrelated Thoughts and pupil diameter”.
Supervisor: Birte Forstmann
12/2012 - 01/2013Research project in National Brain Research Center, India
Title: “In silico analysis of miRNA-target interaction”.
Supervisor: Sourav Banerjee

Publications

Popli, D. (2024). Estimating relatedness with ancient DNA. PhD Thesis, Universität, leipzig.
Open Access    BibTeX   Endnote   

Gnecchi Ruscone, G. A., Rácz, Z., Samu, L., Szeniczey, T., Faragó, N., Knipper, C., Friedrich, R., Zlámalová, D., Traverso, L., Liccardo, S., Wabnitz, S., Popli, D. R., Wang, K., Radzeviciute, R., Gulyás, B., Koncz, I., Balogh, C., Lezsák, G. M., Mácsai, V., Bunbury, M. M. E., Spekker, O., le Roux, P., Szécsényi-Nagy, A., Mende, B. G., Colleran, H., Hajdu, T., Geary, P., Pohl, W., Vida, T., Krause, J., & Hofmanová, Z. (2024). Network of large pedigrees reveals social practices of Avar communities. Nature, 629(8011), 376-383.
Open Access    DOI    BibTeX   Endnote   

Popli, D., Peyrégne, S., & Peter, B. M. (2023). KIN: a method to infer relatedness from low-coverage ancient DNA. Genome Biology, 24: 10.
Open Access    DOI    BibTeX   Endnote   

Popli, D., Peyrégne, S., & Peter, B. M. (2023). Estimating genetic relatedness from ancient DNA. In H. Meller, J. Krause, W. Haak, & R. Risch (Eds.), Kinship, sex, and biological relatedness: the contribution of archaeogenetics to the understanding of social and biological relations: 15. Mitteldeutscher Archäologentag vom 6. bis 8. Oktober 2022 in Halle (Saale) (pp. 95-99). Halle (Saale): Landesamt für Denkmalpflege und Archäologie Sachsen-Anhalt - Landesmuseum für Vorgeschichte.
Open Access    DOI    BibTeX   Endnote   

Skov, L., Peyrégne, S., Popli, D. R., Iasi, L. N., Devièse, T., Slon, V., Zavala, E. I., Hajdinjak, M., Sümer, A., Grote, S., Bossoms Mesa, A., López Herráez, D., Nickel, B., Nagel, S., Richter, J., Essel, E., Gansauge, M.-T., Schmidt, A., Korlevic, P., Comeskey, D., Derevianko, A. P., Kharevich, A., Markin, S. V., Talamo, S., Douka, K., Krajcarz, M. T., Roberts, R. G., Higham, T., Viola, B., Krivoshapkin, A. I., Kolobova, K. A., Kelso, J., Meyer, M., Pääbo, S., & Peter, B. M. (2022). Genetic insights into the social organization of Neanderthals. Nature, 610, 519-525.
Open Access    DOI    BibTeX   Endnote