Svante Pääbo
Director
Max Planck Institute for Evolutionary Anthropology
Deutscher Platz 6
04103 Leipzig
tel: +49 341 3550 500
e-mail: paabo@[>>> Please remove the text! <<<]eva.mpg.de
Office: Level 3, Room U3.93
1955 | Born in Stockholm, Sweden. |
1975-1976 | School of Interpreters, Swedish Defense Forces. |
1975-1981 | Studies at the Faculty of Humanities, University of Uppsala, including History of Science, Egyptology, Russian. |
1977-1980 | Medical studies at the University of Uppsala, Sweden. |
1979-1980 | Part time research and teaching at the Department of Cell Biology, Uppsala, and Roche Institute for Molecular Biology, Nutley, N.J. USA. |
1981-1986 | Full time research as PhD-student at the Department of Cell Research, Uppsala. |
1986 | PhD degree at University of Uppsala, Sweden. |
1986-1987 | Postdoctoral research at the Institute for Molecular Biology II, University of Zürich, Switzerland. |
1987 | Short period of work at Imperial Cancer Research Fund, London, UK. |
1987-1990 | Postdoctoral research at Department of Biochemistry, University of California at Berkeley, USA. |
1990 | Docent (habilitation) in Medical Genetics, University of Uppsala, Sweden. |
1990-1998 | Full Professor (C4) of General Biology, University of Munich, Germany. |
1997- | Director, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. |
1999- | Professor of Genetics and Evolutionary Biology, University of Leipzig, Germany. |
2003-2015 | Guest Professor of Comparative Genomics, University of Uppsala, Sweden. |
2016- | Honorary Research Fellow, Natural History Museum, London, UK. |
2020- | Adjunct Professor, Okinawa Institute of Science and Technology, Japan. |
Scholarships, Fellowships and Honors
1984-1986 | Training scholarship from the Swedish Cancer Society. |
1986 | EMBO short-term fellowship. |
1987 | FEBS fellowship. |
1987-1989 | EMBO long-term fellowship. |
1992 | Leibniz Prize of the German Science Foundation. |
1994 | Honorary Doctorate, University of Zurich, Switzerland. |
1996 | EMBL Distinguished Visitor Lecture, Heidelberg, Germany. |
1998 | Member, Academia Europaea. Max Delbrück Medal, Berlin, Germany. |
1999 | Member, Berlin-Brandenburgische Akademie der Wissenschaften, Berlin, Germany. Carus Medal and Prize, Halle and Schweinfurt,Germany. Member, EMBO. |
2000 | Honorary Doctorate, University of Helsinki, Finland. Rudbeck Prize, Uppsala, Sweden. Member, Royal Academy of Sciences, Stockholm, Sweden. |
2002 | Member, Deutsche Akademie der Naturforscher Leopoldina, Halle, Germany. Foreign Member, Finnish Society of Sciences and Letters, Helsinki, Finland. |
2003 | Leipzig Science Prize, Leipzig, Germany. Ernst Schering Prize, Berlin, Germany. Member, Saxonian Academy of Sciences, Leipzig, Germany. |
2004 | Foreign Member, National Academy of Sciences, Washington DC, USA. |
2005 | Louis Jeantet Prize for Medicine, Geneva, Switzerland. Virchow Medal, University of Würzburg, Germany. |
2007 | Time Magazine 100 Most Influential People in the World. Emeritus Member, Academie Internationale de Philosophie des Sciences, Brussels, Belgium. |
2008 | Order of Terra Mariana, 3rd Class, Republic of Estonia. Gorjanovic-Kramberger Medal, Zagreb, Croatia. Honorary Professor, Graduate University of the Chinese Academy of Sciences, Beijing, China. Academy of Achievement Honoree, Washington D.C., USA. Pour le mérite, Bonn, Germany. Honorary Doctorate, Royal Institute of Technology, Stockholm, Sweden. |
2009 | Kistler Prize, Seattle, WA, USA. Grosses Bundesverdienstkreuz mit Stern, Berlin, Germany. Darwin-Plakette, Deutsche Akademie der Naturforscher Leopoldina, Halle, Germany. Anatomische Les, Amsterdam, Holland. |
2010 | Theodor Bücher Medal, Federation of European Biochemical Societies. Honorary Member, Croatian Anthropological Society, Zagreb, Croatia. |
2011 | Newcomb-Cleveland Prize, AAAS, Washington, D.C. Foreign Member, American Academy of Arts and Sciences, Cambridge MA, USA. Biochemical Analysis Prize, DGKL, Berlin, Germany. |
2012 | H.M. The King's Medal (Kon:sGM12mhb), Stockholm, Sweden. Honorary Doctor of Medicine, Karolinska Institute, Stockholm, Sweden. Corresponding Member, Croatian Academy of Sciences and Arts, Zagreb, Croatia. Heisse Kartoffel, Leipzig, Germany. |
2013 | Gruber Genetics Prize, New Haven, CT, USA. Foreign Member, Royal Academy of Engineering, Stockholm, Sweden. |
2014 | Learning Ladder Prize, Stockholm, Sweden. Allen Distinguished Investigator. |
2015 | Lomonosov Large Gold Medal, Russian Academy of Sciences, Moscow. Doctor of Science h.c., National University of Ireland, Galway. Breakthrough Prize in Life Sciences, Mountain View, CA, USA. Honorary Doctor, Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Novosibirsk. |
2016 | Foreign Associate, Académie des Sciences, Institut de France. Foreign Member, Royal Society of London, UK. Keio Medical Science Prize, Keio University, Japan. |
2017 | Honorary Member, New York Academy of Sciences, USA. Dan David Prize, Tel Aviv University, Israel. Nomis Distinguished Scientist Award, Zurich, Switzerland. |
2018 | Nakasone Award, Human Frontier Science Program, Strasbourg, France. Princess of Asturias Award for Technical and Scientific Research, Oviedo, Spain. Körber European Science Prize, Hamburg, Germany. Nierenberg Prize, Scripps Institution of Oceanography, La Jolla, California. |
2019 | The Wiley Prize in Biomedical Sciences, New York, USA. Honorary Doctorate, Okinawa Institute of Science and Technology, Japan. Darwin-Wallace Medal, The Linnean Society of London, UK. Foreign member, Estonian Academy of Sciences, Tallinn. |
2020 | The Japan Prize, Tokyo. Honorary Doctor of Science, Yale University, USA. |
2021 | Foreign Member, Accademia Nazionale dei Lincei, Rome, Italy. The Massry Prize, Beverly Hills, CA, USA. Prix International Fyssen, Paris, France. |
2022 | The Nobel Prize in Physiology or Medicine, Stockholm, Sweden. |
2023 | Ehrenmedaille der Stadt Leipzig, Germany. Doctor of Science honoris causa, American Museum of Natural History, New York, USA. Foreign Member of the Chinese Academy of Sciences, Beijing. Alumnus of the Year, Uppsala University, Sweden. |
2024 | Doctor Honoris Causa, University of Oviedo, Asturias, Spain. Royal Order of the Polar Star (KmstkNO), Stockholm, Sweden. |
Scientific service
1990-1993 | Associate Editor, Journal of Human Evolution. |
1991-2004 | Editorial Board, Genome Research. |
1991- | Editorial Board, Molecular Phylogenetics and Evolution. |
1991-1995 | HUGO Committee for Human Genetic Diversity. |
1992-1993 | Life Sciences Group, European Community Program "Human Capital and Mobiliy". |
1993-1996 | Panel member, Ancient Biomolecules Initiative, Science & Engineering Research Council, UK. |
1995-2002 | Editorial Board, Biological Chemistry. |
1996-2006 | Editorial Board, BioTechniques. |
1996-2001 | Advisor, Gene. |
1996 | EMBL Review Board, Biological Instrumentation Programme. |
1997-2002 | Editorial Board, Human Heredity. |
1997-2000 | Editorial Board, Ancient Biomolecules. |
1997 | Main organizer, Annual Meeting of the Society for Molecular Biology and Evolution, Garmisch-Partenkirchen, Germany. |
1997-2005 | Board of Directors, "Genome Research" and "Cell Factory for functional Genomics" programs. Foundation for Strategic Research, Sweden. |
1998 | Organizer, Cold Spring Harbor Meeting on Human Evolution. |
2000 | Organizer, Banbury Meeting, Cold Spring Harbor Laboratory. |
2000-2003 | Scientific Advisory Board, Pyrosequencing AB, Sweden. |
2001 | Organizer, SNP Meeting, Stockholm, Sweden. |
2001-2005 | Kuratorium, Leipziger Stiftung für Innovation und Technologietransfer. |
2004-2006 | Organizer, Cold Spring Harbor Meeting “The Biology of Genomes”. |
2004-2006 | Scientific Advisory Board, Joint Genome Institute, Department of Energy, Walnut Creak, California, USA. |
2005-2007 | Chair, Scientific Advisory Board, Uppsala Centre for Comparative Genomics, Sweden. |
2005 | Organizer, "International Workshop on Encoding Information in DNA Sequences", Okinawa, Japan. |
2007 | Organizer, "Symposium on the Evolution of Brain, Behaviour & Intelligence", Hinxton, UK. Organizer, "Linnaeus Classification of Humans Revisited", Uppsala, Sweden. |
2008- | Scientific Advisory Board, Cold Spring Harbor Asia, Suzhou, China. |
2014- | Scientific Advisory Board, SciLifeLab, Sweden. |
2016-2020 | Editorial Board, Cell. |
2024 | NOMIS Foundation Honorary Council, Zurich, Switzerland. |
Teaching
1979-1980 | Teaching assistant, Medical Cell Biology and Histology. |
1981-1986 | Lectures in Cell Biology and Genetics for medical students. |
1980-1986 | Lectures in History of Science for Egyptology students. |
1987 | Course in pedagogy for faculty, University of Uppsala. |
1991-1998 | Organization of theoretical and practical teaching in general biology and evolution, University of Munich. |
1999- | Teaching in molecular evolutionary biology, University of Leipzig. |
Publications
Artikel
1 | Jones, B. N., Lewis, R. V., & Pääbo, S. (1980). Effects of flow rate and eluant composition on the high performance liquid chromatography of proteins. Journal of Liquid Chromatography, 3(9), 1373-1383. |
2 | Jones, B. N., Pääbo, S., & Stein, S. (1981). Amino acid analysis and enzymatic sequence determination of peptides by an improved o-phthaldialdehyde precolumn labeling procedure. Journal of Liquid Chromatography, 4(4), 565-586. |
3 | Pääbo, S., Lundqvist, G., Peterson, B., & Andersson, A. (1981). Hormone content of pancreatic islets subjected to different in vitro and in vivo functional demands. Experentia, 37, 1213-1214. |
4 | Kämpe, O., Bellgrau, D., Hammerling, U., Lind, P., Pääbo, S., Severinsson, L., & Peterson, P. (1983). Complex formation of class I transplantation antigens and a viral glycoprotein. The Journal of Biological Chemistry, 258(17), 10594-10598. |
5 | Pääbo, S., Weber, F., Kämpe, O., Schaffner, W., & Peterson, P. (1983). Association between transplantation antigens and a viral membrane protein synthesized from a mammalian expression vector. Cell, 33(2), 445-453. |
6 | Pääbo, S., Kämpe, O., Severinsson, L., Andersson, M., Fernandez, C., & Peterson, P. (1985). The association between class-I transplantation antigens and an adenovirus membrane protein. Progress in Allergy, 36, 114-134. |
7 | Pääbo, S. (1984). Über den Nachweis von DNA in altägyptischen Mumien. Das Altertum, 30, 213-218. |
8 | Pääbo, S. (1985). Preservation of DNA in ancient Egyptian mummies. Journal of Archaeological Science, 12(6), 411-417. |
9 | Pääbo, S. (1985). Molecular cloning of ancient Egyptian mummy DNA. Nature, 314, 644-645. |
10 | Andersson, M., Pääbo, S., Nilsson, T., & Peterson, P. A. (1985). Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance. Cell, 43(1), 215-222. |
11 | Pääbo, S., Weber, F., Nilsson, T., Schaffner, W., & Peterson, P. (1986). Structural and functional dissection of an MHC class I antigen-binding adenovirus glycoprotein. EMBO Journal, 5(8), 1921-1927. |
12 | Pääbo, S., Nilsson, T., & Peterson, P. (1986). Adenoviruses of subgenera B, C, D, and E modulate cell-surface expression of major histocompatibility complex class I antigens. Proceedings of the National Academy of Sciences of the United States of America, 83(24), 9665-9669. |
13 | Pääbo, S. (1986). Molecular genetic investigations of ancient human remains. Cold Spring Harbor Symposia on Quantitative Biology, 51, 441-446. |
14 | Pääbo, S. (1987). Molecular genetic methods in archaeology - a prospect. Anthropologischer Anzeiger, 45(1), 9-17. |
15 | Andersson, L., Pääbo, S., & Rask, L. (1987). Is allograft rejection a clue to the mechanism promoting MHC polymorphism? Immunology Today, 8(7-8), 206-209. |
16 | Pääbo, S., Bhat, B. M., Wold, W. S., & Peterson, P. A. (1987). A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum. Cell, 50(2), 311-317. |
17 | Pääbo, S., & Wilson, A. C. (1988). Polymerase chain reaction reveals cloning artefacts. Nature, 334, 387-388. |
18 | Pääbo, S., Gifford, J. A., & Wilson, A. C. (1988). Mitochondrial DNA sequences from a 7000-year old brain. Nucleic Acids Research, 16(20), 9775-9787. |
19 | Pääbo, S., Severinsson, L., Andersson, M., Martens, I., Peterson, P. A., & Nilsson, T. (1989). Adenovirus proteins and MHC expression. Advances in Cancer Research, 52, 151-163. |
20 | Ljunggren, H., Pääbo, S., Cochet, M., Kling, G., Kourilsky, P., & Kärre, K. (1989). Molecular analysis of H-2-deficient lymphoma lines. Distinct defects in biosynthesis and association of MHC class I heavy chains and beta 2-microglobulin observed in cells with increased sensitivity to NK cell lysis. Journal of Immunology, 142(8), 2911-2917. |
21 | Pääbo, S. (1989). Ancient DNA: Extraction, characterization, molecular cloning, and enzymatic amplification. Proceedings of the National Academy of Sciences of the United States of America, 86(6), 1939-1943. |
22 | Kocher, T., Thomas, W., Meyer, A., Edwards, S., Pääbo, S., Villablanca, F., & Wilson, A. (1989). Dynamics of mitochondrial DNA evolution in animals: Amplification and sequencing with conserved primers. Proceedings of the National Academy of Sciences of the United States of America, 86(16), 6196-6200. |
23 | Pääbo, S., Higuchi, R. G., & Wilson, A. C. (1989). Ancient DNA and the polymerase chain reaction: The emerging field of molecular archaeology (Minireview). The Journal of Biological Chemistry, 264(17), 9709-9712. |
24 | Thomas, R. H., Schaffner, W., Wilson, A. C., & Pääbo, S. (1989). DNA phylogeny of the extinct marsupial wolf. Nature, 340, 465-467. |
25 | Pääbo, S., Irwin, D., & Wilson, A. (1990). DNA damage promotes jumping between templates during enzymatic amplification. The Journal of Biological Chemistry, 265(8), 4718-4721. |
26 | Thomas, W. K., Pääbo, S., Villablanca, F. X., & Wilson, A. C. (1990). Spatial and temporal continuity of kangaroo rat populations shown by sequencing mitochondrial DNA from museum specimens. Journal of Molecular Evolution, 31(2), 101-112. |
27 | Thomas, R. H., Pääbo, S., & Wilson, A. C. (1990). Chance marsupial relationships (Reply). Nature, 345, 394. |
28 | Pääbo, S., Thomas, W. K., Whitfield, K. M., Kumazawa, Y., & Wilson, A. C. (1991). Rearrangements of mitochondrial transfer RNA genes in marsupials. Journal of Molecular Evolution, 33(5), 426-430. |
29 | Ward, R., Frazier, B., Dew-Jager, K., & Pääbo, S. (1991). Extensive mitochondrial diversity within a single Amerindian tribe. Proceedings of the National Academy of Sciences of the United States of America, 88(19), 8720-8724. |
30 | Pääbo, S., & Wilson, A. C. (1991). Miocene DNA sequences - a dream come true? Current Biology, 1(1), 45-46. |
31 | Welsh, N., Pääbo, S., & Welsh, M. (1991). Decreased mitochondrial gene expression in isolated islets of rats injected neonatally with streptozotocin. Diabetologia, 34(9), 626-631. |
32 | Sidow, A., Wilson, A. C., & Pääbo, S. (1991). Bacterial DNA in Clarkia fossils. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 333, 429-433. |
33 | Pääbo, S. (1991). Amplifying DNA from archeological remains: A meeting report. PCR Methods and Applications, 1, 107-110. |
34 | Cooper, A., Mourer-Chauviré, C., Chambers, G., von Haeseler, A., Wilson, A., & Pääbo, S. (1992). Independent origins of New Zealand moas and kiwis. Proceedings of the National Academy of Sciences of the United States of America, 89(18), 8741-8744. |
35 | Pääbo, S., Wayne, R., & Thomas, R. (1992). On the use of museum collections for molecular genetic studies. Ancient DNA Newsletter, 1, 4-5. |
36 | Höss, M., Kohn, M., Pääbo, S., Knauer, F., & Schröder, W. (1992). Excrement analysis by PCR. Nature, 359, 199. |
37 | Goloubinoff, P., Pääbo, S., & Wilson, A. (1993). Evolution of maize inferred from sequence diversity of an Adh2 gene segment from archaeological specimens. Proceedings of the National Academy of Sciences of the United States of America, 90(5), 1997-2001. |
38 | Ward, R., Redd, A., Valencia, D., Frazier, B., & Pääbo, S. (1993). Genetic and linguistic differentiation in the Americas. Proceedings of the National Academy of Sciences of the United States of America, 90(22), 10663-10667. |
39 | Janke, A., & Pääbo, S. (1993). Editing of a tRNA anticodon in marsupial mitochondria changes its codon recognition. Nucleic Acids Research, 21(7), 1523-1525. |
40 | Schliewen, U., Fricke, H., Schartl, M., Epplen, J., & Pääbo, S. (1993). Which home for coelacanth? Nature, 363, 405. |
41 | Höss, M., & Pääbo, S. (1993). DNA extraction from Pleistocene bones by a silica-based purification method. Nucleic Acids Research, 21(16), 3913-3914. |
42 | von Haeseler, A., Janke, A., & Pääbo, S. (1993). Molecular phylogenetics. Verhandlungen der Deutschen Zoologischen Gesellschaft = Proceedings of the German Zoological Society, 86(2), 119-129. |
43 | Pääbo, S. (1993). Ancient DNA. Scientific American, 269(5), 86-92. |
44 | Thomas, W. K., & Pääbo, S. (1993). DNA sequences from old tissue remains. Mehods in Enzymology, 224, 406-419. |
45 | Schliewen, U. K., Tautz, D., & Pääbo, S. (1994). Sympatric speciation suggested by monophyly of crater lake cichlids. Nature, 368(6472), 629-632. |
46 | Janke, A., Feldmaier-Fuchs, G., Thomas, W. K., von Haeseler, A., & Pääbo, S. (1994). The marsupial mitochondrial genome and the evolution of placental mammals. Genetics, 137(1), 243-256. |
47 | Handt, O., Richards, M., Trommsdorff, M., Kilger, C., Simanainen, J., Georgiev, O., Bauer, K., Stone, A., Hedges, R., Schaffner, W., Utermann, G., Sykes, B., & Pääbo, S. (1994). Molecular genetic analyses of the Tyrolean Ice Man. Science, 264(5166), 1775-1778. |
48 | Höss, M., Pääbo, S., & Vereshchagin, N. (1994). Mammoth DNA sequences. Nature, 370(6488), 333. |
49 | Handt, O., Höss, M., Krings, M., & Pääbo, S. (1994). Ancient DNA: Methodological challenges. Experientia, 50(6), 524-529. |
50 | Bada, J. L., Wang, X. S., Poinar, H. N., Pääbo, S., & Poinar, G. O. (1994). Amino acid racemization in amber-entombed insects: Implications for DNA preservation. Geochimica et Cosmochimica Acta, 58(14), 3131-3135. |
51 | Gemmell, N. J., Janke, A., Western, P. S., Watson, J. M., Pääbo, S., & Graves, J. A. M. (1994). Cloning and characterization of the platypus mitochondrial genome. Journal of Molecular Evolution, 39(2), 200-205. |
52 | Cao, Y., Adachi, J., Janke, A., Pääbo, S., & Hasegawa, M. (1994). Phylogenetic relationships among eutherian orders estimated from inferred sequences of mitochondrial proteins: Instability of a tree based on a single gene. Journal of Molecular Evolution, 39(5), 519-527. |
53 | Pult, I., Sajantila, A., Simanainen, J., Georgiev, O., Schaffner, W., & Pääbo, S. (1994). Mitochondrial DNA sequences from Switzerland reveal striking homogeneity of European populations. Biological chemistry Hoppe-Seyler, 375, 837-840. |
54 | Kohn, M., Knauer, F., Stoffella, A., Schröder, W., & Pääbo, S. (1995). Conservation genetics of the European brown bear - a study using excremental PCR of nuclear and mitochondrial sequences. Molecular Ecology, 4(1), 95-103. |
55 | Dörner, M., & Pääbo, S. (1995). Nucleotide sequence of a marsupial LINE-1 element and the evolution of placental mammals. Molecular Biology and Evolution, 12(5), 944-948. |
56 | Mörl, M., Dörner, M., & Pääbo, S. (1995). C to U editing and modifications during the maturation of the mitochondrial tRNAAsp in marsupials. Nucleic Acids Research, 23(17), 3380-3384. |
57 | Yokobori, S.-I., & Pääbo, S. (1995). Transfer RNA editing in land snail mitochondria. Proceedings of the National Academy of Sciences of the United States of America, 92(22), 100432-10435. |
58 | Comas, D., Pääbo, S., & Bertranpetit, J. (1995). Heteroplasmy in the control region of human mitochondrial DNA. Genome Research, 5(1), 89-90. |
59 | Zischler, H., Hoss, M., Handt, O., von Haeseler, A., van der Kuyl, A., Goudsmit, J., & Pääbo, S. (1995). Detecting dinosaur DNA. Science, 268(5214), 1192-1193. |
60 | Pääbo, S. (1995). The Y chromosome and the origin of all of us (men). Science, 268(5214), 1141-1142. |
61 | Sajantila, A., Lahermo, P., Anttinen, T., Lukka, M., Sistonen, P., Savontaus, M., Aula, P., Beckman, L., Tranebjaerg, L., Gedde-Dahl, T., Issel-Tarver, L., DiRienzo, A., & Pääbo, S. (1995). Genes and languages in Europe: An analysis of mitochondrial lineages. Genome Research, 5(1), 42-52. |
62 | Yokobori, S.-I., & Pääbo, S. (1995). tRNA editing in metazoans. Nature, 377(6549), 490. |
63 | Zischler, H., Geisert, H., von Haeseler, A., & Pääbo, S. (1995). A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans. Nature, 378(6556), 489-492. |
64 | Sajantila, A., & Pääbo, S. (1995). Language replacement in Scandinavia. Nature Genetics, 11, 359-360. |
65 | Petri, B., Neuweiler, G., & Pääbo, S. (1995). Mitochondrial diversity and heteroplasmy in two European populations of the large mouse-eared bat, Myotis myotis. Symposia of the Zoological Society of London, 67, 397-403. |
66 | Janke, A., Gemmell, N. J., Feldmaier-Fuchs, G., von Haeseler, A., & Pääbo, S. (1996). The mitochondrial genome of a monotreme - the platypus (Ornithrohynchus anatinus). Journal of Molecular Evolution, 42(2), 153-159. |
67 | Höss, M., Dilling, A., Currant, A., & Pääbo, S. (1996). Molecular phylogeny of the extinct ground sloth Mylodon darwinii. Proceedings of the National Academy of Sciences of the United States of America, 93(1), 181-185. |
68 | Stone, A. C., Milner, G. R., Pääbo, S., & Stoneking, M. (1996). Sex determination of ancient human skeletons using DNA. American Journal of Physical Anthropology, 99(2), 231-238. |
69 | Höss, M., Jaruga, P., Zastawny, T. H., Dizdaroglu, M., & Pääbo, S. (1996). DNA damage and DNA sequence retrieval from ancient tissues. Nucleic Acids Research, 24(7), 1304-1307. |
70 | Tishkoff, S. A., Dietzsch, E., Speed, W., Pakstis, A. J., Kidd, J. R., Cheung, K., Bonné-Tamir, B., Santachiara-Benerecetti, A. S., Moral, P., Krings, M., Pääbo, S., Watson, E., Risch, N., Jenkins, T., & Kidd, K. K. (1996). Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science, 271(5254), 1380-1387. |
71 | Thomas, R., Zischler, H., Pääbo, S., & Stoneking, M. (1996). Novel mitochondrial DNA insertion polymorphism and its usefulness for human population studies. Human Biology, 68(6), 847-854. |
72 | Armour, J. A., Anttinen, T., May, C. A., Vega, E. E., Sajantila, A., Kidd, J. R., Kidd, K. K., Bertranpetit, J., Pääbo, S., & Jeffreys, A. J. (1996). Minisatellite diversity supports a recent African origin for modern humans. Nature Genetics, 13, 154-160. |
73 | Handt, O., Krings, M., Ward, R. H., & Pääbo, S. (1996). The retrieval of ancient human DNA sequences. American Journal of Human Genetics, 59(2), 368-376. |
74 | Börner, G. V., & Pääbo, S. (1996). Evolutionary fixation of RNA editing. Nature, 383, 225. |
75 | Poinar, H. N., Höss, M., Bada, J. L., & Pääbo, S. (1996). Amino acid racemization and the preservation of ancient DNA. Science, 272(5263), 864-866. |
76 | von Haeseler, A., Sajantila, A., & Pääbo, S. (1996). The genetical archaeology of the human genome. Nature Genetics, 14, 135-140. |
77 | Watson, E., Bauer, K., Aman, R., Weiss, G., von Haeseler, A., & Pääbo, S. (1996). mtDNA sequence diversity in Africa. American Journal of Human Genetics, 59(2), 437-444. |
78 | Sajantila, A., Salem, A., Savolainen, P., Bauer, K., Gierig, C., & Pääbo, S. (1996). Paternal and maternal DNA lineages reveal a bottleneck in the founding of the Finnish population. Proceedings of the National Academy of Sciences of the United States of America, 93(21), 12035-12039. |
79 | Salem, A. H., Badr, F. M., Gaballah, M. F., & Pääbo, S. (1996). The genetics of traditional living: Y-chromosomal and mitochondrial lineages in the Sinai Peninsula. American Journal of Human Genetics, 59(3), 741-743. |
80 | Börner, G., Mörl, M., Janke, A., & Pääbo, S. (1996). RNA editing changes the identity of a mitochondrial tRNA in marsupials. The EMBO Journal, 15(21), 5949-5957. |
81 | Pääbo, S. (1996). Mutational hot spots in the mitochondrial microcosm. American Journal of Human Genetics, 59(3), 493-496. |
82 | Petri, B., von Haeseler, A., & Pääbo, S. (1996). Extreme sequence heteroplasmy in bat mitochondrial DNA. Biological Chemistry, 377, 661-667. |
83 | Kilger, C., Krings, M., Poinar, H., & Pääbo, S. (1997). "Colony sequencing": Direct sequencing of plasmid DNA from bacterial colonies. Biotechniques, 22(3), 412-418. |
84 | Benes, V., Kilger, C., Voss, H., Pääbo, S., & Ansorge, W. (1997). Direct primer walking on P1 plasmid DNA. BioTechniques, 23(1), 98-100. |
85 | Yokobori, S.-i., & Pääbo, S. (1997). Polyadenylation creates the discriminator nucleotide of chicken mitochondrial tRNA Tyr. Journal of Molecular biology, 265(2), 95-99. |
86 | Petri, B., Pääbo, S., Haeseler, A. v., & Tautz, D. (1997). Paternity assessment and population subdivision in a natural population of the larger mouse-eared bat Myotis myotis. Molecular Ecology, 6(3), 235-242. |
87 | Kilger, C., & Pääbo, S. (1997). Direct exponential amplification and sequencing (DEXAS) of genomic DNA. Biological Chemistry Hoppe-Seyler (Berlin), 378(2), 99-105. |
88 | Kilger, C., & Pääbo, S. (1997). Direct DNA sequence determination from total genomic DNA. Nucleic Acids Research, 25(10), 2032-2032. |
89 | Krings, M., Stone, A. C., Schmitz, R. W., Krainitzki, H., Stoneking, M., & Pääbo, S. (1997). Neandertal DNA sequences and the origin of modern humans. Cell, 90(1), 19-30. |
90 | Laan, M., & Pääbo, S. (1997). Demographic history and linkage disequilibrium in human populations. Nature Genetics, 17, 435-438. |
91 | Börner, G. V., Yokobori, S.-i., Mörl, M., & Pääbo, S. (1997). RNA editing in metazoan mitochondria: staying fit without sex. FEBS Letters, 409(3), 2032-2034. |
92 | Cooper, A., Poinar, H. N., Pääbo, S., Radovcic, J., Debénath, A., Caparros, M., Barroso-Ruiz, C., Bertranpetit, J., Nielsen-Marsh, C., Hedges, R. E. M., & Sykes, B. (1997). Neandertal genetics. Science, 277(5329), 1021-1025. |
93 | Gravlung, P., Meldgaard, M., Pääbo, S., & Arctander, P. (1998). Polyphyletic origin of the small-bodied, high-arctic subspecies of tundra reindeer (Rangifer tarandus). Molecular Phylogenetics and Evolution, 10(2), 151-159. |
94 | Castresana, J., Feldmaier-Fuchs, G., & Pääbo, S. (1998). Codon reassignment and amino acid composition in hemichordate mitochondria. Proceedings of the National Academy of Sciences of the United States of America, 95(7), 3703-3707. |
95 | Terwilliger, J. D., Zöllner, S., Laan, M., & Pääbo, S. (1998). Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift Mapping' in small populations with no demographic expansion. Human Heredity, 48(3), 138-154. |
96 | Allen, M., Engström, A.-S., Meyer, S., Handt, O., Saldeen, T., von Haeseler, A., Pääbo, S., & Gyllenstein, U. (1998). Mitochondrial DNA sequencing of shed hairs and saliva on robbery caps: Sensitivity and matching probabilities. Journal of Forensic Sciences, 43(3), 453-464. |
97 | Castresana, J., Feldmaier-Fuchs, G., Yokobori, S.-i., Satoh, N., & Pääbo, S. (1998). The mitochondrial genome of the hemichordate Balanoglossus carnosus and the evolution of deuterostome mitochondria. Genetics, 150(3), 1115-1123. |
98 | Laan, M., & Pääbo, S. (1998). Mapping genes by drift-generated linkage disequilibrium. American Journal of Human Genetics, 63(2), 654-656. |
99 | Poinar, H. N., Hofreiter, M., Spaulding, W. G., Martin, P. S., Stankiewicz, A. B., Bland, H., Evershed, R. P., Possnert, G., & Pääbo, S. (1998). Molecular coproscopy: Dung and diet of the extinct ground sloth Nothrotheriops shastensis. Science, 281(5375), 402-406. |
100 | Cao, Y., Janke, A., Waddell, P. J., Westermann, M., Takenaka, O., Murata, S., Okada, N., Pääbo, S., & Hasegawa, M. (1998). Conflict among individual mitochondrial proteins in resolving the phylogeny of eutherian orders. Journal of Molecular Evolution, 47(3), 307-322. |
101 | Greenwood, A. D., & Pääbo, S. (1999). Nuclear insertion sequences of mitochondrial DNA predominate in hair but not in blood of elephants. Molecular Ecology, 8(1), 133-137. |
102 | Krings, M., Salem, A.-e.-H., Bauer, K., Geisert, H., Malek, A. K., Chaix, L., Simon, C., Welsby, D., Di Rienzo, A., Utermann, G., Sajantila, A., Pääbo, S., & Stoneking, M. (1999). mtDNA analysis of Nile River Valley populations: A genetic corridor or a barrier to migration? American Journal of Human Genetics, 64(4), 1166-1176. |
103 | Kaessmann, H., Heißig, F., Haeseler, A. v., & Pääbo, S. (1999). DNA sequence variation in a non-coding region of low recombination on the human X chromosome. Nature Genetics, 22(1), 78-81. |
104 | Krings, M., Geisert, H., Schmitz, R. W., Krainitzki, H., & Pääbo, S. (1999). DNA sequence of the mitochondrial hypervariable region II from the Neandertal type specimen. Proceedings of the National Academy of Sciences of the United States of America, 96(10), 5581-5585. |
105 | Greenwood, A. D., Capelli, C., Possnert, G., & Pääbo, S. (1999). Nuclear DNA sequences from late Pleistocene megafauna. Molecular Biology and Evolution, 16(11), 1466-1473. |
106 | Pääbo, S. (1999). Agriculture: Neolithic genetic engineering (News and Views). Nature, 398, 194-195. |
107 | Vigilant, L., & Pääbo, S. (1999). A chimpanzee millenium (Guest Editorial). Biological Chemistry, 380(12), 1353-1354. |
108 | Kaessmann, H., Wiebe, V., & Pääbo, S. (1999). Extensive nuclear DNA sequence diversity among chimpanzees. Science, 286(5442), 1159-1162. |
109 | Pääbo, S. (1999). Human evolution. Trends in Genetics, 15(12), M13-M16. |
110 | Yokobori, S.-i., Ueda, T., Feldmaier-Fuchs, G., Pääbo, S., Kondow, A., Nishikawa, K., & Watanabe, K. (1999). Complete DNA sequence of the mitochondrial genome of the ascidian Halocynthia roretzi (Chordata, Urochordata). Genetics, 153(4), 1851-1862. |
111 | Erlandsson, R., Wilson, J. F., & Pääbo, S. (2000). Sex chromosomal transposable element accumulation and male-driven substitutional evolution in humans. Molecular Biology and Evolution, 17(5), 804-812. |
112 | Börner, G. V., Zeviani, M., Tiranti, V., Carrara, F., Hoffmann, S., Gerbitz, K. D., Lochmüller, H., Klopstock, T., Pongratz, D., Melberg, A., Holme, E., & Pääbo, S. (2000). Decreased aminoacylation of mutant tRNAs in MELAS but not in MERRF patients. Human Molecular Genetics, 9(4), 467-475. |
113 | Pääbo, S. (2000). Of bears, conservation genetics, and the value of time travel (Commentary). Proceedings of the National Academy of Sciences USA, 97(4), 1320-1321. |
114 | Di Benedetto, G., Nasidze, I., Stenico, M., Nigro, L., Krings, M., Lanzinger, M., Vigilant, L., Stoneking, M., Pääbo, S., & Barbujani, G. (2000). Mitochondrial DNA sequences in prehistoric human remains from the Alps. European Journal of Human Genetics, 8(9), 669-677. |
115 | Hofreiter, M., Poinar, H. N., Spaulding, W. G., Bauer, K., Martin, P. S., Possnert, G., & Pääbo, S. (2000). A molecular analysis of ground sloth diet through the last glaciation. Molecular Ecology, 9(12), 1975-1984. |
116 | Krings, M., Capelli, C., Tschentscher, F., Geisert, H., Meyer, S., Haeseler, A. v., Grossschmidt, K., Possnert, G., Paunovic, M., & Pääbo, S. (2000). A view of Neandertal genetic diversity. Nature Genetics, 26, 144-146. |
117 | Ingman, M., Kaessmann, H., Pääbo, S., & Gyllenstein, U. (2000). Mitochondrial genome variation and the origin of modern humans. Nature, 408, 708-713. |
118 | Motz, M., Pääbo, S., & Kilger, C. (2000). Improved cycle sequencing of GC-rich templates by a combination of nucleotide analogs. BioTechniques, 29(2), 268-270. |
119 | Greenwood, A. D., Castresana, J., Feldmaier-Fuchs, G., & Pääbo, S. (2001). A molecular phylogeny of two extinct sloths. Molecular Phylogenetics and Evolution, 18(1), 94-103. |
120 | Kaessmann, H., Wiebe, V., Weiss, G., & Pääbo, S. (2001). Great ape DNA sequences reveal a reduced diversity and an expansion in humans. Nature Genetics, 27, 155-156. |
121 | Pääbo, S. (2001). The human genome and our view of ourselves. Science, 291(5507), 1219-1220. |
122 | Poinar, H. N., Kuch, M., Sobolik, K. D., Barnes, I., Stankiewicz, A. B., Kuder, T., Spaulding, W. G., Bryant, V. M., Cooper, A., & Pääbo, S. (2001). A molecular analysis of dietary diversity for three archaic Native Americans. Proceedings of the National Academy of Sciences USA, 98(8), 4317-4322. |
123 | Poinar, H. N., Kuch, M., & Pääbo, S. (2001). Molecular analyses of oral polio vaccine samples. Science, 292(5517), 743-744. |
124 | Hofreiter, M., Serre, D., Poinar, H. N., Kuch, M., & Pääbo, S. (2001). Ancient DNA. Nature Reviews Genetics, 2, 353-359. |
125 | Dörner, M., Altmann, M., Pääbo, S., & Mörl, M. (2001). Evidence for import of a lysyl-tRNA into marsupial mitochondria. Molecular Biology of the Cell, 12(9), 2688-2698. |
126 | Hofreiter, M., Jänicke, V. R., Serre, D., Haeseler, A. v., & Pääbo, S. (2001). DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA. Nucleic Acids Research, 29(23), 4793-4799. |
127 | Kaessmann, H., & Pääbo, S. (2002). The genetical history of humans and the great apes. Journal of Internal Medicine, 251(1), 1-18. |
128 | Kaessmann, H., Zöllner, S., Gustafsson, A. C., Wiebe, V., Laan, M., Lundeberg, J., Uhlen, M., & Pääbo, S. (2002). Extensive linkage disequilibrium in small human populations in Eurasia. American Journal of Human Genetics, 70(3), 673-685. |
129 | Hofreiter, M., Capelli, C., Krings, M., Waits, L., Conard, N. J., Munzel, S., Rabeder, G., Nagel, D., Paunovic, M., Jambresic, G., Meyer, S., Weiss, G., & Pääbo, S. (2002). Ancient DNA analyses reveal high mitochondrial DNA sequence diversity and parallel morphological evolution of late pleistocene cave bears. Molecular Biology and Evolution, 19(8), 1244-1250. |
130 | Ebersberger, I., Metzler, D., Schwarz, C., & Pääbo, S. (2002). Genomewide comparison of DNA sequences between humans and chimpanzees. American Journal of Human Genetics, 70(6), 1490-1497. |
131 | Enard, W., Khaitovich, P., Klose, J., Zöllner, S., Heißig, F., Giavalisco, P., Nieselt-Struwe, K., Muchmore, E., Varki, A., Ravid, R., Doxiadis, G. M., Bontrop, R. E., & Pääbo, S. (2002). Intra- and interspecific variation in primate gene expression patterns. Science, 296(5566), 340-343. |
132 | Enard, W., Przeworski, M., Fisher, S. E., Lai, C. S. L., Wiebe, V., Kitano, T., Monaco, A. P., & Pääbo, S. (2002). Molecular evolution of FOXP2, a gene involved in speech and language. Nature, 418(6900), 869-872. |
133 | Chou, H. H., Hayakawa, T., Diaz, S., Krings, M., Indriati, E., Leakey, M., Pääbo, S., Satta, Y., Takahata, N., & Varki, A. (2002). Inactivation of CMP-N-acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution. Proceedings of the National Academy of Sciences of the United States of America, 99(18), 11736-11741. |
134 | Motz, M., Sagner, G., Pääbo, S., & Kilger, C. (2003). Sequential DEXAS: A method for obtaining DNA sequences from genomic DNA and blood in one reaction. Nucleic Acids Research, 31(20): e121, pp. 1-8. |
135 | Schmitz, R. W., Serre, D., Bonani, G., Feine, S., Hillgruber, F., Krainitzki, H., Pääbo, S., & Smith, F. H. (2002). The Neandertal type site revisited: Interdisciplinary investigations of skeletal remains from the Neander Valley, Germany. Proceedings of the National Academy of Sciences of the United States of America, 99(20), 13342-13347. |
136 | Hellmann, I., Zöllner, S., Enard, W., Ebersberger, I., Nickel, B., & Pääbo, S. (2003). Selection on human genes as revealed by comparisons to chimpanzee cDNA. Genome Research, 13, 831-837. |
137 | Enard, W., Ebersberger, I., Fischer, A., Heißig, F., Hellmann, I., Höffner, B., Khaitovich, P., Kitano, T., Köhler, K., Metzler, D., Nickel, B., Przeworski, M., Schwarz, C., Nowick, K., Wiebe, V., Winkler, M., Zöllner, S., & Pääbo, S.(2002). Functional genomics in the chimpanzee. |
138 | Gilad, Y., Man, O., Pääbo, S., & Lancet, D. (2003). Human specific loss of olfactory receptor genes. Proceedings of the National Academy of Sciences of the United States of America, 100(6), 3324-3327. |
139 | Pääbo, S. (2003). The mosaic that is our genome. Nature, 421(6921), 409-412. |
140 | Gilad, Y., Bustamante, C. D., Lancet, D., & Pääbo, S. (2003). Natural selection on the olfactory receptor gene family in humans and chimpanzees. The American Journal of Human Genetics, 73(3), 489-501. |
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142 | Otte, K., Kranz, H., Kober, I., Thompson, P., Hoefer, M., Haubold, B., Remmel, B., Voss, H., Kaiser, C., Albers, M., Cheruvallath, Z., Jackson, D., Casari, G., Koegl, M., Pääbo, S., Mous, J., Kremoser, C., & Deuschle, U. (2003). Identification of Farnesoid X Receptor ß as a Novel Mammalian Nuclear Receptor Sensing Lanosterol. Molecular and Cellular Biology, 23(3), 864-872. |
143 | Kitano, T., Schwarz, C., Nickel, B., & Pääbo, S. (2003). Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees. Molecular Biology and Evolution, 20(8), 1281-1289. |
144 | Poinar, H. N., Kuch, M., McDonald, H. G., Martin, P. S., & Pääbo, S. (2003). Nuclear gene sequences from a late Pleistocene sloth coprolite. Current Biology, 13(13), 1150-1152. |
145 | Jänicke-Després, V. R., Buckler, E. S., Smith, B. D., Gilbert, M. T. P., Cooper, A., Doebley, J., & Pääbo, S. (2003). Early allelic selection in maize as revealed by ancient DNA. Science, 302(5648), 1206-1208. |
146 | Thalmann, O., Hebler, J., Poinar, H. N., Pääbo, S., & Vigilant, L. (2004). Unreliable mtDNA data due to nuclear insertions: A cautionary tale from analysis of humans and other great apes. Molecular Ecology, 13(2), 321-335. |
147 | Serre, D., Langaney, A., Chell, M., Teschler-Nicola, M., Paunovic, M., Mennecier, P., Hofreiter, M., Possnert, G., & Pääbo, S. (2004). No evidence of Neandertal mtDNA contribution to early modern humans. PLoS Biology, 2(3): e57, pp. 313-317. |
148 | Hofreiter, M., Rabeder, G., Jänicke-Després, V. R., Withalm, G., Nagel, D., Paunovic, M., Jambresic, G., & Pääbo, S. (2004). Evidence for reproductive isolation between cave bear populations. Current Biology, 14(1), 40-43. |
149 | Khaitovich, P., Muetzel, B., She, X., Lachmann, M., Hellmann, I., Dietzsch, J., Steigele, S., Do, H.-H., Weiss, G., Enard, W., Heißig, F., Arendt, T., Nieselt-Struwe, K., Eichler, E. E., & Pääbo, S. (2004). Regional patterns of gene expression in human and chimpanzee brains. Genome Research, 14, 1462-1473. |
150 | Fischer, A., Wiebe, V., Pääbo, S., & Przeworski, M. (2004). Evidence for a complex demographic history of chimpanzees. Molecular Biology and Evolution, 21(5), 799-808. |
151 | Ptak, S. E., Roeder, A. D., Stephens, M., Gilad, Y., Pääbo, S., & Przeworski, M. (2004). Absence of the TAP2 human recombination hotspot in chimpanzees. PLoS Biology, 2(6), 0849-0855. |
152 | Enard, W., Fassbender, A., Model, F., Adorján, P., Pääbo, S., & Olek, A. (2004). Differences in DNA methylation patterns between humans and chimpanzees. Current Biology, 14(4), R148-R149. |
153 | Enard, W., & Pääbo, S. (2004). Comparative primate genomics. Annual Review of Genomics and Human Genetics, 5, 351-378. |
154 | Gilad, Y., Wiebe, V., Przeworski, M., Lancet, D., & Pääbo, S. (2004). Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates. PLoS Biology, 2(1): e5 [V. Wiebe and S. Pääbo retracted authorship]. |
155 | Serre, D., Hofreiter, M., & Pääbo, S. (2004). Mutations induced by ancient DNA extracts? Molecular Biology and Evolution, 21(8), 1463-1467. |
156 | Khaitovich, P., Weiss, G., Lachmann, M., Hellmann, I., Enard, W., Muetzel, B., Wirkner, U., Ansorge, W., & Pääbo, S. (2004). A neutral model of transcriptome evolution. PLoS Biology, 2(5): e132, pp. 0682-0689. |
157 | Serre, D., & Pääbo, S. (2004). Evidence for gradients of human genetic diversity within and among continents. Genome Research, 14, 1679-1685. |
158 | The international Chimpanzee Chromosome 22 Consortium, Watanabe, H., Fujiyama, A., Hattory, M., Taylor, T. D., Toyoda, A., Kuroki, Y., Noguchi, H., BenKahla, A., Lehrach, H., Sudbrak, R., Kube, M., Taenzer, S., Galgoczy, P., Platzer, M., Scharfe, M., Nordsiek, G., Blöcker, H., Hellmann, I., Khaitovich, P., Pääbo, S., Reinhardt, R., Zheng, H.-J., Zhang, X.-L., Zhu, G.-F., Wang, B.-F., Fu, G., Ren, S.-X., Zhao, G.-P., Chen, Z., Lee, Y.-S., Cheong, J.-E., Choi, S.-H., Wu, K.-M., Liu, T.-T., Hsiao, K.-J., Tsai, S.-F., Kim, C.-G., Oota, S., Kitano, T., Kohora, Y., Saitou, N., Park, H.-S., Wang, S.-Y., Yaspo, M.-L., & Sakaki, Y. (2004). DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature, 429, 382-388. |
159 | Hofreiter, M., Serre, D., Rohland, N., Rabeder, G., Nagel, D., Conard, N. J., Münzel, S., & Pääbo, S. (2004). Lack of phylogeography in European mammals before the last glaciation. PNAS, 101(35), 12963-12968. |
160 | Pääbo, S., Poinar, H. N., Serre, D., Jänicke-Després, V. R., Hebler, J., Rohland, N., Kuch, M., Krause, J., Vigilant, L., & Hofreiter, M. (2004). Genetic analyses from ancient DNA. Annual Review of Genetics, 38, 645-679. |
161 | Fischer, A., Gilad, Y., Man, O., & Pääbo, S. (2005). Evolution of bitter taste receptors in humans and apes. Molecular Biology and Evolution, 22(3), 432-436. |
162 | Yohn, C. T., Jiang, Z., McGrath, S. D., Hayden, K. E., Khaitovich, P., Johnson, M. E., Eichler, M. Y., McPerson, J. D., Zhao, S., Pääbo, S., & Eichler, E. E. (2005). Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans. PLoS Biology, 3(4): e110. |
163 | Khaitovich, P., Hellmann, I., Enard, W., Nowick, K., Leinweber, M., Franz, H., Weiss, G., Lachmann, M., & Pääbo, S. (2005). Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees. Science, 309(5742), 1850-1854. |
164 | Laan, M., Wiebe, V., Khusnutdinova, E., Remm, M., & Pääbo, S. (2005). X-chromosome as a marker for population history: Linkage disequilibrium and haplotype study in Eurasian populations. European Journal of Human Genetics, 13(4), 452-462. |
165 | Ptak, S. E., Hinds, D. A., Köhler, K., Nickel, B., Patil, N., Ballinger, D. G., Przeworski, M., Frazer, K. A., & Pääbo, S. (2005). Fine-scale recombination patterns differ between chimpanzees and humans. Nature Genetics, 37(4), 429-434. |
166 | Hellmann, I., Prüfer, K., Ji, H. K., Zody, M. C., Pääbo, S., & Ptak, S. E. (2005). Why do human diversity levels vary at a megabase scale? Genome Research, 15(9), 1222-1231. |
167 | Rohland, N., Pollack, J. L., Nagel, D., Beauval, C., Airvaux, J., Pääbo, S., & Hofreiter, M. (2005). The population history of extant and extinct hyenas. Molecular Biology and Evolution, 22(12), 2435-2443. |
168 | Heißig, F., Krause, J., Bryk, J., Khaitovich, P., Enard, W., & Pääbo, S. (2005). Functional analysis of human and chimpanzee promoters. Genome Biology, 6: R57. |
169 | Beauval, C., Maureille, B., Lacrampe-Cuyaubere, F., Serre, D., Peressinotto, D., Bordes, J. G., Cochard, D., Couchoud, I., Dubrasquet, D., Laroulandie, W., Lenoble, A., Mallye, J. B., Pasty, S., Primault, J., Rohland, N., Pääbo, S., & Trinkaus, E. (2005). A late Neandertal femur from Les Rochers-de-Villeneuve, France. Proceedings of the National Academy of Sciences of the United States of America, 102(20), 7085-7090. |
170 | Khaitovich, P., Pääbo, S., & Weiss, G. (2005). Toward a neutral evolutionary model of gene expression. Genetics, 170(2), 929-939. |
171 | Krause, J., Dear, P. H., Pollack, J. L., Slatkin, M., Spriggs, H., Barnes, I., Lister, A. M., Ebersberger, I., Pääbo, S., & Hofreiter, M. (2006). Multiplex amplification of the mammoth mitochondrial genome and the evolution of Elephantidae. Nature, 439(7077), 724-727. |
172 | Noonan, J. P., Hofreiter, M., Smith, D., Priest, J. R., Rohland, N., Rabeder, G., Krause, J., Detter, J. C., Pääbo, S., & Rubin, E. M. (2005). Genomic sequencing of Pleistocene cave bears. Science, 309(5734), 597-599. |
173 | Franz, H., Ullmann, C., Becker, A., Ryan, M., Bahn, S., Arendt, T., Simon, M., Pääbo, S., & Khaitovich, P. (2005). Systematic analysis of gene expression in human brains before and after death. Genome Biology, 6(13): R112, pp. R112.1-R112.9. |
174 | Fraser, H. B., Khaitovich, P., Plotkin, J. B., Pääbo, S., & Eisen, M. B. (2005). Aging and gene expression in the primate brain. PLoS Biology, 3(9): e274, pp. 1653-1661. |
175 | Römpler, H., Schulz, A., Pitra, C., Coop, G., Przeworski, M., Pääbo, S., & Schöneberg, T. (2005). The rise and fall of the chemoattractant receptor GPR33. Journal of Biological Chemistry, 280(35), 31068-31075. |
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177 | Cheng, Z., Ventura, M., She, X., Khaitovich, P., Graves, T. A., Osoegawa, K., Church, D., de Jong, P., Wilson, R. K., Pääbo, S., Rocchi, M., & Eichler, E. E. (2005). A genome-wide comparison of recent chimpanzee and human segmental duplications. Nature, 437(7055), 88-93. |
178 | Khaitovich, P., Tang, K., Franz, H., Kelso, J., Hellmann, I., Enard, W., Lachmann, M., & Pääbo, S. (2006). Positive selection on gene expression in the human brain. Current Biology, 16(10), R356-R358. |
179 | Somel, M., Khaitovich, P., Bahn, S., Pääbo, S., & Lachmann, M. (2006). Gene expression becomes heterogeneous with age. Current Biology, 16(10), R359-R360. |
180 | Fish, J. L., Kosodo, Y., Enard, W., Pääbo, S., & Huttner, W. B. (2006). Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells. Proceedings of the National Academy of Sciences of the United States of America, 103(27), 10438-10443. |
181 | Prüfer, K., Muetzel, B., Do, H.-H., Weiss, G., Khaitovich, P., Rahm, E., Pääbo, S., Lachmann, M., & Enard, W. (2007). FUNC: A package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics, 8: 41. |
182 | Hublin, J.-J., & Pääbo, S. (2006). Neandertals. Current Biology, 16(4), R113-R114. |
183 | Khaitovich, P., Enard, W., Lachmann, M., & Pääbo, S. (2006). Evolution of primate gene expression. Nature Reviews Genetics, 7, 693-702. |
184 | Fischer, A., Pollack, J. L., Thalmann, O., Nickel, B., & Pääbo, S. (2006). Demographic history and genetic differentiation in apes. Current Biology, 16(11), 1133-1138. |
185 | Stiller, M., Green, R. E., Ronan, M. T., Simons, J. F., Du, L., Egholm, M., Rothberg, J. M., Keats, S. G., Ovodov, N. D., Antipina, E. E., Baryshnikov, G. F., Kuzmin, Y. V., Vasilevski, A. A., Wuenschell, G. E., Termini, J., Hofreiter, M., Jänicke-Després, V. R., Pääbo, S., & He, W. (2006). Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA. Proceedings of the National Academy of Sciences of the United States of America, 103(37), 13578-13584. |
186 | Noonan, J. P., Coop, G., Kudaravalli, S., Smith, D., Krause, J., Alessi, J., Chen, J., Platt, D., Pääbo, S., Pritchard, J. K., & Rubin, E. M. (2006). Sequencing and analysis of Neanderthal genomic DNA. Science, 314, 1113-1118. |
187 | Green, R. E., Krause, J., Ptak, S. E., Briggs, A. W., Ronan, M. T., Simons, J. F., Du, L., Egholm, M., Rothberg, J. M., Paunovic, M., & Pääbo, S. (2006). Analysis of one million base pairs of Neanderthal DNA. Nature, 444, 330-336. |
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309 | Prüfer, K., Filippo, C. d., Grote, S., Mafessoni, F., Korlevic, P., Hajdinjak, M., Vernot, B., Skov, L., Hsieh, P., Peyrégne, S., Reher, D., Hopfe, C., Nagel, S., Maricic, T., Fu, Q., Theunert, C., Rogers, R., Skoglund, P., Chintalapati, M., Dannemann, M., Nelson, B. J., Key, F. M., Rudan, P., Kucan, Ž., Gušic, I., Golovanova, L. V., Doronichev, V. B., Patterson, N., Reich, D., Eichler, E. E., Slatkin, M., Schierup, M. H., Andrés, A. M., Kelso, J., Meyer, M., & Pääbo, S. (2017). A high-coverage Neandertal genome from Vindija Cave in Croatia. Science, 358(6363), 655-658. |
310 | Yang, M. A., Gao, X., Theunert, C., Tong, H., Ayinuer-Petri, A., Nickel, B., Slatkin, M., Meyer, M., Pääbo, S., Kelso, J., & Fu, Q. (2017). 40,000-year-old individual from Asia provides insight into early population structure in Eurasia. Current Biology, 27(20), 3202-3208. |
311 | Hajdinjak, M., Fu, Q., Hübner, A., Petr, M., Mafessoni, F., Grote, S., Skoglund, P., Narasimham, V., Rougier, H., Crevecoeur, I., Semal, P., Soressi, M., Talamo, S., Hublin, J.-J., Gušic, I., Kucan, Ž., Rudan, P., Golovanova, L. V., Doronichev, V. B., Posth, C., Krause, J., Korlevic, P., Nagel, S., Nickel, B., Slatkin, M., Patterson, N., Reich, D., Prüfer, K., Meyer, M., Pääbo, S., & Kelso, J. (2018). Reconstructing the genetic history of late Neanderthals. Nature, 555(7698), 652-656. |
312 | Vernot, B., & Pääbo, S. (2018). The predecessors within.. (Commentary). Cell, 173(1), 6-7. |
313 | Loosdrecht, M. v. d., Bouzouggar, A., Humphrey, L., Posth, C., Barton, N., Ayinuer-Petri, A., Nickel, B., Nagel, S., Talbi, E. H., Hajraoui, M. A. E., Amzazi, S., Hublin, J.-J., Pääbo, S., Schiffels, S., Meyer, M., Haak, W., Jeong, C., & Krause, J. (2018). Pleistocene North African genomes link Near Eastern and sub-Saharan African human populations. Science, 360(6388), 548-552. |
314 | Slon, V., Mafessoni, F., Vernot, B., de Filippo, C., Grote, S., Viola, T. B., Hajdinjak, M., Peyrégne, S., Nagel, S., Brown, S., Douka, K., Higham, T., Kozlikin, M. B., Shunkov, M. V., Derevianko, A. P., Kelso, J., Meyer, M., Prüfer, K., & Pääbo, S. (2018). The genome of the offspring of a Neanderthal mother and a Denisovan father. Nature, 561(7721), 113-116. |
315 | Lamnidis, T. C., Majander, K., Jeong, C., Salmela, E., Wessman, A., Moiseyev, V., Khartanovich, V., Balanovsky, O., Ongyerth, M., Weihmann, A., Sajantila, A., Kelso, J., Pääbo, S., Onkamo, P., Haak, W., Krause, J., & Schiffels, S. (2018). Ancient Fennoscandian genomes reveal origin and spread of Siberian ancestry in Europe. Nature Communications, 9: 5018. |
316 | Gunz, P., Tilot, A. K., Wittfeld, K., Teumer, A., Shapland, C. Y., van Erp, T. G. M., Dannemann, M., Vernot, B., Neubauer, S., Guadalupe, T., Fernández, G., Brunner, H. G., Enard, W., Fallon, J., Hosten, N., Völker, U., Profico, A., Di Vincenzo, F., Manzi, G., Kelso, J., St. Pourcain, B., Hublin, J.-J., Franke, B., Pääbo, S., Macciardi, F., Grabe, H. J., & Fisher, S. E. (2019). Neandertal introgression sheds light on modern human endocranial globularity. Current Biology, 29(1), 120-127.e5. |
317 | Van Laer, B., Kapp, U., Soler-Lopez, M., Moczulska, K., Pääbo, S., Leonard, G., & Mueller-Dieckmann, C. (2018). Molecular comparison of Neanderthal and Modern Human adenylosuccinate lyase. Scientific Reports, 8: 18008. |
318 | Petr, M., Pääbo, S., Kelso, J., & Vernot, B. (2019). Limits of long-term selection against Neandertal introgression. Proceedings of the National Academy of Sciences, 116(5), 1639-1644. |
319 | Devièse, T., Massilani, D., Yi, S., Comeskey, D., Nagel, S., Nickel, B., Ribechini, E., Lee, J., Tseveendorj, D., Gunchinsuren, B., Meyer, M., Pääbo, S., & Higham, T. (2019). Compound-specific radiocarbon dating and mitochondrial DNA analysis of the Pleistocene hominin from Salkhit Mongolia. Nature Communications, 10(10): 274. |
320 | Douka, K., Slon, V., Jacobs, Z., Ramsey, C. B., Shunkov, M. V., Derevianko, A. P., Mafessoni, F., Kozlikin, M. B., Li, B., Grün, R., Comeskey, D., Devièse, T., Brown, S., Viola, B., Kinsley, L., Buckley, M., Meyer, M., Roberts, R. G., Pääbo, S., Kelso, J., & Higham, T. (2019). Age estimates for hominin fossils and the onset of the Upper Palaeolithic at Denisova Cave. Nature, 565(7741), 640-644. |
321 | Douka, K., Brown, S., Higham, T., Pääbo, S., Derevianko, A., & Shunkov, M. (2019). FINDER project: Collagen fingerprinting (ZooMS) for the identification of new human fossils. Antiquity, 93(367): e1. |
322 | Peyrégne, S., Slon, V., Mafessoni, F., de Filippo, C., Hajdinjak, M., Nagel, S., Nickel, B., Essel, E., Le Cabec, A., Wehrberger, K., Conard, N. J., Kind, C. J., Posth, C., Krause, J., Abrams, G., Bonjean, D., Di Modica, K., Toussaint, M., Kelso, J., Meyer, M., Pääbo, S., & Prüfer, K. (2019). Nuclear DNA from two early Neandertals reveals 80,000 years of genetic continuity in Europe. Science Advances, 5(6): eaaw5873. |
323 | Bokelmann, L., Hajdinjak, M., Peyrégne, S., Brace, S., Essel, E., de Filippo, C., Glocke, I., Grote, S., Mafessoni, F., Nagel, S., Kelso, J., Prüfer, K., Vernot, B., Barnes, I., Pääbo, S., Meyer, M., & Stringer, C. (2019). A genetic analysis of the Gibraltar Neanderthals. Proceedings of the National Academy of Sciences, 116(31), 15610-15615. |
324 | Riesenberg, S., Chintalapati, M., Macak, D., Kanis, P., Maricic, T., & Pääbo, S. (2019). Simultaneous precise editing of multiple genes in human cells. Nucleic Acids Research, 47(19): e116. |
325 | Kanton, S., Boyle, M. J., He, Z., Santel, M., Weigert, A., Sanchís-Calleja, F., Guijarro, P., Sidow, L., Fleck, J. S., Han, D., Qian, Z., Heide, M., Huttner, W. B., Khaitovich, P., Pääbo, S., Treutlein, B., & Camp, J. G. (2019). Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature, 574(7778), 418-422. |
326 | Hublin, J.-J., Sirakov, N., Aldeias, V., Bailey, S., Bard, E., Delvigne, V., Endarova, E., Fagault, Y., Fewlass, H., Hajdinjak, M., Kromer, B., Krumov, I., Marreiros, J., Martisius, N. L., Paskulin, L., Sinet-Mathiot, V., Meyer, M., Pääbo, S., Popov, V., Rezek, Z., Sirakova, S., Skinner, M. M., Smith, G. M., Spasov, R., Talamo, S., Tuna, T., Wacker, L., Welker, F., Wilcke, A., Zahariev, N., McPherron, S. P., & Tsanova, T. (2020). Initial Upper Palaeolithic Homo sapiens from Bacho Kiro Cave, Bulgaria. Nature, 581(7808), 299-302. |
327 | Zeberg, H., Kelso, J., & Pääbo, S. (2020). The Neandertal progesterone receptor. Molecular Biology and Evolution, 37(9): msaa119, pp. 2655-2660. |
328 | Mafessoni, F., Grote, S., de Filippo, C., Slon, V., Kolobova, K. A., Viola, B., Markin, S. V., Chintalapati, M., Peyrégne, S., Skov, L., Skoglund, P., Krivoshapkin, A. I., Derevianko, A. P., Meyer, M., Kelso, J., Peter, B., Prüfer, K., & Pääbo, S. (2020). A high-coverage Neandertal genome from Chagyrskaya Cave. Proceedings of the National Academy of Sciences, 117(26), 15132-15136. |
329 | Dannemann, M., He, Z., Heide, C., Vernot, B., Sidow, L., Kanton, S., Weigert, A., Treutlein, B., Pääbo, S., Kelso, J., & Camp, J. G. (2020). Human stem cell resources are an inroad to Neandertal DNA functions. Stem Cell Reports, 15, 214-225. |
330 | Khrameeva, E., Kurochkin, I., Han, D., Guijarro, P., Kanton, S., Santel, M., Qian, Z., Rong, S., Mazin, P., Sabirov, M., Bulat, M., Efimova, O., Tkachev, A., Guo, S., Sherwood, C. C., Camp, J. G., Pääbo, S., Treutlein, B., & Khaitovich, P. (2020). Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains. Genome Research, 30(5), 776-789. |
331 | Zeberg, H., Dannemann, M., Sahlholm, K., Tsuo, K., Maricic, T., Wiebe, V., Hevers, W., Robinson, H. P., Kelso, J., & Pääbo, S. (2020). A Neandertal sodium channel increases pain sensitivity in present-day humans. Current Biology, 30(17), 3465-3469. |
332 | Zhang, D., Xia, H., Chen, F., Li, B., Slon, V., Cheng, T., Yang, R., Jacobs, Z., Dai, Q., Massilani, D., Shen, X., Wang, J., Feng, X., Cao, P., Yang, M. A., Yao, J., Yang, J., Madsen, D. B., Han, Y., Ping, W., Liu, F., Perreault, C., Chen, X., Meyer, M., Kelso, J., Pääbo, S., & Fu, Q. (2020). Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau. Science, 370(6516), 584-587. |
333 | Massilani, D., Skov, L., Hajdinjak, M., Gunchinsuren, B., Tseveendorj, D., Yi, S., Lee, J., Nagel, S., Nickel, B., Devièse, T., Higham, T., Meyer, M., Kelso, J., Peter, B., & Pääbo, S. (2020). Denisovan ancestry and population history of early East Asians. Science, 370(6516), 579-583. |
334 | Zeberg, H., & Pääbo, S. (2020). The major genetic risk factor for severe COVID-19 is inherited from Neanderthals. Nature, 587(7835), 610-612. |
335 | Maricic, T., Nickel, O., Ayinuer-Petri, A., Essel, E., Gansauge, M.-T., Kanis, P., Macak, D., Riesenberg, S., Bokelmann, L., Zeberg, H., Meyer, M., Borte, S., & Pääbo, S. (2020). A direct RT-qPCR approach to test large numbers of individuals for SARS-CoV-2. PLoS One, 15(12): e0244824. |
336 | Zeberg, H., & Pääbo, S. (2021). A genomic region associated with protection against severe COVID-19 is inherited from Neandertals. Proceedings of the National Academy of Sciences, 118(9): e2026309118. |
337 | Bokelmann, L., Nickel, O., Maricic, T., Pääbo, S., Meyer, M., Borte, S., & Riesenberg, S. (2021). Point-of-care bulk testing for SARS-CoV-2 by combining hybridization capture with improved colorimetric LAMP. Nature Communications, 12(1): 1467. |
338 | Hajdinjak, M., Mafessoni, F., Skov, L., Vernot, B., Hübner, A., Fu, Q., Essel, E., Nagel, S., Nickel, B., Richter, J., Moldovan, O. T., Constantin, S., Endarova, E., Zahariev, N., Spasov, R., Welker, F., Smith, G. M., Sinet-Mathiot, V., Paskulin, L., Fewlass, H., Talamo, S., Rezek, Z., Sirakova, S., Sirakov, N., McPherron, S. P., Tsanova, T., Hublin, J.-J., Peter, B., Meyer, M., Skoglund, P., Kelso, J., & Pääbo, S. (2021). Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. Nature, 592, 253-257. |
339 | Zavala, E. I., Jacobs, Z., Vernot, B., Shunkov, M. V., Kozlikin, M. B., Derevianko, A. P., Essel, E., de Filippo, C., Nagel, S., Richter, J., Romagné, F., Schmidt, A., Li, B., O’Gorman, K., Slon, V., Kelso, J., Pääbo, S., Roberts, R. G., & Meyer, M. (2021). Pleistocene sediment DNA reveals hominin and faunal turnovers at Denisova Cave. Nature, 595, 399-403. |
340 | Stepanova, V., Moczulska, K., Vacano, G. N., Kurochkin, I., Ju, X.-C., Riesenberg, S., Macak, D., Maricic, T., Dombrowski, L., Schörnig, M., Anastassiadis, K., Baker, O., Naumann, R., Khrameeva, E., Vanushkina, A., Stekolschikova, E., Egorova, A., Nkatchev, A., Mazzarino, R., Duval, N., Zubkov, D., Giavalisco, P., Wilkinson, T. G., Patterson, D., Khaitovich, P., & Pääbo, S. (2021). Reduced purine biosynthesis in humans after their divergence from Neandertals. eLife, 10: e58741. |
341 | Maricic, T., Helmbrecht, N., Riesenberg, S., Macak, D., Kanis, P., Lackner, M., Pugach-Matveeva, A. D., & Pääbo, S. (2021). Comment on “Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment”. Science, 374(6565), 269. |
342 | Brown, S., Massilani, D., Kozlikin, M. B., Shunkov, M. V., Derevianko, A. P., Stoessel, A., Jope-Street, B., Meyer, M., Kelso, J., Pääbo, S., Higham, T., & Douka, K. (2022). The earliest Denisovans and their cultural adaptation. Nature Ecology & Evolution, 6, 28-35. |
343 | Riesenberg, S., Helmbrecht, N., Kanis, P., Maricic, T., & Pääbo, S. (2022). Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage. Nature Communications, 13: 489. |
344 | Massilani, D., Morley, M. W., Mentzer, S. M., Aldeias, V., Vernot, B., Miller, C., Stahlschmidt, M., Kozlikin, M. B., Shunkov, M. V., Derevianko, A. P., Conard, N. J., Wurz, S., Henshilwood, C. S., Vasquez, J., Essel, E., Nagel, S., Richter, J., Nickel, B., Roberts, R. G., Pääbo, S., Slon, V., Goldberg, P., & Meyer, M. (2022). Microstratigraphic preservation of ancient faunal and hominin DNA in Pleistocene cave sediments. Proceedings of the National Academy of Sciences, 119(1): e2113666118. |
345 | Coppo, L., Mishra, P., Siefert, N., Holmgren, A., Pääbo, S., & Zeberg, H. (2022). A substitution in the glutathione reductase lowers electron leakage and inflammation in modern humans. Science Advances, 8(1): eabm1148. |
346 | Mora-Bermúdez, F., Kanis, P., Macak, D., Peters, J., Naumann, R., Xing, L., Sarov, M., Winkler, S., Oegema, C. E., Haffner, C., Wimberger, P., Riesenberg, S., Maricic, T., Huttner, W. B., & Pääbo, S. (2022). Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development. Science Advances, 8: eabn7702. |
347 | Haeggström, S., Ingelman-Sundberg, M., Pääbo, S., & Zeberg, H. (2022). The clinically relevant CYP2C8*3 and CYP2C9*2 haplotype is inherited from Neandertals. The Pharmacogenomics Journal, 22, 247-249. |
348 | Oskolkov, N., Santel, M., Parikh, H. M., Ekström, O., Camp, J. G., Miyamoto-Mikami, E., Ström, K., Mir, B. A., Kryvokhyzha, D., Lehtovirta, M., Kobayashi, H., Kakigi, R., Naito, H., Eriksson, K.-F., Nystedt, B., Fuku, N., Treutlein, B., Pääbo, S., & Hansson, O. (2022). High-throughput muscle fiber typing from RNA sequencing data. Skeletal Muscle, 12: 16. |
349 | Peyrégne, S., Kelso, J., Peter, B. M., & Pääbo, S. (2022). The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals. eLife, 11: e75464. |
350 | Pinson, A., Xing, L., Namba, T., Kalebic, N., Peters, J., Oegema, C. E., Traikov, S., Reppe, K., Riesenberg, S., Maricic, T., Derihaci, R., Wimberger, P., Pääbo, S., & Huttner, W. B. (2022). Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals. Science, 377(6611): eabl6422, pp. 1170. |
351 | Skov, L., Peyrégne, S., Popli, D. R., Iasi, L. N., Devièse, T., Slon, V., Zavala, E. I., Hajdinjak, M., Sümer, A., Grote, S., Bossoms Mesa, A., López Herráez, D., Nickel, B., Nagel, S., Richter, J., Essel, E., Gansauge, M.-T., Schmidt, A., Korlevic, P., Comeskey, D., Derevianko, A. P., Kharevich, A., Markin, S. V., Talamo, S., Douka, K., Krajcarz, M. T., Roberts, R. G., Higham, T., Viola, B., Krivoshapkin, A. I., Kolobova, K. A., Kelso, J., Meyer, M., Pääbo, S., & Peter, B. M. (2022). Genetic insights into the social organization of Neanderthals. Nature, 610, 519-525. |
352 | Murat, F., Mbengue, N., Winge, S. B., Trefzer, T., Leushkin, E., Sepp, M., Cardoso-Moreira, M., Schmidt, J., Schneider, C., Mößinger, K., Brüning, T., Lamanna, F., Belles, M. R., Conrad, C., Kondova, I., Bontrop, R., Behr, R., Khaitovich, P., Pääbo, S., Marques-Bonet, T., Grützner, F., Almstrup, K., Schierup, M. H., & Kaessmann, H. (2023). The molecular evolution of spermatogenesis across mammals. Nature, 613, 308-316. |
353 | Lackner, M., Helmbrecht, N., Pääbo, S., & Riesenberg, S. (2023). Detection of unintended on-target effects in CRISPR genome editing by DNA donors carrying diagnostic substitutions. Nucleic Acids Research, 51(5): gkac1254. |
354 | Bornschein, U., Zeberg, H., Enard, W., Hevers, W., & Pääbo, S. (2023). Functional dissection of two amino acid substitutions unique to the human FOXP2 protein. Scientific Reports, 13(1): 3747. |
355 | Essel, E., Zavala, E. I., Schulz-Kornas, E., Kozlikin, M. B., Fewlass, H., Vernot, B., Shunkov, M. V., Derevianko, A. P., Douka, K., Barnes, I., Soulier, M.-C., Schmidt, A., Szymanski, M., Tsanova, T., Sirakov, N., Endarova, E., McPherron, S. P., Hublin, J.-J., Kelso, J., Pääbo, S., Hajdinjak, M., Soressi, M., & Meyer, M. (2023). Ancient human DNA recovered from a Palaeolithic pendant. Nature, 618, 328-332. |
356 | Ågren, R., Patil, S., Zhou, X., Sahlholm, K., Pääbo, S., & Zeberg, H. (2023). Major genetic risk factors for Dupuytren's disease are inherited from Neandertals. Molecular Biology and Evolution, 40(6): msad130. |
357 | Riesenberg, S., Kanis, P., Macak, D., Wollny, D., Düsterhöft, D., Kowalewski, J., Helmbrecht, N., Maricic, T., & Pääbo, S. (2023). Efficient high-precision homology-directed repair-dependent genome editing by HDRobust. Nature Methods, 20, 1388-1399. |
358 | Zeberg, H., Jakobsson, M., & Pääbo, S. (2024). [Review] The genetic changes that shaped Neandertals, Denisovans, and modern humans. Cell, 187, 1047-1058. |
359 | Xing, L., Gkini, V., Nieminen, A. I., Zhou, H.-C., Aquilino, M., Naumann, R., Reppe, K., Tanaka, K., Carmeliet, P., Heikinheimo, O., Pääbo, S., Huttner, W. B., & Namba, T. (2024). Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development. Nature Communications, 15(1): 3468. |
360 | Helmbrecht, N., Lackner, M., Maricic, T., & Pääbo, S. (2024). The modern human aryl hydrocarbon receptor is more active when ancestralized by genome editing. Proceedings of the National Academy of Sciences, 121(22): e2402159121. |
Bücher
1 | Pääbo, S. (2014). Neanderthal man: In search of lost genomes (Translated into 14 languages). New York: Basic Books. |
Rezensionen
1 | Pääbo, S. (1988). The mummy of Ramses II reconsidered: Book review of "La Momie de Ramsès II: contribution scientifique à l'égyptologie" sous la dir. [de] Lionel Balout.. Orientalische Literaturzeitung, 83(4), 389-394. |
2 | Pääbo, S. (1991). Molecular systematics at the crossroads: Book review of "Molecular systematics" ed. by D.M. Hillis and C. Moritz. Trends in Genetics, 7(8), 272. |
3 | Pääbo, S. (1993). Molecular Anthropology? Book review of "Molecular applications in biological anthropology" ed. by Eric J. Devor. Trends in Genetics, 9(7), 255. |
4 | Pääbo, S. (1997). A revolution in evolution: Book review of "Patterns in evolution: The new molecular view" by Roger Lewin. Nature, 386(6624), 456. |
Buchkapitel
1 | Hellerström, C., Andersson, A., Björkén, C., Eriksson, U., Groth, C., Gunnarsson, R., Hardstedt, C., Lundgren, G., Peterson, B., Pääbo, S., Swenne, I., Agren, A., & Östman, J. (1980). Isolation, culture and transplantation of human pancreatic islets. In I. Cumming, J. Funder, & F. A. Mendelsohn ( |
2 | Kämpe, O., Larhammer, D., Wiman, K., Schenning, L., Claesson, L., Gustafsson, K., Pääbo, S., Hyldig-Nielsen, J., Rask, L., & Peterson, P. (1983). Molecular analyses of MHC antigens. In E. Möller, & G. Möller ( |
3 | Pääbo, S. (1986). DNA is preserved in ancient Egyptian mummies. In A. David ( |
4 | Pääbo, S. (1990). Amplifying ancient DNA. In M. A. Innis ( |
5 | Simon, C., Pääbo, S., Kocher, T., & Wilson, A. (1990). Evolution of mitochondrial ribosomal RNA in insects as shown by the polymerase chain reaction. In M. T. Clegg, & S. J. O'Brian ( |
6 | Goloubinoff, P., Pääbo, S., & Wilson, A. C. (1991). Molecular characterization of ancient maize: Potentials and pitfalls. In S. Johannessen, & C. Hastorf ( |
7 | Pääbo, S., & Di Renzo, A. (1993). A molecular approach to the study of Egyptian history. In W. V. Davies, & R. Walker ( |
8 | Höss, M., Handt, O., & Pääbo, S. (1994). Recreating the past by PCR. In K. B. Mullis, F. Ferré, & R. A. Gibbs ( |
9 | Höss, M., & Pääbo, S. (1993). Ancient DNA. In McGraw-Hill Yearbook of Science (pp. 114-116). McGraw-Hill. |
10 | Mörl, M., Dörner, M., & Pääbo, S. (1994). Direct purification of tRNAs using oligonucleotides coupled to magnetic beads. In M. Uhlen, E. Horners, & O. Olsvik ( |
11 | Pääbo, S. (2000). Gene, Sprache und die Besiedelung des europäischen Nordens Europas - Zum Ursprung von Populationen aus molekulargenetischer Sicht. In Max-Planck-Gesellschaft ( |
12 | Poinar, H. N., & Pääbo, S. ( |
13 | Pääbo, S. (2002). Die Wurzeln der Menschheit - die Evolution des humanen Genoms. In M. Lessl, & G. Stock ( |
14 | Rabeder, G., Hofreiter, M., Nagel, D., Pääbo, S., & Withalm, G. (2002). Die neue Taxonomy der Höhlenbären. In W. Rosendahl, M. Morgan, & M. Correa ( |
15 | Pääbo, S. (2004). Ancient DNA. In Krude, T. ( |
16 | Pääbo, S. (2005). Was ist Forschung? In H. Braun, & D. Grömling ( |
17 | Serre, D., Schmitz, R. W., & Pääbo, S. (2006). Genetic analyses of the Neanderthals from the Feldhofer Caves. In Schmitz, Ralf W. ( |
18 | Serre, D., Langaney, A., Chech, M., Teschler-Nicola, M., Paunovic, M., Mennecier, P., Hofreiter, M., Possnert, G., & Pääbo, S. (2006). No evidence of Neandertal mtDNA contribution to early modern humans. In M. Teschler-Nicola ( |
19 | Serre, D., & Pääbo, S. (2006). The fate of European Neanderthals. In Katerina Harvati & Terry Harrison ( |
20 | Dabney, J., Meyer, M., & Pääbo, S. (2014). Ancient DNA damage. In E. C. Friedberg, S. J. Elledge, A. R. Lehmann, T. Lindahl, & M. Muzi-Falconi ( |
21 | Viola, B., & Pääbo, S. (2013). What's new in Central Asia? In M. V. Shunkov, & V. Molodin ( |
22 | Pääbo, S. (2015). The contribution of ancient hominin genomes from Siberia to our understanding of human evolution. In Herald of the Russian Academy of Sciences 85 (5): Papers by Laureates of the 2014 Lomonosov Grand Gold Medal of the Russian Academy of Sciences (pp. 392-396). Moscow: IAPC «Nauka/Interperiodica». |
23 | Pääbo, S. (2015). Genomy drevnich gominin iz Sibiri = Genomes of ancient hominins from Siberia. In Vestnik Rossijskoj Akademii Nauk 85 (10): Doklady Laureatov Bol'shoj Zolotoj Medali imeni M. V. Lomonosova Rossijskoj Akademii Nauk 2014 goda (pp. 879-884). Moscow: Nauka. |
24 | Pääbo, S. (2015). Dorcas Cummings Lecture: The Genetic Legacy of Neanderthals. In T. Grodzicker, D. Stewart, & B. Stillman ( |
25 | Pääbo, S. (2019). Lessons from our inner Neanderthal: How extinct hominins live on in people today; the genomes of now-extinct archaic humans can help us understand more about what makes us modern-day humans truly unique. In S. Shuzhen, & B. Seet ( |
Patents and Patent Applications
Pääbo, S., and Kilger, C.: Method for the direct, exponential amplification and sequencing of DNA molecules and its application. European patent: EP 1 004 677; US application: 991347, 311723, 33104; Japanese application: 9-351817.
Pääbo, S., and Kilger, C.: Method for the uncoupled, direct, exponential amplification and sequencing of DNA molecules with the addition of a second thermostable DNA polymerase and its application. European patent: EP 0 854 196; US applications: 08/991184, 357166, 339103; Japanese application: 9-353367.